Автор: Greenwood Название: Antimicrobial Chemotherapy 5/e P. 2007 ISBN: 0198570163 ISBN-13(EAN): 9780198570165 Издательство: Oxford Academ Рейтинг: Цена: 6328.00 р. Наличие на складе: Поставка под заказ.
Описание: Aims to encourage good prescribing habits in doctors throughout the world, by describing the basic properties of antibiotics and other antimicrobial agents, and discussing the principles underlying the rational use of antimicrobial agents in the management of infection.
Автор: A,G. Mainous III; C, Pomeroy (Eds.) Название: Management of Antimicrobials in Infectious Diseases ISBN: 1603272380 ISBN-13(EAN): 9781603272384 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, a group of antimicrobial experts and experienced clinicians provide an eminently practical summary of the most effective evidence-based antimicrobial treatments encountered in both the hospital and outpatient settings.
Автор: Arch G. Mainous III; Claire Pomeroy Название: Management of Antimicrobials in Infectious Diseases ISBN: 1617796816 ISBN-13(EAN): 9781617796814 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, a group of antimicrobial experts and experienced clinicians provide an eminently practical summary of the most effective evidence-based antimicrobial treatments encountered in both the hospital and outpatient settings.
Автор: David A. Phoenix, Название: Novel Antimicrobial Agents and Strategies ISBN: 3527336389 ISBN-13(EAN): 9783527336388 Издательство: Wiley Рейтинг: Цена: 25336.00 р. Наличие на складе: Поставка под заказ.
Описание: A complete survey of current and future antimicrobial drugs and therapies, from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, and from metallic nanoparticles to photo- and sonosensitizers.
Автор: Flavia Marinelli; Olga Genilloud Название: Antimicrobials ISBN: 3662509083 ISBN-13(EAN): 9783662509081 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the “arms race” with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed.
Автор: Flavia Marinelli; Olga Genilloud Название: Antimicrobials ISBN: 3642399673 ISBN-13(EAN): 9783642399671 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This new volume shows that despite the increased media coverage of antibiotic resistance in hospitals and the community, our therapeutic options for battling bacteriological infection are being augmented by exciting new developments in the field.
Описание: Offers many antibiotics and antimicrobial compounds: in development, experimental, and in use. This title covers chemistry and synthesis, classification, structure-activity relationships, mechanisms of action and resistance, breakpoints, in vitro/in vivo activities, epidemiology, pharmacokinetics, metabolism, and adverse events.
Описание: The rapid advances made in the study of the synthesis, structure and function of biological macromole cules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division.
Автор: Paul Robert Hansen Название: Antimicrobial Peptides ISBN: 1493967355 ISBN-13(EAN): 9781493967353 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides basic and advanced laboratory protocols for the non-specialist and the experienced researcher. Chapters are divided into three parts covering synthesis and characterization of AMPs, studying the interaction of AMPs with model systems or bacteria, and assaying selected biological activities of AMPs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Antimicrobial Peptides: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Автор: Alexander A. Vinks; Hartmut Derendorf; Johan W. Mo Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics ISBN: 1493950819 ISBN-13(EAN): 9781493950812 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.
Автор: Anton Ficai, Alexandru Mihai Grumezescu Название: Nanostructures for antimicrobial therapy ISBN: 0323461522 ISBN-13(EAN): 9780323461528 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Поставка под заказ.
Описание:
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms.
Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments.
Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues.
Автор: Grumezescu, Alexander Mih Название: Antimicrobial Nanoarchitectonics ISBN: 0323527337 ISBN-13(EAN): 9780323527330 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Поставка под заказ.
Описание:
Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy.
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