Structural Genomics and Drug Discovery, Wayne F. Anderson

Автор: Cornel Mulhardt
Название: Molecular Biology and Genomics,
ISBN: 0120885468 ISBN-13(EAN): 9780120885466
Издательство: Elsevier Science
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Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.

Автор: Yu Wai Chen
Название: Structural Genomics
ISBN: 1627036903 ISBN-13(EAN): 9781627036900
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This Methods in Molecular Biology book reviews the cloning and production of proteins for structural studies, experimental methods and computational methods and data analysis. Offers materials lists, reproducible protocols, troubleshooting tips and more.

Автор: Atta-ur-Rahman
Название: Drug Design and Discovery in Alzheimer`s Disease
ISBN: 0128039590 ISBN-13(EAN): 9780128039595
Издательство: Elsevier Science
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Цена: 15159.00 р.
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Описание:

Drug Design and Discovery in Alzheimer's Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of -amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery.

Автор: David Borsook; Lino R. Beccera; Edward Bullmore; R
Название: Imaging in CNS Drug Discovery and Development
ISBN: 1489984747 ISBN-13(EAN): 9781489984746
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Distilling the most salient developments in the use of imaging in drug development and disease mapping, this text integrates new imaging technologies and paradigms with molecular medicine and molecular profiling, and considers the relevant ethical issues.

Автор: Sridar V. Chittur
Название: Microarray Methods for Drug Discovery
ISBN: 1493957392 ISBN-13(EAN): 9781493957392
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Authoritative and cutting-edge, this book provides a single volume reference for all types of microarrays. It supplies new information on microarrays for cytogenetics and drug metabolism, and covers a wide range of microarray platforms.

Автор: Qing Yan
Название: Systems Biology in Drug Discovery and Development
ISBN: 1493957708 ISBN-13(EAN): 9781493957705
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Due to the failing “one-drug-fits-all” model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine.

Автор: Feng Wang
Название: Biomarker Methods in Drug Discovery and Development
ISBN: 1617379255 ISBN-13(EAN): 9781617379253
Издательство: Springer
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Цена: 25853.00 р.
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Описание: In this book, expert researchers provide a tool box for those who have a general interest in biomarker research and for those currently specializing in certain technologies but desiring an understanding of other available methodologies.

Автор: E. Morton Bradbury; S?ndor Pongor
Название: Structural Biology and Functional Genomics
ISBN: 0792357825 ISBN-13(EAN): 9780792357827
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Proceedings of the NATO Advanced Research Workshop, held in Trieste, Italy, 4-8 May 1999

Автор: Gy?rgy Marko-Varga
Название: Genomics and Proteomics for Clinical Discovery and Development
ISBN: 9401792011 ISBN-13(EAN): 9789401792011
Издательство: Springer
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Цена: 19564.00 р.
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Описание: The book is intended to be a resource for students as well as scientists in education and for the general public to learn about proteomics and genomics. Chromosomes form the basis for our genetic heritage and are the code for protein synthesis. The Human Genome Map came out in 2002, and the Proteome Sequence Map is under currently being created by a global consortia initiative. Proteome and genome building blocks already form the basis of scientific research areas as well as large parts of the pharmaceutical and biomedical industry. The book initiative will provide the background to and our current understanding of these gene and protein areas, as well as describe how cutting-edge science is using these resources to develop new medicines and new diagnostics for patient care and treatment. The book will be useful for undergraduate students as well as university students and researchers who need a good understanding of genomics and proteomics within the clinical field. The book will also be targeted at a broad public as well as readers not specialized within this field. Dr. Marko-Varga is the head of the Head of Div. Clinical Protein Science & Imaging at the Biomedical Center, Dept. of Measurement Technology and Industrial Electrical Engineering, Lund University, and Professor at the 1st Department of Surgery, Tokyo Medical University, Tokyo, Japan.

Автор: Qing Yan
Название: Pharmacogenomics in Drug Discovery and Development
ISBN: 1617378259 ISBN-13(EAN): 9781617378256
Издательство: Springer
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Цена: 23058.00 р.
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Описание: This comprehensive volume explores cutting-edge technologies used to pursue systems-based pharmacogenomics. Extensive chapters follow on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases.

Автор: Sridar V. Chittur
Название: Microarray Methods for Drug Discovery
ISBN: 1607616629 ISBN-13(EAN): 9781607616627
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Authoritative and cutting-edge, this book provides a single volume reference for all types of microarrays. It supplies new information on microarrays for cytogenetics and drug metabolism, and covers a wide range of microarray platforms.

Автор: Pierce Benjamin A
Название: Genetics Essentials. Concepts and Connections. - 3th ed.
ISBN: 1464190755 ISBN-13(EAN): 9781464190759
Издательство: Springer
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Цена: 9083.00 р.
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Описание: Derived from Ben Pierce's popular and acclaimed Genetics: A Conceptual Approach, this streamlined text covers basic transmission, molecular, and population genetics.