Mechanosensing and Mechanochemical Transduction in Extracellular Matrix, S.S. Cowin; Frederick H. Silver

Автор: Masaki Noda
Название: Mechanosensing Biology
ISBN: 4431546464 ISBN-13(EAN): 9784431546467
Издательство: Springer
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Описание: Covering topics such as gravity and tissues and disuse osteoporosis, the book provides up-to-date information on cutting-edge advancements in the field of mechanobiology. It also offers a timely contribution to research major problems in contemporary society.

Автор: Friedrich Marks, Ursula Klingmuller, Karin Muller- Decker
Название: Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction
ISBN: 0815345348 ISBN-13(EAN): 9780815345343
Издательство: Taylor&Francis
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Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Автор: Daniel Mooradian
Название: Extracellular Matrix-derived Medical Implants in Clinical Medicin
ISBN: 0081001665 ISBN-13(EAN): 9780081001660
Издательство: Elsevier Science
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Описание: "

Extracellular Matrix-Derived Implants in Clinical Medicine "comprehensively covers the emergence of tissue engineering and regenerative medicine over the past few decades, along with discussions of continuous funding and research.

The book provides a state-of-the-art review of this increasingly important technology and how it is translating from bench to bedside. Part One of the book looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological, while Part Two examines the challenges in harvesting, processing, and manufacturing of extracellular matrices, with a final section reviewing the international regulatory environment and economics of tissue-based products.
Addresses issues of tissue engineering and regenerative medicine from a biomaterials industry perspectiveLooks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurologicalExamines the challenges in harvesting, processing, and manufacturing of extracellular matricesReviews the international regulatory environment and economics of tissue-based products

Автор: Douglas W. DeSimone; Robert Mecham
Название: Extracellular Matrix in Development
ISBN: 3642427405 ISBN-13(EAN): 9783642427404
Издательство: Springer
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Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

Автор: Fred W. Keeley; Robert Mecham
Название: Evolution of Extracellular Matrix
ISBN: 3642430376 ISBN-13(EAN): 9783642430374
Издательство: Springer
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Описание: This volume examines how the major ECM components evolved over time to fill their specific roles found in modern organisms. Coverage includes structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes.

Автор: Jennie B. Leach; Elizabeth M. Powell
Название: Extracellular Matrix
ISBN: 1493946870 ISBN-13(EAN): 9781493946877
Издательство: Springer
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Описание:

Part I: Native Tissue

1. Immunohistochemical Characterization of Brain Neural and Vascular Basement Membranes

Zhen Huang

2. The Use of Synaptic Basal Lamina and Its Components to Identify Sites of Recent Morphological Alterations at Mammalian Neuromuscular Junctions

Young il Lee and Yue Li

3. Perineuronal Nets: A Special Structure in the Central Nervous System Extracellular Matrix

Jessica C.F. Kwok, Simona Foscarin, and James W. Fawcett

Part II: In Vitro Models

4. Isolation of Perinatal Mouse Cerebral Cortical Astrocytes

Rolicia F. Martin and Elizabeth M. Powell

5. Techniques for Examining the Effect of Substratum Bound Proteoglycans on Neurite Outgrowth In Vitro

Justin A. Beller, Thomas M. Hering, and Diane M. Snow

6. High-Throughput Quantitative Assay for Analyzing Neurite Outgrowth on a Uniform Substratum: The Cell-Substratum Assay

Justin A. Beller, Thomas M. Hering, and Diane M. Snow

7. Extracellular Matrix Components as a Substrate for Outgrowing Motoneurons

Rebecca Conrad, Alice Klausmeyer, Teresa Tsai, Andreas Faissner, and Stefan Wiese

