Natural compounds as inducers of cell death, Marc Diederich; Karoline Noworyta
Автор: Andras Nagy; Kursad Turksen Название: Patient-Specific Induced Pluripotent Stem Cell Models ISBN: 1493930338 ISBN-13(EAN): 9781493930333 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases.
Автор: Andras Nagy; Kursad Turksen Название: Patient-Specific Induced Pluripotent Stem Cell Models ISBN: 149394973X ISBN-13(EAN): 9781493949731 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases.
Автор: Mikhail A. Nikiforov Название: Oncogene-Induced Senescence ISBN: 1493966685 ISBN-13(EAN): 9781493966684 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers in a single volume a unique collection of the state-of the-art experimental procedures utilized for the induction, detection, and modeling of this complex cellular program of oncogene-induced senescence. The book encompasses protocols for studying this multi-step program in human specimens and a variety of experimental models including cultured mammalian cells, laboratory mice, and Drosophila melanogaster, as well as offering a description of high throughput approaches. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Oncogene-Induced Senescence: Methods and Protocols represents a valuable asset for a wide audience of medical oncologists and researchers in the fields of oncology, molecular and cellular biology, biochemistry, and animal development.
Автор: Mark M. Kockx Название: Spontaneous and Induced Intima Formation in Blood Vessels ISBN: 3662224321 ISBN-13(EAN): 9783662224328 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Atherosclerosis, the most common disease in humans and also the main cause of death in the Western world, only develops after an intima is formed. This volume considers all aspects of intima formation based on results which had been obtained by studying three different models: - Spontaneous intima formation;
Автор: Jan Ponten Название: Spontaneous and Virus Induced Transformation in Cell Culture ISBN: 3709182603 ISBN-13(EAN): 9783709182604 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A. Definitions of Transformation in vitro When normal tissues or organs are explanted to conditions favoring the growth of cells as individual units ("cell culture"), the original cell population undergoes a large variety of modifications. Only a minority of the cells will thrive and multiply and within a rather short period of time, the complex composition of the original explant is replaced by a much simplified one of only a few recogniz- ably different cell types. With most organs fibroblast-like cells survive longest and outgrow other types. This is then a stable state of affairs for many gener- ations. This treatise will not discuss whether this simplification and stabilization represents selection of certain pre-existing cell types or a modification of cells into only a few recognizably different categories; for an excellent review see HARRIS. (1964). Table 1. Terminology Employed to Describe Transformations in vitro Type of transformation Essential features Irregular growth Lack of contact inhibition of cell membrane movement ("ruffled membranes") between juxtaposed cells Unrestrained growth Deficient inhibition of the cell cycle (mitosis) in a crowded culture Infinite growth Capacity of cells to undergo an infinite number of di- visions (formation of established cell lines) Cells may depart from this typical behavior in numerous ways involving for instance cellular morphology, immunology, chromosomes or metabolism. Such changes have, sometimes rather vaguely, been called "transformations". This is unprecise and the term "transformation" will here be used exclusively to indicate disturbances in cell growth related to neoplasia.
Автор: Who/Europe Название: Allergic Hypersensitivities Induced by Chemicals ISBN: 0849392268 ISBN-13(EAN): 9780849392269 Издательство: Taylor&Francis Рейтинг: Цена: 39811.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, commissioned by the World Health Organization (WHO) and written by international experts, provides consensus views on the most important issues related to allergic hypersensitivities
Автор: Michael B. A. Oldstone Название: Molecular Mimicry: Infection Inducing Autoimmune Disease ISBN: 3642421830 ISBN-13(EAN): 9783642421839 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Molecular Mimicry, Microbial Infection and Autoimmune Disease: Evolution of the Concept.- A Virus-Induced Molecular Mimicry Model of Multiple Sclerosis.- Suppression of Autoimmunity via Microbial Mimics of Altered Peptide Ligands.- Molecular and Cellular Mechanisms, Pathogenesis and Treatment of Insulin-Dependent Diabetes Obtained Through Study of a Transgenic Model of Molecular Mimicry.- Trypanosoma cruzi-Induced Molecular Mimicry and Chagas' Disease.- HTLV-1-Induced Molecular Mimicry in Neurologic Disease.- Molecular Mimicry: Anti-DNA Antibodies Bind Microbial and Non-Nucleic Acid Self Antigens.- The Structural Interactions Between T-Cell Receptors and MHC/Peptide Complexes Place Physical Limits on Self-Nonself Discrimination.- Subject Index
Описание: This book examines irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposure, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for allergic and irritant reactions.
Автор: Mittelman David Название: Stress-Induced Mutagenesis ISBN: 1461462797 ISBN-13(EAN): 9781461462798 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers pathways of stress-induced mutagenesis, which may yield models for genome instability underlying some cancers and genetic diseases, resistance to chemotherapeutic and antibiotic drugs, pathogenicity of microbes, and other important processes.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
