Malaria, Maria M. Mota; Ana Rodriguez

Автор: Maria M.Mota; Ana Rodriguez
Название: Malaria
ISBN: 3319832395 ISBN-13(EAN): 9783319832395
Издательство: Springer
Цена: 20962.00 р.
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Описание: Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use.

However, there are a number of advanced candidate vaccines with high chances of success in the short term. Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following:- Contributions by top research leaders in the field,- Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately, - Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.

Автор: Krishna R. Dronamraju; Paolo Arese
Название: Malaria
ISBN: 1441921028 ISBN-13(EAN): 9781441921024
Издательство: Springer
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Описание: This book was originally conceived at a conference at the University of Turin in Italy. The conference was organized to examine the so-called "Malaria Hypothesis", that is to say, the higher fitness of t- lassemia heterozygotes in a malarial environment, and to pay tribute to the proponent of that hypothesis, J.B.S. Haldane. Contributors to this book examine certain genetic and evolutionary aspects of malaria which is a major killer of human populations, especially in Africa and Asia. There were attempts to discredit Haldane's contribution from two directions: (a) it has been suggested that the "Malaria Hypothesis" was known long before Haldane and that there was nothing original about his idea (Lederberg 1999), and that (b) the hypothesis of heterozygote su- riority was first suggested by the Italian biologist Giuseppe Montalenti who communicated his idea to Haldane (Allison 2004). Surely, both c- not be right. In fact, the evidence presented in this book clearly indicates that both are wrong. Haldane's malaria hypothesis has stimulated a great deal of research on the genetic, evolutionary and epidemiological aspects of malaria d- ing the last 50 years. It has opened up a whole new chapter in the study of infectious diseases. It deserves serious consideration. For helpful discussions we thank Lucio Luzzatto, Alberto Piazza, Guido Modiano and David Roberts.

Автор: Henry M. Staines; Sanjeev Krishna
Название: Treatment and Prevention of Malaria
ISBN: 3034808089 ISBN-13(EAN): 9783034808088
Издательство: Springer
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Описание: Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs.

Автор: Jean Langhorne
Название: Immunology and Immunopathogenesis of Malaria
ISBN: 3642421849 ISBN-13(EAN): 9783642421846
Издательство: Springer
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Описание: The death toll from malaria is still growing, with malaria-specific mortality in young African children estimated to have doubled during the last twenty years.