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Molecular Biology of the SARS-Coronavirus, Sunil K. Lal


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Автор: Sunil K. Lal
Название:  Molecular Biology of the SARS-Coronavirus
ISBN: 9783642424359
Издательство: Springer
Классификация:




ISBN-10: 364242435X
Обложка/Формат: Paperback
Страницы: 328
Вес: 0.48 кг.
Дата издания: 14.11.2014
Язык: English
Издание: 2010 ed.
Иллюстрации: Xiii, 328 p.
Размер: 234 x 156 x 18
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: SARS was the ?rst new plague of the twenty-?rst century. Within months, it spread worldwide from its “birthplace” in Guangdong Province, China, affecting over 8,000 people in 25 countries and territories across ?ve continents. SARS exposed the vulnerability of our modern globalised world to the spread of a new emerging infection. SARS (or a similar new emerging disease) could neither have spread so rapidly nor had such a great global impact even 50 years ago, and arguably, it was itself a product of our global inter-connectedness. Increasing af?uence and a demand for wild-game as exotic food led to the development of large trade of live animal and game animal markets where many species of wild and domestic animals were co-housed, providing the ideal opportunities for inter-species tra- mission of viruses and other microbes. Once such a virus jumped species and attacked humans, the increased human mobility allowed the virus the opportunity for rapid spread. An infected patient from Guangdong who stayed for one day at a hotel in Hong Kong led to the transmission of the disease to 16 other guests who travelled on to seed outbreaks of the disease in Toronto, Singapore, and Vietnam, as well as within Hong Kong itself. The virus exploited the practices used in modern intensive care of patients with severe respiratory disease and the weakness in infection control practices within our health care systems to cause outbreaks within hospitals, further amplifying the spread of the disease. Health-care itself has become a two-edged sword.
Дополнительное описание: Viral Entry.- Cellular Entry of the SARS Coronavirus: Implications for Transmission, Pathogenicity and Antiviral Strategies.- The Cell Biology of the SARS Coronavirus Receptor, Angiotensin-Converting Enzyme 2.- Structural Molecular Insights into SARS Coro



Animal Coronaviruses

Автор: Leyi Wang
Название: Animal Coronaviruses
ISBN: 1493934120 ISBN-13(EAN): 9781493934126
Издательство: Springer
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Цена: 18167.00 р.
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Описание: It explores conventional immunohistochemistry, virus neutralization, enzyme-linked immunosorbent assays, expression and purification of recombinant viral proteins, and various molecular assays, including conventional and real-time reverse transcription-PCR, reverse genetics methodology, and next generation sequencing and sequence analyses.

Severe acute respiratory syndrome (sars): from benchtop to bedside

Название: Severe acute respiratory syndrome (sars): from benchtop to bedside
ISBN: 9812387536 ISBN-13(EAN): 9789812387530
Издательство: World Scientific Publishing
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Цена: 11880.00 р.
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Описание: This is a comprehensive and up-to-date account of the clinical management of severe acute respiratory syndrome (SARS). It covers the various aspects, from diagnosis, clinical presentation and therapeutic modalities to rehabilitation.

Coronavirus Replication and Reverse Genetics

Автор: Luis Enjuanes
Название: Coronavirus Replication and Reverse Genetics
ISBN: 364205997X ISBN-13(EAN): 9783642059971
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

SARS- and Other Coronaviruses

Автор: Cavanagh
Название: SARS- and Other Coronaviruses
ISBN: 1617378151 ISBN-13(EAN): 9781617378157
Издательство: Springer
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Цена: 19564.00 р.
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Описание: In 2003, the word "coronavirus" spread across the globe, somewhat further than the virus that sparked the panic. In this book, expert researchers examine these devastating viruses through 23 state-of-the-art, widely applicable protocols with minute detail.

Molecular Biology and Pathogenesis of Coronaviruses

Автор: P. J. Rottier
Название: Molecular Biology and Pathogenesis of Coronaviruses
ISBN: 1461593751 ISBN-13(EAN): 9781461593751
Издательство: Springer
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Цена: 6986.00 р.
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Biochemistry and Biology of Coronaviruses

Автор: V. Ter Meulen
Название: Biochemistry and Biology of Coronaviruses
ISBN: 1475704585 ISBN-13(EAN): 9781475704587
Издательство: Springer
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Цена: 13974.00 р.
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Описание: The uniformity and diversity in this virus group was evaluated from a molecular point of view and the replication of coronaviruses appears to involve aspects which may be unique for this virus group.

Coronaviruses

Автор: Helena Jane Maier; Erica Bickerton; Paul Britton
Название: Coronaviruses
ISBN: 1493924370 ISBN-13(EAN): 9781493924370
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This volume aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and practical, Coronaviruses: Methods and Protocols appeals to a wide variety of scientists because it highlights techniques that are currently used in the coronovirology field, while also discussing practices applicable to other virology fields.

Coronaviruses

Автор: M. Lai
Название: Coronaviruses
ISBN: 1468412825 ISBN-13(EAN): 9781468412826
Издательство: Springer
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Цена: 13974.00 р.
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Описание: They contain a large amount of sequence data, including the complete sequence of a 27 Kb coronavirus genome, a novel mechanism of mRNA synthesis that is unique to coronviruses, and many exciting aspects of coronavirus pathogenesis and immunology.

Coronaviruses

Автор: Hubert Laude; Jean-Francois Vautherot
Название: Coronaviruses
ISBN: 1461363055 ISBN-13(EAN): 9781461363057
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented.


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