Complex Systems Science in Biomedicine, Thomas Deisboeck; J. Yasha Kresh
Автор: Quarteroni Название: Complex Systems in Biomedicine ISBN: 8847003946 ISBN-13(EAN): 9788847003941 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Поставка под заказ.
Описание: Mathematical modeling of human physiopathology is a tremendously ambitious task. It encompasses the modeling of most diverse compartments such as the cardiovascular, respiratory, skeletal and nervous systems, as well as the mechanical and biochemical interaction between blood flow and arterial walls, or electrocardiac processes and the electric conduction into biological tissues. Mathematical models can be set up to simulate both vasculogenesis (the aggregation and organisation of endothelial cells dispersed in a given environment) and angiogenesis (the formation of new vessels sprouting from an existing vessel) that are relevant to the formation of vascular networks, and in particular to the description of tumor growth. The integration of models aimed at simulating the cooperation and interrelation of different systems is an even more difficult task. It calls for the set up of, for instance, interaction models for the integrated cardio-vascular system and the interplay between central circulation and peripheral compartments, models for the mid-long range cardiovascular adjustments to pathological conditions (e.g. to account for surgical interventions, congenital malformations, or tumor growth), models for the integration among circulation, tissue perfusion, biochemical and thermal regulation, models for parameter identification and sensitivity analysis to parameter changes or data uncertainty – and many others. The heart is a complex system in itself, where electrical phenomena are functionally related with the wall deformation. In its turn, electrical activity is related with heart physiology. It involves nonlinear reaction-diffusion processes and provides the activation stimulus to the heart dynamics and eventually the blood ventricular flow that drives the haemodynamics of the whole circulatory system. In fact, the influence is reciprocal, since the circulatory system in turns affects the heart dynamics and may induce an overload depending upon the individual physiopathologies ( for instance the presence of a stenotic artery or a vascular prosthesis).Virtually, all the fields of mathematics have a role to play in this context. Geometry and approximation theory provide the tools for handling clinical data acquired by tomography or magnetic resonance, identifying meaningful geometrical patterns and producing three-dimensional geometrical models stemming from the original patients data. Mathematical analysis, flow and solid dynamics, stochastic analysis are used to set up the differential models and predict uncertainty. Numerical analysis and high performance computing are needed to numerically solve the complex differential models. Finally, methods from stochastic and statistical analysis are exploited for the modeling and interpretation of space-time patterns. Indeed, the complexity of the problems at hand often stimulates the use of innovative mathematical techniques that are able, for instance, to accurately catch those processes that occur at multiple scales in time and space (like cellular and systemic effects), and that are governed by heterogeneous physical laws.
Автор: Lackie John Название: A Dictionary of Biomedicine ISBN: 0199549354 ISBN-13(EAN): 9780199549351 Издательство: Oxford Academ Рейтинг: Цена: 2770.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This dictionary includes 10,000 A-Z entries on all areas of biomedicine. It also covers terms from related areas, including anatomy, genetics, pathology, pharmacology, and clinical medicine. Fully cross-referenced and with web links, this is a clear and authoritative guide to an increasingly important area of medicine.
Описание: This book presents a sample of research on knowledge-based systems in biomedicine and computational life science. The contributions include: personalized stress diagnosis system, image analysis system for breast cancer diagnosis, analysis of neuronal cell images, structure prediction of protein, relationship between two mental disorders, detection of cardiac abnormalities, holistic medicine based treatment and analysis of life-science data.
Описание: This edited volume contains a selection of chapters that are an outgrowth of the - ropean Conference on Mathematical and Theoretical Biology (ECMTB05, Dresden, Germany, July 2005). The peer-reviewed contributions show that mathematical and computational approaches are absolutely essential for solving central problems in the life sciences, ranging from the organizational level of individual cells to the dynamics of whole populations. The contributions indicate that theoretical and mathematical biology is a diverse and interdisciplinary ?eld, ranging from experimental research linked to mathema- cal modeling to the development of more abstract mathematical frameworks in which observations about the real world can be interpreted, and with which new hypotheses for testing can be generated. Today, much attention is also paid to the development of ef?cient algorithms for complex computation and visualisation, notably in molecular biology and genetics. The ?eld of theoretical and mathematical biology and medicine has profound connections to many current problems of great relevance to society. The medical, industrial, and social interests in its development are in fact indisputable.
