The Design of Synthetic Inhibitors of Thrombin, Goran Claeson; Michael F. Scully; Vijay V. Kakkar;

Автор: Michael E. Maragoudakis; Nikos E. Tsopanoglou
Название: Thrombin
ISBN: 1441918779 ISBN-13(EAN): 9781441918772
Издательство: Springer
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Цена: 24456.00 р.
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Описание: Thrombin and thrombin receptors are involved in many physiological processes and can contribute to a variety of disease states. This book will stimulate interest in new targets of drug development and increase our understanding of the multiplicity of thrombin.

Автор: Michel Pairet; Joanne van Ryn
Название: COX-2 Inhibitors
ISBN: 3034896077 ISBN-13(EAN): 9783034896078
Издательство: Springer
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Цена: 20962.00 р.
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Описание: COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.

Автор: Gerry A. Higgs; Brian Henderson
Название: Novel Cytokine Inhibitors
ISBN: 3034895720 ISBN-13(EAN): 9783034895729
Издательство: Springer
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Цена: 6986.00 р.
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Описание: It addresses different therapeutic intervention possibilities for new drugs, such as the cellular source of cytokines, specific receptors which induce cytokine synthesis, intracellular regulators of cytokine gene induction and expression, secretion and activation of cytokines, cytokine receptors and signalling pathways from these receptors.

Автор: Barry W. Festoff
Название: Serine Proteases and Their Serpin Inhibitors in the Nervous System
ISBN: 1468483595 ISBN-13(EAN): 9781468483598
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of a NATO ARW held in Maratea, Italy, July 2-8, 1989

Автор: Goran Claeson; Michael F. Scully; Vijay V. Kakkar;
Название: The Design of Synthetic Inhibitors of Thrombin
ISBN: 030644593X ISBN-13(EAN): 9780306445934
Издательство: Springer
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Цена: 32004.00 р.
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Описание: The symposium was organized in four sessions: (1) Structural features of the interaction of thrombin with substrates and inhibitors, (2) Synthetic inhibitors, (3) Hirudin and its analogues, and (4) Pharmacological and clinical considerations.

Автор: Lawrence J. Berliner
Название: Thrombin
ISBN: 1461364507 ISBN-13(EAN): 9781461364504
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Research on thrombin structure and function has progressed significantly over the past three decades. Part 2, Biochemistry, includes chapters on synthetic thrombin inhibitors, protein inhibitors (e.g., antithrombin III, hirudin), and thrombin interactions with factor XIII.

Автор: Sir John R. Vane; Jack H. Botting
Название: Selective COX-2 Inhibitors
ISBN: 940106041X ISBN-13(EAN): 9789401060417
Издательство: Springer
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Цена: 13974.00 р.
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Описание: ` The elucidation of the crystal structure of these different enzymes and the skills of medicinal chemists have led to the synthesis of new chemicals with a selectivity for the inducible enzyme, and thus with therapeutic efficacy without those toxic effects result- ing from inhibition of the constitutive enzyme.

Автор: A.R. Kennedy; W. Troll
Название: Protease Inhibitors as Cancer Chemopreventive Agents
ISBN: 1461362490 ISBN-13(EAN): 9781461362494
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Protease inhibitors (PIs) are widely distributed in plants and animals, and have a variety of functions, which include preventing digestion of seeds by insects and modifying blood clotting in animals.

Автор: Giancarlo Folco; Bengt Samuelsson; Robert C. Murph
Название: Novel Inhibitors of Leukotrienes
ISBN: 3034897367 ISBN-13(EAN): 9783034897365
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Many new antileukotriene drugs are now marketed as antiasthma drugs and represent the first new drugs in this field since the 1970s.

Автор: G. Strube
Название: ACE Inhibitors in Hypertension
ISBN: 9401057370 ISBN-13(EAN): 9789401057370
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The treatment of hypertension has progressed in stages following the development of a succession of increasingly effective drugs, each allowing a greater proportion of patients to be treated with fewer and fewer side-effects.