Metabolomics, M. Tomita; T. Nishioka

Автор: Lammerhofer
Название: Metabolomics in Practice: Successful Strategies to Generate and Analyze Metabolic Data
ISBN: 3527330895 ISBN-13(EAN): 9783527330898
Издательство: Wiley
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Описание: Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation.

Автор: David J. Beale; Konstantinos A. Kouremenos; Enzo A
Название: Microbial Metabolomics
ISBN: 3319463241 ISBN-13(EAN): 9783319463247
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This book brings together contributions from global experts who have helped to facilitate the exciting and rapid advances that are taking place in microbial metabolomics. The main application of this field is in clinical and veterinary microbiology, but there is a great potential to apply metabolomics to help to better understand complex biological systems that are dominated by multiple-species microbial populations exposed to changing growth and nutritional conditions. In particular, environmental (e.g., water, soil), food (e.g., microbial spoilage, food pathogens), and agricultural and industrial applications are seen as developing areas for microbial metabolomics. As such, the book includes contributions with clinical, environmental, and industrial perspectives.

Автор: Nigel W. Hardy; Robert D. Hall
Название: Plant Metabolomics
ISBN: 1493957481 ISBN-13(EAN): 9781493957484
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Estimating the metabolite complement of plant material involves a wide, and growing, range of techniques. This up-to-date guide provides stepwise, reproducible methodologies as well as key notes and implementation advice from experts in the field.

Название: Mass spectrometry in metabolomics
ISBN: 1493912577 ISBN-13(EAN): 9781493912575
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics.

Автор: B.J. Nikolau; Eve Syrkin Wurtele
Название: Concepts in Plant Metabolomics
ISBN: 9048174082 ISBN-13(EAN): 9789048174089
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Like genomics, which defines genes in a genome irrespective of functionality, metabolomics profiles all metabolites in a biological sample irrespective of the chemical and physical properties of these molecules.

Автор: John C. Lindon
Название: The Handbook of Metabonomics and Metabolomics,
ISBN: 0444528415 ISBN-13(EAN): 9780444528414
Издательство: Elsevier Science
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Цена: 32002.00 р.
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Описание: Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Автор: Ute Roessner; Daniel Anthony Dias
Название: Metabolomics Tools for Natural Product Discovery
ISBN: 1627035761 ISBN-13(EAN): 9781627035767
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This book presents methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses. It features step-by-step, readily reproducible protocols.

Автор: Xiaoquan Qi; Xiaoya Chen; Yulan Wang
Название: Plant Metabolomics
ISBN: 9401792909 ISBN-13(EAN): 9789401792905
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book introduces plant metabolomics, an experimental approach that is important in both functional genomics and systems biology. It can be argued that metabolite data is most closely linked to phenotypes and that changes in metabolite content or metabolic networks can therefore indicate gene function more directly than mRNA transcript or protein based-approaches. Additionally, the identification of metabolic markers has important applications in plant breeding. The book, written by researchers who are active in plant metabolomics in China, not only introduces the fundamental concepts and the latest methodological advances in the field of plant metabolomics, but also details new studies from the respective scientific programs of the authors and thus reflects the current state of domestic plant metabolomics research. Professor Xiaoquan Qi is the principal investigator at the Institute of Botany, CAS. Professor Xiaoya Chen is a member of the Chinese Academy of Science and also is the principal investigator at the Shanghai Institutes for Biological Sciences, CAS. Professor Yulan Wang is leading a team in BioSpectroscopy and Metabolomics at the Wuhan Institute of Physics and Mathematics, CAS.

Автор: Karsten Suhre
Название: Genetics Meets Metabolomics
ISBN: 1489996958 ISBN-13(EAN): 9781489996954
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Written by leading researchers, this book explores the intersection of genetics and metabolomics, and points the way to more comprehensive studies of inborn variation of metabolism. All chapters refer to one or more published experimental datasets.

Автор: Daniel Raftery
Название: Mass Spectrometry in Metabolomics
ISBN: 1493953192 ISBN-13(EAN): 9781493953196
Издательство: Springer
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Цена: 18167.00 р.
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Описание:

Part I. Historical and Methodology Overview

1. Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges

G. A. Nagana Gowda and Danijel Djukovic

Part II. Global LC-MS Based Metabolic Profiling

2. Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Yunpeng Qi, Yunlong Song, Haiwei Gu, Guorong Fan, and Yifeng Chai

3. LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations

Camilla B. Hill, Antony Bacic, and Ute Roessner

4. Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry

Young-Mi Go, Karan Uppal, Douglas I. Walker, ViLinh Tran, Lauriane Dury, Frederick H. Strobel, Hйlиne Baubichon-Cortay, Kurt D. Pennell, James R. Roede, and Dean P. Jones

5. Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling

Antoni Beltran, Sara Samino, and Oscar Yanes

Part III. Global GC-MS and CE-MS Based Metabolic Profiling

6. Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection

Luke C. Marney, Dr. Jamin C. Hoggard, Kristen J. Skogerboe, and Robert E. Synovec

7. Analysis of Mouse Liver Metabolites by GCЧGC-TOF MS

Xue Shi, Xinmin Yin, and Xiang Zhang

8. Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry

Antonia Garcia, Shama Naz, and Coral Barbas

Part IV. Isotope Labeling Methods

9. Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry

Ruokun Zhou and Liang Li

10. Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis

Hans Fredrik Nyvold Kvitvang, Kеre A. Kristiansen, Stina K. Lien, and Per Bruheim

11. Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS

Richard M. Higashi, Teresa W-M. Fan, Pawel K. Lorkiewicz, Hunter N.B. Moseley, and Andrew N. Lane

Part V. Targeted Aqueous Metabolite Profiling

12. Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRM

Ru Wei, Guodong Li, and Albert B. Seymour

Part VI. Lipid Profiling Methods

13. Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics

Miao Wang and Xianlin Han

14. Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass Spectrometry

Mojgan Masoodi and Dietrich A. Volmer

15. Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species

Juan Carlos Garcнa-Caсaveras, Marнa Teresa Donato, and Agustнn Lahoz

Part VII. Profiling Volatile Organic Compounds

16. Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis

Jan W. Dallinga, Agnieszka Smolinska, and Frederik-Jan van Schooten

17. Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs)

Shucha Zhang and Daniel Raftery

Part VIII. Profiling and Imaging using Atmospheric Sampling Methods

Автор: Alessandra Sussulini
Название: Metabolomics: From Fundamentals to Clinical Applications
ISBN: 3319476556 ISBN-13(EAN): 9783319476551
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine.

Автор: Dominique Rolin
Название: Metabolomics Coming of Age with its Technological Diversity,67
ISBN: 0123979226 ISBN-13(EAN): 9780123979223
Издательство: Elsevier Science
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Цена: 24928.00 р.
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Описание: Publishes reviews on a range of topics in plant sciences. This title features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. It features reviews on metabolomics coming of age with its technological diversity.