Автор: Janine E. Janosky; Shelley L. Leininger; Michael P Название: Single Subject Designs in Biomedicine ISBN: 9400791070 ISBN-13(EAN): 9789400791077 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Single Subject Designs in Biomedicine draws upon the rich history of single case research within the educational and behavioral research settings and extends the application to the field of biomedicine. Biomedical illustrations are used to demonstrate the processes of designing, implementing, and evaluating a single subject design. Strengths and limitations of various methodologies are presented, along with specific clinical areas of application in which these applications would be appropriate. Statistical and visual techniques for data analysis are also discussed. The breadth and depth of information provided is suitable for medical students in research oriented courses, primary care practitioners and medical specialists seeking to apply methods of evidence practice to improve patient care, and medical researchers who are expanding their methodological expertise to include single subject designs. Increasing awareness of the utility in the single subject design could enhance treatment approach and evaluation both in biomedical research and medical care settings.
Автор: Fr?d?ric Cazals; Pierre Kornprobst; Oliver Faugera Название: Modeling in Computational Biology and Biomedicine ISBN: 3642446698 ISBN-13(EAN): 9783642446696 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes synergy between technological advances and input from physics, chemistry, mathematics, statistics and computer science. Surveys progress in bioinformatics, biomedicine and neuroscience, and highlights outstanding theoretical questions.
Автор: Thomas Jue; Kazumi Masuda Название: Application of Near Infrared Spectroscopy in Biomedicine ISBN: 1489979441 ISBN-13(EAN): 9781489979445 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume balances the need for physical science/mathematics formalism with a demand for biomedical perspectives. It details current instrumentation and techniques as well as illustrates current applications in addressing complex biology questions.
Автор: Dietmar P.F. M?ller Название: Advanced Simulation in Biomedicine ISBN: 038797184X ISBN-13(EAN): 9780387971841 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents a collection of invited contributions, each reflecting an area of biomedicine in which simulation techniques have been successfully applied. It is the objective of this book to present advanced simulation techniques in biomedicine and outline current research, as well as to point out open problems, in this dynamic field.
Автор: Zhen Chen; Aiyi Liu; Yongming Qu; Larry Tang; Nait Название: Applied Statistics in Biomedicine and Clinical Trials Design ISBN: 3319362887 ISBN-13(EAN): 9783319362885 Издательство: Springer Рейтинг: Цена: 26552.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The peer-reviewed contributions were solicited and selected from some 400 presentations at the annual meeting of the International Chinese Statistical Association (ICSA), held with the International Society for Biopharmaceutical Statistics (ISBS).
Автор: Allan L. Goldstein Название: Frontiers in Biomedicine ISBN: 1461368936 ISBN-13(EAN): 9781461368939 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The lectures, approximately one hour in length, were broadcast live from The George Washington University Medical Center in Washington, D. In partnership with Medical Consumer Media, the lectures were simultaneously broadcast live around the world via the Internet with real-time audio streaming and digitized 35mm slide presentation.
Автор: Zhen Chen; Aiyi Liu; Yongming Qu; Larry Tang; Nait Название: Applied Statistics in Biomedicine and Clinical Trials Design ISBN: 3319126938 ISBN-13(EAN): 9783319126937 Издательство: Springer Рейтинг: Цена: 26552.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The peer-reviewed contributions were solicited and selected from some 400 presentations at the annual meeting of the International Chinese Statistical Association (ICSA), held with the International Society for Biopharmaceutical Statistics (ISBS).
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