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Novel Apoptotic Regulators in Carcinogenesis, George G. Chen; Paul B.S. Lai


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Цена: 25155.00р.
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Автор: George G. Chen; Paul B.S. Lai
Название:  Novel Apoptotic Regulators in Carcinogenesis
ISBN: 9789400794931
Издательство: Springer
Классификация:





ISBN-10: 9400794932
Обложка/Формат: Paperback
Страницы: 300
Вес: 0.44 кг.
Дата издания: 21.09.2014
Язык: English
Издание: 2012 ed.
Иллюстрации: 30 tables, black and white; xii, 300 p.
Размер: 234 x 156 x 17
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Our recent understanding of the cellular and molecular defects and the regulation of the apoptotic signalling pathways has resulted in rationally designed anticancer strategies and the development of novel agents that regulates apoptosis. A comprehensive review of all apoptotic-related anticancer therapies is not the purpose of this book. However, in the volume of this book with 11 chapters, we have described a number of novel apoptotic regulators that have shown promising value and also great feasibility for cancer treatment. These novel agents either occur naturally or are chemically synthesized. While we are excited about the discovery and development of these novel apoptotic regulators as potential anticancer agents, a degree of caution should be always borne in mind when interpreting the success of preclinical pro-apoptotic candidates since potential problems inevitably lie ahead. These problems usually include target specificity, unanticipated toxicity, compound stability, formulation issues, pharmacokinetic and pharmacodynamic profiles. Nevertheless, we believe that this collection of 11 chapters by established leaders in the area of apoptosis will be of great interest to not only academics working in the field of cancer research and apoptosis but also pharmaceutical and pharmacological industries that . We are looking forward to the further development to push these potential agents toward clinical stage.
Дополнительное описание: Preface.-1 Apoptosis Inducer from Streblus asper Extracts for Cancer Chemoprevention.- 2 Apoptosis Induction by Nimbolide, a Limonoid from Azadirachta indica: Molecular Targets and Signaling Networks.- 3 Heterocyclics as inducers of apoptosis.- 4 Anthocya



Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases

Автор: Marek Los; Spencer B. Gibson
Название: Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
ISBN: 1489996893 ISBN-13(EAN): 9781489996893
Издательство: Springer
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Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer.

Hormonal Carcinogenesis V

Автор: Jonathan J. Li; Sara A. Li; Suresh Mohla; Henri Ro
Название: Hormonal Carcinogenesis V
ISBN: 1441923993 ISBN-13(EAN): 9781441923998
Издательство: Springer
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Цена: 38992.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Information gathered from cell-free systems, cell cultures, animal models, and human studies, together provide important insights to our understanding of hormonal cancer causation, development, and prevention; The emerging fields of colon, lung, and pancreatic cancers in relation to hormones are examined.

Hormonal Carcinogenesis V

Автор: Jonathan J. Li; Sara A. Li; Suresh Mohla; Henri Ro
Название: Hormonal Carcinogenesis V
ISBN: 0387690786 ISBN-13(EAN): 9780387690780
Издательство: Springer
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Цена: 38992.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Gathers information, from cell-free systems, cell cultures, animal models, and human studies, that provide important insights to our understanding of hormonal cancer causation, development, and prevention; the primary objective of these Symposia. This title emphasises on the two major endocrine-related cancers, that is, breast and prostate.

Chemical Carcinogenesis

Автор: Trevor M. Penning
Название: Chemical Carcinogenesis
ISBN: 1617797294 ISBN-13(EAN): 9781617797293
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Presenting the current advances in chemical carcinogenesis, this volume promotes the view that the chemical alteration of DNA is a route cause of many cancers. Topics include the multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action.

Apoptotic Pathways as Target for Novel Therapies in Cancer & Other Diseases

Автор: Los
Название: Apoptotic Pathways as Target for Novel Therapies in Cancer & Other Diseases
ISBN: 0387233849 ISBN-13(EAN): 9780387233840
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Поставка под заказ.

Описание: As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer.


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