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Angiogenesis in Health, Disease and Malignancy, Ali Salajegheh


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Автор: Ali Salajegheh
Название:  Angiogenesis in Health, Disease and Malignancy
ISBN: 9783319281384
Издательство: Springer
Классификация:

ISBN-10: 3319281380
Обложка/Формат: Hardcover
Страницы: 441
Вес: 0.82 кг.
Дата издания: 23.03.2016
Язык: English
Иллюстрации: Biography
Размер: 234 x 156 x 25
Читательская аудитория: Professional & vocational
Основная тема: Gene Function
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:

This book is about Angiogenesis. A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the formation of vascular supply, essential for delivering growth requirements such as oxygen and nutrients.

The book describes more than 100 genes and their key regulatory functions in the context of normal healthy condition, disease and malignancy, cancer proliferation and progression. New insights into the role of angiogenesis and the therapeutic inhibition of its regulators are investigated, due to the great potential for exploitation in the development of a novel treatment for cancer.

New scientists, junior researchers and biomedical science students will find this book an invaluable introductory reference to their insight about angiogenesis and angiogenic role of more than 100 angiogenes and their role in healthy, disease and malignant conditions.




Angiogenesis

Автор: Figg
Название: Angiogenesis
ISBN: 0387715177 ISBN-13(EAN): 9780387715179
Издательство: Springer
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Цена: 33428.00 р.
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Описание: Dr Judah Folkman (1933-2008) was considered the `father of angiogenesis`. Because of Folkman`s discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. This book presents a summary of tumor angiogenesis.

Mechanisms of Angiogenesis

Название: Mechanisms of Angiogenesis
ISBN: 3764364599 ISBN-13(EAN): 9783764364595
Издательство: Springer
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Цена: 26122.00 р.
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Описание: The induction of blood vessel growth as part of an adaptive process can be either exaggerated, such as in tumors, or too slow, as in ischemic diseases of heart and brain. Therefore it is an interesting target for medical intervention. This volume presents a thorough reconsideration of our current knowledge of factors and principles involved in angiogenic processes. It proceeds from a "macroscopic " perspective through cellular and physical mechanisms to the molecular level . In the first part, angiogenesis in physiological as well as pathological processes is described with a focus on embryogenesis, the reproductive system and the growing heart. The second part deals with cellular and physical mechanisms leading to angiogenesis, and the  last part presents a deeper insight into molecular mechanisms of blood vessel growth, including knockout studies of essential angiogenic molecules, the identification of signaling steps in angiogenesis and the importance of cellular junctions.

Angiogenesis and Anti-Angiogenesis in Hematological Malignancies

Автор: Ribatti
Название: Angiogenesis and Anti-Angiogenesis in Hematological Malignancies
ISBN: 940178034X ISBN-13(EAN): 9789401780346
Издательство: Springer
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Цена: 18284.00 р.
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Описание: Exploring the critical role of angiogenesis in tumor progression and metastasis, this book features the latest and most promising anti-angiogenesis molecules now being deployed in the battle against hematological malignancies such as leukemia and lymphoma.

The Role of Microenvironment in the Control of Tumor Angiogenesis

Автор: Domenico Ribatti
Название: The Role of Microenvironment in the Control of Tumor Angiogenesis
ISBN: 3319278185 ISBN-13(EAN): 9783319278186
Издательство: Springer
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Цена: 18284.00 р.
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Описание:

Prelims

1. Tumor microenvironment

1.1. Metastatic cascade

1.2. Epithelial-mesenchymal transition

1.3. The extracellular matrix

2. Tumor blood vessels and tumor endothelial cells

2.1. Tumor basement membrane

2.2. Tumor pericytes

3. Tumor angiogenesis

3.1. Sprouting angiogenesis

3.2. Vascular co-option

3.3. Vasculogenic mimicry

3.4. Intussusceptive microvascular growth

4. Inflammatory cells in tumor microenvironment

4.1. Neutrophils

4.2. Eosinophils and dendritic cells

4.3. Lymphocytes and platelets

4.4. Mast cells

4.5. Macrophages

4.6. Tie-2 expressing monocytes (TEMs)

4.7. Fibroblasts

4.8. Osteoblasts and osteoclasts

4.9. Cancer stem cells (CSCs)

4.10.Circulating endothelial cells and endothelial precursor cells

4.11. Multipotents adult progenitor cells (MAPCs) and myeloid-derived suppressor cells (MDSCs)

5. Therapeutic strategies, the concept of "normalization" and the role of VEGF inhibition


Index


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