Автор: M. Endo; Y. Kurachi; M. Mishina Название: Pharmacology of Ionic Channel Function: Activators and Inhibitors ISBN: 3540661271 ISBN-13(EAN): 9783540661276 Издательство: Springer Рейтинг: Цена: 78366.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: G. Strube Название: ACE Inhibitors in Hypertension ISBN: 0792389638 ISBN-13(EAN): 9780792389637 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reviews the use of ACE inhibitors in treating hypertension in general (family) practice. This guide also serves as a reference for basic information on the pharmacology and mode of action of this relatively novel class of drugs. It reflects the needs of practitioners by emphasizing the pragmatic view. It includes Epidemiology and pharmacology.
Автор: Bernhard Kuster Название: Kinase Inhibitors ISBN: 1493957570 ISBN-13(EAN): 9781493957576 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this Methods in Molecular Biology (TM) volume, experts in kinase biology, drug discovery and clinical research present exemplary methods for addressing the challenges involved in discovery and development of kinase inhibitors both for research and clinical use.
Автор: J. Cheronis; Repine Название: Proteases, Protease Inhibitors and Protease-Derived Peptides ISBN: 3034873999 ISBN-13(EAN): 9783034873994 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Lorenzo A. Pinna; Patricia T.W. Cohen Название: Inhibitors of Protein Kinases and Protein Phosphates ISBN: 3642422063 ISBN-13(EAN): 9783642422065 Издательство: Springer Рейтинг: Цена: 69876.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles.
Автор: Alexey Larionov Название: Resistance to Aromatase Inhibitors in Breast Cancer ISBN: 3319382845 ISBN-13(EAN): 9783319382845 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance.
Автор: Nicola J. Curtin; Ricky A. Sharma Название: PARP Inhibitors for Cancer Therapy ISBN: 3319141503 ISBN-13(EAN): 9783319141503 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer.
Автор: Goran Claeson; Michael F. Scully; Vijay V. Kakkar; Название: The Design of Synthetic Inhibitors of Thrombin ISBN: 030644593X ISBN-13(EAN): 9780306445934 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The symposium was organized in four sessions: (1) Structural features of the interaction of thrombin with substrates and inhibitors, (2) Synthetic inhibitors, (3) Hirudin and its analogues, and (4) Pharmacological and clinical considerations.
Описание: One of the most important developments in the field of cardiovascular medicine over the last two decades has been recognition of the key role played by arterial thrombosis in the pathogenesis of acute coronary syndromes, ischemic complications of percutane- ous coronary revascularization, and coronary and peripheral atherosclerosis. The phar- macologic armamentarium directed against vascular thrombosis has thus expanded substantially during that time, with development of new fibrinolytic agents, low-molecu- lar-weight heparins, direct thrombin inhibitors, antagonists to platelet activation, and the platelet glycoprotein lIb/IlIa inhibitors. Though clinical investigations of these com- pounds have been marked by failures as well as successes, there is little doubt that enhanced antithrombotic therapies have markedly improved the outcome of patients undergoing coronary revascularization or with acute coronary syndromes. Glycoprotein IIblIlIa receptor antagonists were introduced into clinical practice to overcome the limitations of approaches that inhibit only individual pathways of platelet activation. Multiple mechanisms of platelet activation in response to different agonists converge on the platelet membrane glycoprotein IIblIlIa complex, the "final common pathway" of platelet aggregation. The clinical hemorrhagic syndrome caused by a rare inherited defect in this receptor (Glanzmann' s thrombasthenia), characterized by muco- cutaneous and postsurgical bleeding, but infrequent spontaneous organ (particularly central nervous system) bleeding, suggested that therapeutic inhibition of this receptor might be a potent, yet well-tolerated means of treating thrombotic disorders.
Автор: Louis M. Aledort; Leon W. Hoyer; Jeanne M. Lusher; Название: Inhibitors to Coagulation Factors ISBN: 1461380014 ISBN-13(EAN): 9781461380016 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Second International Symposium held in Chapel Hill, North Carolina, November 3-5, 1993
Автор: A. Hjalmarsson; W.J. Remme Название: Sinus node inhibitors ISBN: 3798508615 ISBN-13(EAN): 9783798508613 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although surgical and catheter-based revascularization techniques have substan- tially improved today`s therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance.
Описание: Das Buch enthalt Kapitel uber: M. B. Bottorff, W. E. Evans, Memphis, TN, USA: Uberwachung der Medikament-KonzentrationE. Truscheit, I. Hillebrand, B. Junge, L. Muller, W. Puls, D. D. Schmidt, Wuppertal, FRG: Inhibitoren der mikrobiellen alpha-Glucosidase: Chemie, Biochemie und potentielle therapeutische AnwendungenH. Will, Berlin-Buch, GDR: Plasminogen-Aktivatoren: Molekuleigenschaften, biologische Zellfunktion und klinische Anwendung
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