Isolation and Molecular Characterization of Circulating Tumor Cells, Mark Jesus M. Magbanua; John W. Park
Автор: Michail Ignatiadis; Christos Sotiriou; Klaus Pante Название: Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer ISBN: 364244587X ISBN-13(EAN): 9783642445873 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer.
Автор: Mark Jesus M. Magbanua; John W. Park Название: Circulating Tumor Cells ISBN: 1493971433 ISBN-13(EAN): 9781493971435 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume explores various approaches for enrichment, detection, isolation, and molecular profiling of circulating tumor cells (CTCs).
Автор: Peter B. Gahan Название: Circulating Nucleic Acids in Plasma and Serum ISBN: 9400790414 ISBN-13(EAN): 9789400790414 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis.
Автор: Martin C. Woodle; Gerrit Storm Название: Long Circulating Liposomes: Old Drugs, New Therapeutics ISBN: 3662221179 ISBN-13(EAN): 9783662221174 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. It provides the practicing clinician - in particular, oncologists and critical care infectious disease physicians - with the tools needed to use these new formulations towards the best outcome for the patient.
Автор: Max J. Coppes; Christine E. Campbell; Bryan Willia Название: Wilms Tumor: Clinical and Molecular Characterization ISBN: 3662226235 ISBN-13(EAN): 9783662226230 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: WT1 is a DNA Binding Protein Containing Four C2H2 Zinc Fingers . 113 WTI Mutations in Wilms Tumor . 114 Analysis of WTI Mutations in Tumors Other than Wilms Tumor . 137 Nephrogenic Rests, WTI Mutations and Wilms Tumor . 141 Wilms Tumor and Beckwith-Wiedemann Syndrome . 144 Wilms Tumor and Li-F raumeni Syndrome .
DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are interested in entering the field of circulating nucleic acids.
The areas covered in this volume include:
- Background and general biology of circulating nucleic acids
- Methodology
- Applications of circulating nucleic acids
- Quality Assurance
- Ethics
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