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Epigenetic Alterations in Oncogenesis, Adam R. Karpf


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Цена: 27950.00р.
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Автор: Adam R. Karpf
Название:  Epigenetic Alterations in Oncogenesis
ISBN: 9781489985583
Издательство: Springer
Классификация:

ISBN-10: 1489985581
Обложка/Формат: Paperback
Страницы: 348
Вес: 0.51 кг.
Дата издания: 15.10.2014
Серия: Advances in experimental medicine and biology
Язык: English
Издание: 2012 ed.
Иллюстрации: Xvi, 348 p.
Размер: 234 x 156 x 19
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.
Дополнительное описание: Preface.- Section I: Epigenetic Marks and Mechanisms.- DNA methyltransferases (DNMTs), DNA damage repair, and cancer.- DNA hypomethylation and hemimethylation in cancer.- Ten Eleven Translocation (TET) Enzymes and 5-hydroxymethylation in Mammalian Develop



DNA Alterations in Lynch Syndrome

Автор: Matja? Vogelsang
Название: DNA Alterations in Lynch Syndrome
ISBN: 9400765967 ISBN-13(EAN): 9789400765962
Издательство: Springer
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Цена: 20896.00 р.
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Описание: This book surveys the genetic and epigenetic basis of Lynch syndrome, evaluating its clinical features and analyzing molecular tools for identifying mutations responsible for the syndrome; includes functional assays for assessing identified mutations.

Cell Growth and Oncogenesis.1998

Автор: Bannasch
Название: Cell Growth and Oncogenesis.1998
ISBN: 3764357274 ISBN-13(EAN): 9783764357276
Издательство: Springer
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Цена: 29209.00 р.
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Описание: This volume describes the role of specific genes and refers to the inetracellular changes that occur in tumorgenic cells. It contains the latest developments on the regulation of cell growth in normal and carcinogenic tissues.

Mechanisms of Oncogenesis

Автор: Coppola
Название: Mechanisms of Oncogenesis
ISBN: 9048137241 ISBN-13(EAN): 9789048137244
Издательство: Springer
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Цена: 34799.00 р.
Наличие на складе: Поставка под заказ.

Описание: This book offers a comprehensive update on mechanisms of tumorigenesis. The first portion discusses pediatric cancer, the influence of environmental factors and oncogene activity in tumorigenesis; the second portion is structured by organ site for easy access.

MicroRNAs: Key Regulators of Oncogenesis

Автор: Sadegh Babashah
Название: MicroRNAs: Key Regulators of Oncogenesis
ISBN: 3319376136 ISBN-13(EAN): 9783319376134
Издательство: Springer
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Цена: 20896.00 р.
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Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.

MicroRNAs: Key Regulators of Oncogenesis

Автор: Sadegh Babashah
Название: MicroRNAs: Key Regulators of Oncogenesis
ISBN: 3319037242 ISBN-13(EAN): 9783319037240
Издательство: Springer
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Цена: 26122.00 р.
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Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.

Epigenetic Cancer Therapy

Автор: Steven Gray
Название: Epigenetic Cancer Therapy
ISBN: 0128002069 ISBN-13(EAN): 9780128002063
Издательство: Elsevier Science
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Цена: 17517.00 р.
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Описание:

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.

The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).

The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.

DNA Alterations in Lynch Syndrome

Автор: Matja? Vogelsang
Название: DNA Alterations in Lynch Syndrome
ISBN: 9401784582 ISBN-13(EAN): 9789401784580
Издательство: Springer
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Цена: 18284.00 р.
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Описание: This book surveys the genetic and epigenetic basis of Lynch syndrome, evaluating its clinical features and analyzing molecular tools for identifying mutations responsible for the syndrome; includes functional assays for assessing identified mutations.

Chromosomal Alterations

Автор: G?nter Obe; Vijayalaxmi
Название: Chromosomal Alterations
ISBN: 3642090591 ISBN-13(EAN): 9783642090592
Издательство: Springer
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Цена: 36570.00 р.
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Описание: The book provides a comprehensive review of basic and applied aspects of cytogenetics and thus is of intense interest to all those interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.

Radiation Carcinogenesis and DNA Alterations

Автор: Frederic J. Burns
Название: Radiation Carcinogenesis and DNA Alterations
ISBN: 1468452711 ISBN-13(EAN): 9781468452716
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Since breakage of the DNA is one of the principal ways that ion- izing radiation affects mammalian cells, these new molecular ideas sug- gest ways that radiation-induced DNA breaks might be involved as initial events in carcinogenesis.

Chromosomal Alterations

Автор: G?nter Obe; Adayapalam T. Natarajan
Название: Chromosomal Alterations
ISBN: 3642788890 ISBN-13(EAN): 9783642788895
Издательство: Springer
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Цена: 15672.00 р.
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Описание: With contributions by numerous experts

Epigenetic Advancements in Cancer

Автор: Manoj K. Mishra; Kumar S. Bishnupuri
Название: Epigenetic Advancements in Cancer
ISBN: 3319249495 ISBN-13(EAN): 9783319249490
Издательство: Springer
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Цена: 19591.00 р.
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Описание: 1. Role of DNA methylation in the progression and clearance of cancer.- 2. Epigenetical role for RNA in cancer progression.- 3. Epigenetics and its role in prostate cancer.- 4. Epigenetics and ovarian cancer.- 5. Epigenetics and breast cancer.- 6. Epigenetics and thyroid cancer.- 7. Epigenetics and intestinal cancer.- 8. Epigenetics and lung cancer.- 9. Epigenetics and renal cancer.- 10. Epigenetics and cervical cancer.- 11. Epigenetical markers in cancer.- 12. Epigenetical role in pancreatic cancer.

Epigenetic Mechanisms in Cancer

Автор: Saldanha, Sabita
Название: Epigenetic Mechanisms in Cancer
ISBN: 0128095520 ISBN-13(EAN): 9780128095522
Издательство: Elsevier Science
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Цена: 19875.00 р.
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Описание: Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offer a unique evaluation of signature differences in of childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.

  • Offers broad coverage that is applicable to audiences in various area of cancer research - population studies, diagnostics, prognosis, prediction, therapy, risk, etc.
  • Provides critical review analysis of the topics that will clarify and delineate the potential roles of epigenetic signatures in cancer management
  • Covers basic, as well as, clinical areas of epigenetic mechanisms in tumorigenesis
  • Features contributions by leading experts in the field
  • Provides comprehensive coverage of current epigenetic signatures involved in the etiology of various cancers and miRNAs

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