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Inhibitory Control and Drug Abuse Prevention, Michael T. Bardo; Diana H. Fishbein; Richard Milic


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Автор: Michael T. Bardo; Diana H. Fishbein; Richard Milic
Название:  Inhibitory Control and Drug Abuse Prevention
ISBN: 9781493902248
Издательство: Springer
Классификация:




ISBN-10: 1493902245
Обложка/Формат: Paperback
Страницы: 335
Вес: 0.49 кг.
Дата издания: 20.08.2014
Язык: English
Издание: 2011 ed.
Иллюстрации: Xiv, 335 p.
Размер: 234 x 156 x 19
Читательская аудитория: General (us: trade)
Основная тема: Medicine & Public Health
Подзаголовок: From Research to Translation
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The purpose of this book is to review our state of knowledge about the neurobehavioral and psychosocial processes involved in behavioral inhibitory processes and to provide an insight into how these basic research findings may be translated into the practice of drug abuse prevention interventions. Over the last decade, there has been a wealth of information indicating that substance use disorders do not simply reflect an exaggeration of reward seeking behavior, but that they also represent a dysfunction of behavioral inhibitory processes that are critical in exercising self-control. A number of studies have determined that individuals with substance use disorders have poor inhibitory control compared to non-abusing individuals. In addition, the fact that the adolescent period is often characterized by a lack of inhibitory control may be one important reason for the heightened vulnerability for the initiation of drug use during this time. Controlled experiments utilizing neuroscience techniques in laboratory animals or neuroimaging techniques in humans have revealed that individual differences in prefrontal cortical regions may underlie, at least in part, these differences in inhibitory control. Although a few excellent journal reviews have been published on the role of inhibitory deficits in drug abuse, there has been relatively little attention paid to the potential applications of this work for drug abuse prevention. The current book will provide both basic and applied researchers with an overview of this important health-relevant topic. Since translational research cuts across multiple disciplines and most readers are not familiar with all of these disciplines, the reading level will be geared to be accessible to graduate students, as well as to faculty and researchers in the field. The book will be organized around three general themes, encased within introductory and concluding chapters. The first theme will review basic neurobehavioral research findings on inhibition and drug abuse. Chapters in this theme will emphasize laboratory studies using human volunteers or laboratory animals that document the latest research implicating a relation between inhibition and drug abuse at both the neural and behavioral levels of analysis. The second theme will move the topic to at-risk populations that have impulse control problems, including children, adolescents and young adults. The third theme will concentrate on prevention science as it relates to inhibitory control. Chapters in this theme will be written by experts attempting to develop and improve prevention interventions by integrating evidence-based knowledge about inhibitory control processes. In all of the chapters, writers will be asked to speculate about innovative approaches that may be useful for the practice of prevention.
Дополнительное описание: I. Introduction.- Benefits of a translating research on inhibitory control for the prevention drug abuse.- II. Neurobehavioral Approaches for Understanding Inhibitory Control.- Animal models of inhibitory control.- Neurochemical influences on impulsivity



Inhibitors of Protein Kinases and Protein Phosphates

Автор: Lorenzo A. Pinna; Patricia T.W. Cohen
Название: Inhibitors of Protein Kinases and Protein Phosphates
ISBN: 3642422063 ISBN-13(EAN): 9783642422065
Издательство: Springer
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Цена: 69876.00 р.
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Описание: The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles.

mTOR Pathway and mTOR Inhibitors in Cancer Therapy

Автор: Vitaly A. Polunovsky; Peter J. Houghton
Название: mTOR Pathway and mTOR Inhibitors in Cancer Therapy
ISBN: 1617796948 ISBN-13(EAN): 9781617796944
Издательство: Springer
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Цена: 28732.00 р.
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Описание: The target of rapamycin (TOR) was rst identi ed in Saccharomyces cerevisiae and subsequently in mammals (mTOR) as a conserved atypical serine/threonine kinase. Rapamycin was isolated as a product of the soil bacteria Streptomyces hygroscopicus, identi ed in a soil sample taken from the island of Rapa Nui (Easter Island).

Drug Concentration Monitoring Microbial Alpha-Glucosidase Inhibitors Plasminogen Activators

Автор: Michael B Bottorff; William E. Evans; Ingrid Hille
Название: Drug Concentration Monitoring Microbial Alpha-Glucosidase Inhibitors Plasminogen Activators
ISBN: 3642734634 ISBN-13(EAN): 9783642734632
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Das Buch enthalt Kapitel uber: M. B. Bottorff, W. E. Evans, Memphis, TN, USA: Uberwachung der Medikament-KonzentrationE. Truscheit, I. Hillebrand, B. Junge, L. Muller, W. Puls, D. D. Schmidt, Wuppertal, FRG: Inhibitoren der mikrobiellen alpha-Glucosidase: Chemie, Biochemie und potentielle therapeutische AnwendungenH. Will, Berlin-Buch, GDR: Plasminogen-Aktivatoren: Molekuleigenschaften, biologische Zellfunktion und klinische Anwendung

Inhibitors of Nucleic Acid Synthesis

Автор: H. Kersten; W. Kersten
Название: Inhibitors of Nucleic Acid Synthesis
ISBN: 3642808573 ISBN-13(EAN): 9783642808579
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Although the biochemistry of nucleic acid synthesis is known in general, the precise molecular mechanisms by which deoxyribonucleic acid is replicated or transcribed has still to be clarified.

The Design of Synthetic Inhibitors of Thrombin

Автор: Goran Claeson; Michael F. Scully; Vijay V. Kakkar;
Название: The Design of Synthetic Inhibitors of Thrombin
ISBN: 030644593X ISBN-13(EAN): 9780306445934
Издательство: Springer
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Цена: 32004.00 р.
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Описание: The symposium was organized in four sessions: (1) Structural features of the interaction of thrombin with substrates and inhibitors, (2) Synthetic inhibitors, (3) Hirudin and its analogues, and (4) Pharmacological and clinical considerations.

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors

Автор: Sir John R. Vane; Jack H. Botting; R.M. Botting
Название: Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors
ISBN: 9401090319 ISBN-13(EAN): 9789401090315
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Thus the anti-inflammatory actions of non-steroid anti-inflammatory drugs (NSAIDs) may be due to the inhibition of COX-2, whereas the unwanted side-effects such as irritation of the stomach lining and toxic effects on the kidney are due to inhibition of the constitutive enzyme, COX-I.

The Design of Synthetic Inhibitors of Thrombin

Автор: Goran Claeson; Michael F. Scully; Vijay V. Kakkar;
Название: The Design of Synthetic Inhibitors of Thrombin
ISBN: 1489924205 ISBN-13(EAN): 9781489924209
Издательство: Springer
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Цена: 20962.00 р.
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Описание: The symposium was organized in four sessions: (1) Structural features of the interaction of thrombin with substrates and inhibitors, (2) Synthetic inhibitors, (3) Hirudin and its analogues, and (4) Pharmacological and clinical considerations.

Resistance to Aromatase Inhibitors in Breast Cancer

Автор: Alexey Larionov
Название: Resistance to Aromatase Inhibitors in Breast Cancer
ISBN: 3319382845 ISBN-13(EAN): 9783319382845
Издательство: Springer
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Цена: 18284.00 р.
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Описание: Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance.


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