Cancer Systems Biology, Louise von Stechow

Автор: Pelengaris
Название: The Molecular Biology of Cancer, 2nd Edition
ISBN: 1118008812 ISBN-13(EAN): 9781118008812
Издательство: Wiley
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Описание: The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment.

Автор: Asfar S Azmi
Название: Systems Biology in Cancer Research and Drug Discovery
ISBN: 9400794355 ISBN-13(EAN): 9789400794351
Издательство: Springer
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Цена: 23508.00 р.
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Описание: A collation of chapters from the world`s leading experts in systems biology, this new publication traces its applications to cancer research and focuses on the use of the latest integrated and systems technologies in drug development and personalized medicine.

Автор: Alfredo Cesario; Frederick Marcus
Название: Cancer Systems Biology, Bioinformatics and Medicine
ISBN: 9401783659 ISBN-13(EAN): 9789401783651
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.

Автор: Rejniak
Название: Systems Biology of Tumor Microenvironment
ISBN: 3319420216 ISBN-13(EAN): 9783319420219
Издательство: Springer
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Цена: 22203.00 р.
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Описание: This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extracellular matrix, the interstitial fluid, and the immune and stromal cells. Mathematical models discussed here embrace both continuous and agent-based approaches, as well as mathematical frameworks of solid mechanics, fluid dynamics and optimal control theory. The topics in each chapter will be of interest to a biological community wishing to apply the mathematical methods to interpret their experimental data, and to a biomathematical audience interested in exploring how mathematical models can be used to address complex questions in cancer biology.

Автор: David H. Nguyen
Название: Systems Biology of Tumor Physiology
ISBN: 3319255991 ISBN-13(EAN): 9783319255996
Издательство: Springer
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Цена: 8489.00 р.
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Описание: This exciting SpringerBrief presents evidence for new ideas that will challenge several theories of how cancer biology is understood. However, this text combines the complex levels studying cancer at the molecular biology level, endocrinology level, and transcriptomics level.

Автор: Heiko Enderling; Nava Almog; Lynn Hlatky
Название: Systems Biology of Tumor Dormancy
ISBN: 1489998829 ISBN-13(EAN): 9781489998828
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This volume is based on the Workshop on Systems Biology of Tumor Dormancy meeting, held July 25th to July 28th, 2011.

Автор: Brown, Dennis M.
Название: Drug Delivery Systems In Cancer Therapy
ISBN: 0896038882 ISBN-13(EAN): 9780896038882
Издательство: Springer
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Цена: 30039.00 р.
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Описание: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Автор: P. Bringmann; E. Butcher; G. Parry; B. Weiss
Название: Systems Biology
ISBN: 364242158X ISBN-13(EAN): 9783642421587
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This volume features contributions from participants of an ESRF Workshop on "Systems Biology" held in Berkeley, USA, in November 2005. Recent successes and challenges of applying systems level measurements to the different steps of drug discovery and development in the pharmaceutical industry are summarized.