Genetics Meets Metabolomics, Karsten Suhre

Название: Mass spectrometry in metabolomics
ISBN: 1493912577 ISBN-13(EAN): 9781493912575
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics.

Автор: Lammerhofer
Название: Metabolomics in Practice: Successful Strategies to Generate and Analyze Metabolic Data
ISBN: 3527330895 ISBN-13(EAN): 9783527330898
Издательство: Wiley
Рейтинг:
Цена: 14882.00 р.
Наличие на складе: Поставка под заказ.

Описание: Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation.

Автор: Jens Nielsen; Michael C. Jewett
Название: Metabolomics
ISBN: 3540747184 ISBN-13(EAN): 9783540747185
Издательство: Springer
Рейтинг:
Цена: 40389.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Giving a fresh, substantial and in-depth overview of the topic, this book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems.

Автор: M. Tomita; T. Nishioka
Название: Metabolomics
ISBN: 443199808X ISBN-13(EAN): 9784431998082
Издательство: Springer
Рейтинг:
Цена: 16977.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation.

Автор: Michael J. Hurley
Название: Genomic, Proteomic and Metabolomic Studies of Neurodegenerative
ISBN: 0128014806 ISBN-13(EAN): 9780128014806
Издательство: Elsevier Science
Рейтинг:
Цена: 24423.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Omic Studies of Neurodegenerative Disease: Part A is part of a well-established international series on neuroscience that examines major areas of basic and clinical research, along with emerging and promising subfields.

Автор: Wolfram Weckwerth
Название: Metabolomics
ISBN: 1617376434 ISBN-13(EAN): 9781617376436
Издательство: Springer
Рейтинг:
Цена: 25853.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.

Автор: Daniel Raftery
Название: Mass Spectrometry in Metabolomics
ISBN: 1493953192 ISBN-13(EAN): 9781493953196
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Part I. Historical and Methodology Overview

1. Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges

G. A. Nagana Gowda and Danijel Djukovic

Part II. Global LC-MS Based Metabolic Profiling

2. Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Yunpeng Qi, Yunlong Song, Haiwei Gu, Guorong Fan, and Yifeng Chai

3. LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations

Camilla B. Hill, Antony Bacic, and Ute Roessner

4. Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry

Young-Mi Go, Karan Uppal, Douglas I. Walker, ViLinh Tran, Lauriane Dury, Frederick H. Strobel, Hйlиne Baubichon-Cortay, Kurt D. Pennell, James R. Roede, and Dean P. Jones

5. Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling

Antoni Beltran, Sara Samino, and Oscar Yanes

Part III. Global GC-MS and CE-MS Based Metabolic Profiling

6. Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection

Luke C. Marney, Dr. Jamin C. Hoggard, Kristen J. Skogerboe, and Robert E. Synovec

7. Analysis of Mouse Liver Metabolites by GCЧGC-TOF MS

Xue Shi, Xinmin Yin, and Xiang Zhang

8. Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry

Antonia Garcia, Shama Naz, and Coral Barbas

Part IV. Isotope Labeling Methods

9. Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry

Ruokun Zhou and Liang Li

10. Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis

Hans Fredrik Nyvold Kvitvang, Kеre A. Kristiansen, Stina K. Lien, and Per Bruheim

11. Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS

Richard M. Higashi, Teresa W-M. Fan, Pawel K. Lorkiewicz, Hunter N.B. Moseley, and Andrew N. Lane

Part V. Targeted Aqueous Metabolite Profiling

12. Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRM

Ru Wei, Guodong Li, and Albert B. Seymour

Part VI. Lipid Profiling Methods

13. Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics

Miao Wang and Xianlin Han

14. Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass Spectrometry

Mojgan Masoodi and Dietrich A. Volmer

15. Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species

Juan Carlos Garcнa-Caсaveras, Marнa Teresa Donato, and Agustнn Lahoz

Part VII. Profiling Volatile Organic Compounds

16. Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis

Jan W. Dallinga, Agnieszka Smolinska, and Frederik-Jan van Schooten

17. Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs)

Shucha Zhang and Daniel Raftery

Part VIII. Profiling and Imaging using Atmospheric Sampling Methods

Автор: B.J. Nikolau; Eve Syrkin Wurtele
Название: Concepts in Plant Metabolomics
ISBN: 9048174082 ISBN-13(EAN): 9789048174089
Издательство: Springer
Рейтинг:
Цена: 32004.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Like genomics, which defines genes in a genome irrespective of functionality, metabolomics profiles all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules.

Автор: Datta
Название: Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry
ISBN: 3319458078 ISBN-13(EAN): 9783319458076
Издательство: Springer
Рейтинг:
Цена: 22359.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies.Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.

Автор: Dominique Rolin
Название: Metabolomics Coming of Age with its Technological Diversity,67
ISBN: 0123979226 ISBN-13(EAN): 9780123979223
Издательство: Elsevier Science
Рейтинг:
Цена: 24928.00 р.
Наличие на складе: Поставка под заказ.

Описание: Publishes reviews on a range of topics in plant sciences. This title features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. It features reviews on metabolomics coming of age with its technological diversity.