Central Functions of the Ghrelin Receptor, Jeanelle Portelli; Ilse Smolders

Автор: Jeanelle Portelli; Ilse Smolders
Название: Central Functions of the Ghrelin Receptor
ISBN: 1493908227 ISBN-13(EAN): 9781493908226
Издательство: Springer
Рейтинг:
Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others. The functions of the ghrelin receptor in the central nervous system are numerous and are still being explored. In this book we specifically focus on the various roles of the ghrelin receptor in the central nervous system. In a first set of chapters, the book will focus on the discovery and the properties of this intriguing constitutively active G-protein coupled receptor, on its multiple intracellular transduction mechanisms and the various subtypes of the currently known ghrelin receptor complexes. Next, the book will elaborate on the mitochondrial mechanisms regulated by the ghrelin receptor, its role in feeding and drug addictive mechanisms, memory, sleep and arousal. The final chapters focus on the potential of this receptor as a target for the treatment of neurological disorders including Parkinson’s disease, epilepsy, anxiety and depression.

Автор: Ying Xia
Название: Neural Functions of the Delta-Opioid Receptor
ISBN: 3319254936 ISBN-13(EAN): 9783319254937
Издательство: Springer
Рейтинг:
Цена: 28734.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book is the first to summarize the progress of research on neural functions of the the delta opioid receptor (DOR) to date. The book will provide a comprehensive overview of the current state of DOR research and provide a blueprint for future directions.ГЇВїВЅ

Автор: Vincent Laudet
Название: The Nuclear Receptor FactsBook,
ISBN: 0124377351 ISBN-13(EAN): 9780124377356
Издательство: Elsevier Science
Рейтинг:
Цена: 12464.00 р.
Наличие на складе: Поставка под заказ.

Описание: Devoted to nuclear receptors, this work presents an introduction and describes the mode of action of the receptors in general. It also contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure; Isolation; DNA binding properties; Ligands; Expression; Target genes; Knockouts; and more.

Автор: Antonius M. VanDongen
Название: Biology of the NMDA Receptor
ISBN: 1420044141 ISBN-13(EAN): 9781420044140
Издательство: Taylor&Francis
Рейтинг:
Цена: 29093.00 р.
Наличие на складе: Поставка под заказ.

Описание: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. This book brings together virtually various players in this field.

Автор: Alan A. Boulton; Glen B. Baker; Pavel D. Hrdina
Название: Receptor Binding
ISBN: 1489941282 ISBN-13(EAN): 9781489941282
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Marie-Paule Lefranc
Название: The T Cell Receptor FactsBook,
ISBN: 0124413528 ISBN-13(EAN): 9780124413528
Издательство: Elsevier Science
Рейтинг:
Цена: 13551.00 р.
Наличие на складе: Поставка под заказ.

Описание: This is a reference for all functional and ORF T-cell receptor genes. Introductory chapters provide up-to-date information on T-cell receptor structural and biological properties, chain synthesis, gene chromosomal localization, and organization of the TRA, TRB, TRG and TRD loci. This is followed by entries on all 168 functional and ORF variable, diversity, joining and constant genes, and a complete overview of the potential repertoire of the human T-cell receptor alpha, beta, gamma and delta loc

Автор: Rafael Luj?n; Francisco Ciruela
Название: Receptor and Ion Channel Detection in the Brain
ISBN: 149393063X ISBN-13(EAN): 9781493930630
Издательство: Springer
Рейтинг:
Цена: 22203.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Receptor and Ion Channel Detection in the Brain provides state-of-the-art and up-to-date methodological information on molecular, neuroanatomical and functional techniques that are currently used to study neurotransmitter receptors and ion channels in the brain.

Автор: Curtis A. Machida
Название: Adrenergic Receptor Protocols
ISBN: 1489941568 ISBN-13(EAN): 9781489941565
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Adrenergic Receptor Protocols consists of 35 chapters dealing with va- ous aspects of adrenergic receptor analyses, including the use of genetic, RNA, protein expression, transactivator, second messenger, immunocytochemical, electrophysiological, transgenic, and in situ hybridization approaches.

Автор: Roy G. Smith; Michael O. Thorner
Название: Ghrelin in Health and Disease
ISBN: 1627038795 ISBN-13(EAN): 9781627038799
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.