Knowledge-Based Systems in Biomedicine and Computational Life Science, Tuan D. Pham; Lakhmi C. Jain
Автор: Quarteroni Название: Complex Systems in Biomedicine ISBN: 8847003946 ISBN-13(EAN): 9788847003941 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Поставка под заказ.
Описание: Mathematical modeling of human physiopathology is a tremendously ambitious task. It encompasses the modeling of most diverse compartments such as the cardiovascular, respiratory, skeletal and nervous systems, as well as the mechanical and biochemical interaction between blood flow and arterial walls, or electrocardiac processes and the electric conduction into biological tissues. Mathematical models can be set up to simulate both vasculogenesis (the aggregation and organisation of endothelial cells dispersed in a given environment) and angiogenesis (the formation of new vessels sprouting from an existing vessel) that are relevant to the formation of vascular networks, and in particular to the description of tumor growth. The integration of models aimed at simulating the cooperation and interrelation of different systems is an even more difficult task. It calls for the set up of, for instance, interaction models for the integrated cardio-vascular system and the interplay between central circulation and peripheral compartments, models for the mid-long range cardiovascular adjustments to pathological conditions (e.g. to account for surgical interventions, congenital malformations, or tumor growth), models for the integration among circulation, tissue perfusion, biochemical and thermal regulation, models for parameter identification and sensitivity analysis to parameter changes or data uncertainty – and many others. The heart is a complex system in itself, where electrical phenomena are functionally related with the wall deformation. In its turn, electrical activity is related with heart physiology. It involves nonlinear reaction-diffusion processes and provides the activation stimulus to the heart dynamics and eventually the blood ventricular flow that drives the haemodynamics of the whole circulatory system. In fact, the influence is reciprocal, since the circulatory system in turns affects the heart dynamics and may induce an overload depending upon the individual physiopathologies ( for instance the presence of a stenotic artery or a vascular prosthesis).Virtually, all the fields of mathematics have a role to play in this context. Geometry and approximation theory provide the tools for handling clinical data acquired by tomography or magnetic resonance, identifying meaningful geometrical patterns and producing three-dimensional geometrical models stemming from the original patients data. Mathematical analysis, flow and solid dynamics, stochastic analysis are used to set up the differential models and predict uncertainty. Numerical analysis and high performance computing are needed to numerically solve the complex differential models. Finally, methods from stochastic and statistical analysis are exploited for the modeling and interpretation of space-time patterns. Indeed, the complexity of the problems at hand often stimulates the use of innovative mathematical techniques that are able, for instance, to accurately catch those processes that occur at multiple scales in time and space (like cellular and systemic effects), and that are governed by heterogeneous physical laws.
Описание: This edited volume contains a selection of chapters that are an outgrowth of the - ropean Conference on Mathematical and Theoretical Biology (ECMTB05, Dresden, Germany, July 2005). The peer-reviewed contributions show that mathematical and computational approaches are absolutely essential for solving central problems in the life sciences, ranging from the organizational level of individual cells to the dynamics of whole populations. The contributions indicate that theoretical and mathematical biology is a diverse and interdisciplinary ?eld, ranging from experimental research linked to mathema- cal modeling to the development of more abstract mathematical frameworks in which observations about the real world can be interpreted, and with which new hypotheses for testing can be generated. Today, much attention is also paid to the development of ef?cient algorithms for complex computation and visualisation, notably in molecular biology and genetics. The ?eld of theoretical and mathematical biology and medicine has profound connections to many current problems of great relevance to society. The medical, industrial, and social interests in its development are in fact indisputable.
Автор: Fr?d?ric Cazals; Pierre Kornprobst; Oliver Faugera Название: Modeling in Computational Biology and Biomedicine ISBN: 3642446698 ISBN-13(EAN): 9783642446696 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes synergy between technological advances and input from physics, chemistry, mathematics, statistics and computer science. Surveys progress in bioinformatics, biomedicine and neuroscience, and highlights outstanding theoretical questions.