8. Replicating the In Vivo Environment: Organotypic and Submerged Three-Dimensional Culture Methods

Cйline Plachez and Elizabeth M. Powell

9. Culturing Neurons, Glia, and Progenitor Cells in Three-Dimensional Hydrogels

Swarnalatha Balasubramanian, Elizabeth M. Powell, and Jennie B. Leach

10. Investigating Cell-ECM Interactions and ECM Synthesis in Three-Dimensional Hydrogels

Swarnalatha Balasubramanian, Elizabeth M. Powell, and Jennie B. Leach

Part III: Injury, Degeneration, and Regeneration

11. Characterization and Analysis of Extracellular Matrix in Malignant Brain Tumors and Their Cellular Derivatives

Maksim Sinyuk, Justin D. Lathia, and Mariano S. Viapiano

12. Chondroitinase Gene Therapy for Spinal Cord Injury

Jianli Hu, Gabrielle M. Curinga, and George M. Smith

13. Modulation of Neural Stem Cell Expressed Extracellular Matrix (ECM) by Targeting Glycosyltransferases

Eva Hennen and Andreas Faissner

Part IV: Therapeutics and Engineered Systems

14. Evaluating the Spatial and Temporal Protein Production in Neural Tissue Engineering Constructs In Vitro

Caroline P. Addington, Christine Pauken, and Sarah E. Stabenfeldt

15. Cultivation and Imaging of Astrocytes on Protein-Coated Fluorescent Topographies Constructed from Aligned PLLA Electrospun Fibers

Jonathan M. Zuidema, Marнa C. Hyzinski-Garcнa, Alexander A. Mongin, and Ryan J. Gilbert

16. Engineered Microdevices to Study and Manipulate Neural Stem Cell Chemotaxis

Hui Xu and Sarah C. Heilshorn

17. Hydrolytically Degradable Polyethylene Glycol (PEG) Hydrogel: Synthesis, Gel Formation, and Characterization

Silviya Petrova Zustiak.

Автор: Fern?ndez Ruiz
Название: Extracellular Potentials in the Hippocampus
ISBN: 3319410385 ISBN-13(EAN): 9783319410388
Издательство: Springer
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Автор: Roy Sillitoe
Название: Extracellular Recording Approaches
ISBN: 149397548X ISBN-13(EAN): 9781493975488
Издательство: Springer
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Цена: 13974.00 р.
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This volume presents techniques and recently developments in extracellular recording. The chapters in this book explore topics such as mouse, rat and zebrafish models; extracellular recordings on human cognition; single-unit recordings and multi-electrode arrays; and recordings in perinatal and early developing mice. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and authoritative, Extracellular Recording Approaches is a valuable resource that provides readers with up-to-date applications and methods to study brain regions involved in sensory, motor, and cognitive functions.

Автор: Herbert Waldmann; G. Dorman; P.J. Hergenrother; C.
Название: Bioorganic Chemistry of Biological Signal Transduction
ISBN: 3662146975 ISBN-13(EAN): 9783662146972
Издательство: Springer
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Автор: Raoul Ranjeva; Alain M. Boudet
Название: Signal Perception and Transduction in Higher Plants
ISBN: 3642839762 ISBN-13(EAN): 9783642839764
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Proceedings of the NATO Advanced Research Workshop on Signal Perception and Transduction in Higher Plants held in Toulouse, France, July 9 - 13, 1989

Автор: DeSimone Douglas W
Название: Extracellular Matrix in Development
ISBN: 3642359345 ISBN-13(EAN): 9783642359347
Издательство: Springer
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Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

Автор: Struther Arnott; D. A. Rees; E. R. Morris
Название: Molecular Biophysics of the Extracellular Matrix
ISBN: 1461295939 ISBN-13(EAN): 9781461295938
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, link- ages, and sequences is followed by investigations of molecu- lar architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteo- glycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of three- dimensional shapes and intermolecular associations. For- tunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction anal- ysis of hydrated films, nuclear magnetic resonance spectro- scopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitiv- ity to environment (especially associated cations), and their modes of interaction that could be relevant to super- molecular assemblies in biological milieux. For these rea- sons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay be- tween biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society.