Chromosomal Mutagenesis, Greg Davis; Kevin J. Kayser
Автор: G. Shashidhar Pai Название: Handbook of Chromosomal Syndromes ISBN: 047137217X ISBN-13(EAN): 9780471372172 Издательство: Wiley Рейтинг: Цена: 26762.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive reference provides a pictorial and descriptive account of approximately 200 chromosomal aneuploidy syndromes. It focuses exclusively on clinical syndromes due to chromosomal abnormalities.
Описание: This guide discusses chromosomal abnormalities and how best to report and communicate lab findings in research and clinical settings. Providing a standard approach to writing cytogenetic laboratory reports, the guide further covers useful guidance on implementing International System for Human Cytogenetic Nomenclature in reports.
Автор: Thomas Liehr Название: Benign & Pathological Chromosomal Imbalances, ISBN: 0124046312 ISBN-13(EAN): 9780124046313 Издательство: Elsevier Science Рейтинг: Цена: 11620.00 р. Наличие на складе: Поставка под заказ.
Описание: Benign & Pathological Chromosomal Imbalances systematically clarifies the disease implications of cytogenetically visible copy number variants (CG-CNV) using cytogenetic assessment of heterochromatic or euchromatic DNA variants. While variants of several megabasepair can be present in the human genome without clinical consequence, visually distinguishing these benign areas from disease implications does not always occur to practitioners accustomed to costly molecular profiling methods such as FISH, aCGH, and NGS. . As technology-driven approaches like FISH and aCGH have yet to achieve the promise of universal coverage or cost efficacy to sample investigated, deep chromosome analysis and molecular cytogenetics remains relevant for technology translation, study design, and therapeutic assessment. Knowledge of the rare but recurrent rearrangements unfamiliar to practitioners saves time and money for molecular cytogeneticists and genetics counselors, helping to distinguish benign from harmful CG-CNV. It also supports them in deciding which molecular cytogenetics tools to deploy.
Автор: G?nter Obe; Adayapalam T. Natarajan Название: Chromosomal Alterations ISBN: 3642788890 ISBN-13(EAN): 9783642788895 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Reeves Название: In Vitro Mutagenesis ISBN: 1493964704 ISBN-13(EAN): 9781493964703 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In vitro mutagenesis remains a critical experimental approach for investigating gene and protein function at the cellular level. This volume provides a wide variety of updated and novel approaches for performing in vitro mutagenesis using such methods as genome editing, transposon (Tn) mutagenesis, site-directed, and random mutagenesis. In Vitro Mutagenesis: Methods and Protocols guides readers through methods for gene and genome editing, practical bioinformatics approaches for identifying mutagenesis targets, and novel site-directed and random mutagenesis approaches aimed at gaining a better understanding of protein-protein and protein-cofactor interactions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, In Vitro Mutagenesis: Methods and Protocols aims to provide a highly accessible and practical manual for current and future molecular biology researchers, from the beginner practitioner to the advanced investigator in fields such as molecular genetics, biochemistry, and biochemical and metabolic engineering.
Автор: Shondra M. Pruett-Miller Название: Chromosomal Mutagenesis ISBN: 1493918613 ISBN-13(EAN): 9781493918614 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols.
Автор: Shondra M. Pruett-Miller Название: Chromosomal Mutagenesis ISBN: 1493955411 ISBN-13(EAN): 9781493955411 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols.
Автор: Janet D. Rowley; Michelle M. Le Beau; Terence H. R Название: Chromosomal Translocations and Genome Rearrangements in Cancer ISBN: 331919982X ISBN-13(EAN): 9783319199825 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: B. Michael Ghadimi; Thomas Ried Название: Chromosomal Instability in Cancer Cells ISBN: 3319202901 ISBN-13(EAN): 9783319202907 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification.
Автор: B. Michael Ghadimi; Thomas Ried Название: Chromosomal Instability in Cancer Cells ISBN: 3319349627 ISBN-13(EAN): 9783319349626 Издательство: Springer Рейтинг: Цена: 11179.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer.
Автор: G?nter Obe; Vijayalaxmi Название: Chromosomal Alterations ISBN: 3642090591 ISBN-13(EAN): 9783642090592 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book provides a comprehensive review of basic and applied aspects of cytogenetics and thus is of intense interest to all those interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.
Автор: Frank J. III Rauscher; Peter K. Vogt Название: Chromosomal Translocations and Oncogenic Transcription Factors ISBN: 3642644244 ISBN-13(EAN): 9783642644245 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. This volume gives insights into how normal programs of gene expression can be subverted by the action of single transcription factors resulting in a specific tumor type.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
