Автор: G?nter Obe; Adayapalam T. Natarajan Название: Chromosomal Alterations ISBN: 3642788890 ISBN-13(EAN): 9783642788895 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Gerald R. Reeck Название: Chromosomal Proteins and Gene Expression ISBN: 1468476173 ISBN-13(EAN): 9781468476170 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book stems from an Advanced Study Institute on Chromo- somal Proteins and Gene Expression that was held in Sitges, Spain, on September 17-26, 1984. Furthermore, many participants found that exchanging ideas outside organized sessions was among the most rewarding aspects of the course.
Описание: Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting.
Автор: Greg Davis; Kevin J. Kayser Название: Chromosomal Mutagenesis ISBN: 161737833X ISBN-13(EAN): 9781617378331 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In Chromosomal Mutagenesis, a team of experts provide a variety of chromosomal manipulation techniques, including insertional gene disruptions, gene knockouts, stimulated homologous recombination techniques and other novel tools, for both prokaryotic and eukaryotic organisms, and attempt to expand the genetic toolbox beyond model organisms.
Автор: Janet D. Rowley; Michelle M. Le Beau; Terence H. R Название: Chromosomal Translocations and Genome Rearrangements in Cancer ISBN: 331919982X ISBN-13(EAN): 9783319199825 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Matja? Vogelsang Название: DNA Alterations in Lynch Syndrome ISBN: 9400765967 ISBN-13(EAN): 9789400765962 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys the genetic and epigenetic basis of Lynch syndrome, evaluating its clinical features and analyzing molecular tools for identifying mutations responsible for the syndrome; includes functional assays for assessing identified mutations.
Автор: Adam R. Karpf Название: Epigenetic Alterations in Oncogenesis ISBN: 1489985581 ISBN-13(EAN): 9781489985583 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.
Автор: Frank J. III Rauscher; Peter K. Vogt Название: Chromosomal Translocations and Oncogenic Transcription Factors ISBN: 3642644244 ISBN-13(EAN): 9783642644245 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. This volume gives insights into how normal programs of gene expression can be subverted by the action of single transcription factors resulting in a specific tumor type.
Автор: B. Michael Ghadimi; Thomas Ried Название: Chromosomal Instability in Cancer Cells ISBN: 3319202901 ISBN-13(EAN): 9783319202907 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification.
Автор: G?nter Obe; A.T. Natarajan Название: Chromosomal Aberrations ISBN: 3642756840 ISBN-13(EAN): 9783642756849 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chromosomale Mutationen sind eine der m-glichen Ursachen f}r Ver{nderungen der Erbinformation. Neben grunds{tzlichen As- pekten, wie Reparaturmechanismen der Zelle oder Ursachen von Chromosomenver{nderungen, werden angewandte Aspekte, z.B. Chromosomen als Testindikatoren der Toxizit{t, behandelt.
Автор: B. Michael Ghadimi; Thomas Ried Название: Chromosomal Instability in Cancer Cells ISBN: 3319349627 ISBN-13(EAN): 9783319349626 Издательство: Springer Рейтинг: Цена: 11179.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer.
Описание: This guide discusses chromosomal abnormalities and how best to report and communicate lab findings in research and clinical settings. Providing a standard approach to writing cytogenetic laboratory reports, the guide further covers useful guidance on implementing International System for Human Cytogenetic Nomenclature in reports.
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