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Ghrelin in Health and Disease, Roy G. Smith; Michael O. Thorner


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Автор: Roy G. Smith; Michael O. Thorner
Название:  Ghrelin in Health and Disease
ISBN: 9781627038799
Издательство: Springer
Классификация:





ISBN-10: 1627038795
Обложка/Формат: Paperback
Страницы: 290
Вес: 0.43 кг.
Дата издания: 09.11.2014
Серия: Contemporary Endocrinology
Язык: English
Издание: 2012 ed.
Иллюстрации: 7 tables, black and white; xiv, 290 p.
Размер: 234 x 156 x 16
Читательская аудитория: General (us: trade)
Основная тема: Medicine & Public Health
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
Дополнительное описание: Ghrelin: A History of Its Discovery.- Enzymatic Processing of Ghrelin Precursor.- Ghrelin’s Novel Signaling in Islet b-Cells to Inhibit Insulin Secretion and Its Blockade As a Promising Strategy to Treat Type 2 Diabetes.- Gastric Ghrelin in the Regulation



Stem Cell Biology in Health and Disease 2010

Автор: DittmarDittmar
Название: Stem Cell Biology in Health and Disease 2010
ISBN: 9048130395 ISBN-13(EAN): 9789048130399
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This volume examines the dual role of stem cells in health and disease. It details strategies on the use of embryonic stem cells and embryonic-like stem cells in regenerative medical purposes as well as strategies on the elimination of cancer stem cells.

Central Functions of the Ghrelin Receptor

Автор: Jeanelle Portelli; Ilse Smolders
Название: Central Functions of the Ghrelin Receptor
ISBN: 1493908227 ISBN-13(EAN): 9781493908226
Издательство: Springer
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Цена: 23757.00 р.
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Описание: The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others. The functions of the ghrelin receptor in the central nervous system are numerous and are still being explored. In this book we specifically focus on the various roles of the ghrelin receptor in the central nervous system. In a first set of chapters, the book will focus on the discovery and the properties of this intriguing constitutively active G-protein coupled receptor, on its multiple intracellular transduction mechanisms and the various subtypes of the currently known ghrelin receptor complexes. Next, the book will elaborate on the mitochondrial mechanisms regulated by the ghrelin receptor, its role in feeding and drug addictive mechanisms, memory, sleep and arousal. The final chapters focus on the potential of this receptor as a target for the treatment of neurological disorders including Parkinson’s disease, epilepsy, anxiety and depression.

Central Functions of the Ghrelin Receptor

Автор: Jeanelle Portelli; Ilse Smolders
Название: Central Functions of the Ghrelin Receptor
ISBN: 1493955349 ISBN-13(EAN): 9781493955343
Издательство: Springer
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Цена: 19589.00 р.
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Описание: The Ghrelin receptor was identified before its natural ligand ghrelin.

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Автор: Lyte, Mark, Cryan, John F. (Eds.)
Название: Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease
ISBN: 1493908960 ISBN-13(EAN): 9781493908967
Издательство: Springer
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Цена: 30745.00 р.
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Описание: The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host ("us").

Paraoxonase (PON1) in Health and Disease

Автор: Lucio G. Costa; Clement E. Furlong
Название: Paraoxonase (PON1) in Health and Disease
ISBN: 1461353580 ISBN-13(EAN): 9781461353584
Издательство: Springer
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Цена: 13974.00 р.
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Описание: The paraoxonase or PON family of genes resides on human chromosome 7q2t-22 in the order PONt, PON3 and PON2. PONt was one of the early genes identified as an environmentally relevant gene, in that it is important in determining an individual`s sensitivity or resistance to exposure from specific organophosphorus (OP) insecticides.

Amino Acid Availability and Brain Function in Health and Disease

Автор: Gerald Huether
Название: Amino Acid Availability and Brain Function in Health and Disease
ISBN: 3642731775 ISBN-13(EAN): 9783642731778
Издательство: Springer
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Цена: 22203.00 р.
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Описание: Proceedings of the NATO Advanced Research Workshop on Amino Acid Availability and Brain Function in Health and Disease held in Gottingen, FRG, September 14-18, 1987


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