Evolution of Extracellular Matrix, Fred W. Keeley; Robert Mecham

Автор: Jennie B. Leach; Elizabeth M. Powell
Название: Extracellular Matrix
ISBN: 1493946870 ISBN-13(EAN): 9781493946877
Издательство: Springer
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Цена: 13275.00 р.
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Описание:

Part I: Native Tissue

1. Immunohistochemical Characterization of Brain Neural and Vascular Basement Membranes

Zhen Huang

2. The Use of Synaptic Basal Lamina and Its Components to Identify Sites of Recent Morphological Alterations at Mammalian Neuromuscular Junctions

Young il Lee and Yue Li

3. Perineuronal Nets: A Special Structure in the Central Nervous System Extracellular Matrix

Jessica C.F. Kwok, Simona Foscarin, and James W. Fawcett

Part II: In Vitro Models

4. Isolation of Perinatal Mouse Cerebral Cortical Astrocytes

Rolicia F. Martin and Elizabeth M. Powell

5. Techniques for Examining the Effect of Substratum Bound Proteoglycans on Neurite Outgrowth In Vitro

Justin A. Beller, Thomas M. Hering, and Diane M. Snow

6. High-Throughput Quantitative Assay for Analyzing Neurite Outgrowth on a Uniform Substratum: The Cell-Substratum Assay

Justin A. Beller, Thomas M. Hering, and Diane M. Snow

7. Extracellular Matrix Components as a Substrate for Outgrowing Motoneurons

Rebecca Conrad, Alice Klausmeyer, Teresa Tsai, Andreas Faissner, and Stefan Wiese

8. Replicating the In Vivo Environment: Organotypic and Submerged Three-Dimensional Culture Methods

Cйline Plachez and Elizabeth M. Powell

9. Culturing Neurons, Glia, and Progenitor Cells in Three-Dimensional Hydrogels

Swarnalatha Balasubramanian, Elizabeth M. Powell, and Jennie B. Leach

10. Investigating Cell-ECM Interactions and ECM Synthesis in Three-Dimensional Hydrogels

Swarnalatha Balasubramanian, Elizabeth M. Powell, and Jennie B. Leach

Part III: Injury, Degeneration, and Regeneration

11. Characterization and Analysis of Extracellular Matrix in Malignant Brain Tumors and Their Cellular Derivatives

Maksim Sinyuk, Justin D. Lathia, and Mariano S. Viapiano

12. Chondroitinase Gene Therapy for Spinal Cord Injury

Jianli Hu, Gabrielle M. Curinga, and George M. Smith

13. Modulation of Neural Stem Cell Expressed Extracellular Matrix (ECM) by Targeting Glycosyltransferases

Eva Hennen and Andreas Faissner

Part IV: Therapeutics and Engineered Systems

14. Evaluating the Spatial and Temporal Protein Production in Neural Tissue Engineering Constructs In Vitro

Caroline P. Addington, Christine Pauken, and Sarah E. Stabenfeldt

15. Cultivation and Imaging of Astrocytes on Protein-Coated Fluorescent Topographies Constructed from Aligned PLLA Electrospun Fibers

Jonathan M. Zuidema, Marнa C. Hyzinski-Garcнa, Alexander A. Mongin, and Ryan J. Gilbert

16. Engineered Microdevices to Study and Manipulate Neural Stem Cell Chemotaxis

Hui Xu and Sarah C. Heilshorn

17. Hydrolytically Degradable Polyethylene Glycol (PEG) Hydrogel: Synthesis, Gel Formation, and Characterization

Silviya Petrova Zustiak.

Автор: Robert Mecham
Название: The Extracellular Matrix: an Overview
ISBN: 364226719X ISBN-13(EAN): 9783642267192
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Covering a wide spectrum of topics including collagen types and the role of the ECM in human disease and pathogenesis, this volume is a timely overview of the structure, regulation, and function of the major macromolecules that form the extracellular matrix.

Автор: DeSimone Douglas W
Название: Extracellular Matrix in Development
ISBN: 3642359345 ISBN-13(EAN): 9783642359347
Издательство: Springer
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Цена: 26122.00 р.
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Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

Автор: Elizabeth D. Hay
Название: Cell Biology of Extracellular Matrix
ISBN: 1461282268 ISBN-13(EAN): 9781461282266
Издательство: Springer
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Цена: 16979.00 р.
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Описание: At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears.

Автор: Rolf A. Brekken; Dwayne Stupack
Название: Extracellular Matrix in Tumor Biology
ISBN: 3319609068 ISBN-13(EAN): 9783319609065
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.

Автор: S.S. Cowin; Frederick H. Silver
Название: Mechanosensing and Mechanochemical Transduction in Extracellular Matrix
ISBN: 1489986162 ISBN-13(EAN): 9781489986160
Издательство: Springer
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Цена: 9794.00 р.
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Описание: The only single authored text on biological polymers available for bioengineering and biomedical engineering students. The book describes the structure of polymers and how these molecules are put together to make the tissues of the body.

Автор: Roy Zent; Ambra Pozzi
Название: Cell-Extracellular Matrix Interactions in Cancer
ISBN: 1489981128 ISBN-13(EAN): 9781489981127
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book describes how extracellular matrix components (ECM) create a niche for tumor formation. It also discusses the contribution of ECM components and their respective receptors in the development and spread of cancer.

Автор: Douglas W. DeSimone; Robert Mecham
Название: Extracellular Matrix in Development
ISBN: 3642427405 ISBN-13(EAN): 9783642427404
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

Автор: Struther Arnott; D. A. Rees; E. R. Morris
Название: Molecular Biophysics of the Extracellular Matrix
ISBN: 1461295939 ISBN-13(EAN): 9781461295938
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, link- ages, and sequences is followed by investigations of molecu- lar architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteo- glycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of three- dimensional shapes and intermolecular associations. For- tunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction anal- ysis of hydrated films, nuclear magnetic resonance spectro- scopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitiv- ity to environment (especially associated cations), and their modes of interaction that could be relevant to super- molecular assemblies in biological milieux. For these rea- sons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay be- tween biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society.