Inhibitory Control and Drug Abuse Prevention, Michael T. Bardo; Diana H. Fishbein; Richard Milic
Автор: Lorenzo A. Pinna; Patricia T.W. Cohen Название: Inhibitors of Protein Kinases and Protein Phosphates ISBN: 3642422063 ISBN-13(EAN): 9783642422065 Издательство: Springer Рейтинг: Цена: 69876.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles.
Автор: Vitaly A. Polunovsky; Peter J. Houghton Название: mTOR Pathway and mTOR Inhibitors in Cancer Therapy ISBN: 1617796948 ISBN-13(EAN): 9781617796944 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The target of rapamycin (TOR) was rst identi ed in Saccharomyces cerevisiae and subsequently in mammals (mTOR) as a conserved atypical serine/threonine kinase. Rapamycin was isolated as a product of the soil bacteria Streptomyces hygroscopicus, identi ed in a soil sample taken from the island of Rapa Nui (Easter Island).
Описание: Das Buch enthalt Kapitel uber: M. B. Bottorff, W. E. Evans, Memphis, TN, USA: Uberwachung der Medikament-KonzentrationE. Truscheit, I. Hillebrand, B. Junge, L. Muller, W. Puls, D. D. Schmidt, Wuppertal, FRG: Inhibitoren der mikrobiellen alpha-Glucosidase: Chemie, Biochemie und potentielle therapeutische AnwendungenH. Will, Berlin-Buch, GDR: Plasminogen-Aktivatoren: Molekuleigenschaften, biologische Zellfunktion und klinische Anwendung
Автор: H. Kersten; W. Kersten Название: Inhibitors of Nucleic Acid Synthesis ISBN: 3642808573 ISBN-13(EAN): 9783642808579 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although the biochemistry of nucleic acid synthesis is known in general, the precise molecular mechanisms by which deoxyribonucleic acid is replicated or transcribed has still to be clarified.
Автор: Goran Claeson; Michael F. Scully; Vijay V. Kakkar; Название: The Design of Synthetic Inhibitors of Thrombin ISBN: 030644593X ISBN-13(EAN): 9780306445934 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The symposium was organized in four sessions: (1) Structural features of the interaction of thrombin with substrates and inhibitors, (2) Synthetic inhibitors, (3) Hirudin and its analogues, and (4) Pharmacological and clinical considerations.
Автор: Sir John R. Vane; Jack H. Botting; R.M. Botting Название: Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors ISBN: 9401090319 ISBN-13(EAN): 9789401090315 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thus the anti-inflammatory actions of non-steroid anti-inflammatory drugs (NSAIDs) may be due to the inhibition of COX-2, whereas the unwanted side-effects such as irritation of the stomach lining and toxic effects on the kidney are due to inhibition of the constitutive enzyme, COX-I.
Автор: Goran Claeson; Michael F. Scully; Vijay V. Kakkar; Название: The Design of Synthetic Inhibitors of Thrombin ISBN: 1489924205 ISBN-13(EAN): 9781489924209 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The symposium was organized in four sessions: (1) Structural features of the interaction of thrombin with substrates and inhibitors, (2) Synthetic inhibitors, (3) Hirudin and its analogues, and (4) Pharmacological and clinical considerations.
Автор: Alexey Larionov Название: Resistance to Aromatase Inhibitors in Breast Cancer ISBN: 3319382845 ISBN-13(EAN): 9783319382845 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance.
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