Автор: Tomasz G. Smolinski; Mariofanna G. Milanova; Aboul Название: Computational Intelligence in Biomedicine and Bioinformatics ISBN: 3642089690 ISBN-13(EAN): 9783642089695 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The purpose of this book is to provide an overview of state-of-the-art methodologies currently utilized for biomedicine and/or bioinformatics-oriented applications. Researchers working in these fields will learn new methods to help tackle their problems.
Автор: Tomasz G. Smolinski; Mariofanna G. Milanova; Aboul Название: Computational Intelligence in Biomedicine and Bioinformatics ISBN: 354070776X ISBN-13(EAN): 9783540707769 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offers an overview of the methodologies that are utilized for biomedicine and/or bioinformatics-oriented applications. This work also includes contributions from researchers applying computational intelligence techniques to important problems in biomedicine and bioinformatics.
Автор: Thomas Deisboeck; J. Yasha Kresh Название: Complex Systems Science in Biomedicine ISBN: 1489978860 ISBN-13(EAN): 9781489978868 Издательство: Springer Рейтинг: Цена: 39182.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh
Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science.
Key Topics Include: - Historic Perspectives of General Systems Thinking - Fundamental Methods and Techniques for Studying Complex Dynamical Systems - Applications from Molecular Networks to Disease Processes - Enabling Technologies for Exploration of Systems in the Life Sciences
Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field.
About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging.
J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.
Автор: Allan L. Goldstein Название: Frontiers in Biomedicine ISBN: 1461368936 ISBN-13(EAN): 9781461368939 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The lectures, approximately one hour in length, were broadcast live from The George Washington University Medical Center in Washington, D. In partnership with Medical Consumer Media, the lectures were simultaneously broadcast live around the world via the Internet with real-time audio streaming and digitized 35mm slide presentation.
Автор: Michael G. Sargent Название: Biomedicine and the Human Condition ISBN: 0521541484 ISBN-13(EAN): 9780521541480 Издательство: Cambridge Academ Рейтинг: Цена: 8394.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: How to avoid disease, how to breed successfully, and how to live to a reasonable age are questions that have long perplexed humankind. This 2005 book explores our progress in understanding these challenges, and the risks and rewards of our attempts to find solutions.
Автор: Ewa Pietka; Jacek Kawa Название: Information Technologies in Biomedicine ISBN: 3642131042 ISBN-13(EAN): 9783642131042 Издательство: Springer Рейтинг: Цена: 46118.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents recent research on Information Technologies in Biomedicine. It includes biomedical signals, medical image processing, computer-aided diagnosis and surgery, biometrics, healthcare and telemedicine, biomechanics, biomaterials, bioinformatics.
Автор: Prainsack Название: Solidarity in Biomedicine and Beyond ISBN: 110707424X ISBN-13(EAN): 9781107074248 Издательство: Cambridge Academ Рейтинг: Цена: 17266.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In times of global economic and political crises, the notion of solidarity is gaining new currency. Exemplified by three case studies from medicine and health, this book shows how solidarity can make a difference in how we frame problems in biomedicine, and help develop innovative solutions.
Автор: Ewa Pi?tka; Jacek Kawa; Wojciech Wieclawek Название: Information Technologies in Biomedicine, Volume 3 ISBN: 3319065920 ISBN-13(EAN): 9783319065922 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Image Analysis and Applications.- Bioinformatics.
Автор: Ewa Pi?tka; Jacek Kawa; Wojciech Wieclawek Название: Information Technologies in Biomedicine, Volume 4 ISBN: 3319065955 ISBN-13(EAN): 9783319065953 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Home care, remote rehabilitation assistance, safety of the elderly requires new areas to be explored in telemedicine and telegeriatrics.This book is a great reference tool for scientists who deal with problems of designing and implementing processing tools employed in systems that assist clinicians in patient diagnosis and treatment.
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