Synthetic mRNA, Robert E. Rhoads

Автор: Fabrice Lejeune
Название: Nonsense-Mediated mRNA Decay in Human Disease
ISBN: 0128044683 ISBN-13(EAN): 9780128044681
Издательство: Elsevier Science
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Цена: 11620.00 р.
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Описание: . Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD). . It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine.

Автор: Thomas K?hler; Dirk La?ner; Anne-Katrin Rost; Barb
Название: Quantitation of mRNA by Polymerase Chain Reaction
ISBN: 3642797148 ISBN-13(EAN): 9783642797149
Издательство: Springer
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Цена: 16979.00 р.
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Описание: In this laboratory "cook-book", the authors provide a concise guide to PCR-based techniques to quantify nucleic acids in biological and clinical samples using exclusively nonradioactive detection methods, e.g.

Автор: Shree Nath Singh
Название: Microbial Degradation of Synthetic Dyes in Wastewaters
ISBN: 3319385283 ISBN-13(EAN): 9783319385280
Издательство: Springer
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Цена: 16977.00 р.
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Описание: Today synthetic dyes are used extensively in the textile dyeing, paper printing, color photography, pharmaceuticals, food and drink, cosmetic and leather industries.

Автор: Klemens J. Hertel
Название: Spliceosomal Pre-mRNA Splicing
ISBN: 149396044X ISBN-13(EAN): 9781493960446
Издательство: Springer
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Цена: 16769.00 р.
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Описание:

Part I: Introductory Chapters

1. The Pre-mRNA Splicing Reaction

Somsakul Wongpalee and Shalini Sharma

2. Diversity and Evolution of Spliceosomal Systems

Scott William Roy and Manuel Irimia

3. Mechanisms of Spliceosomal Assembly

Ni-ting Chiou and Kristen W. Lynch

4. Alternative Pre-mRNA Splicing

Stacey D. Wagner and J. Andrew Berglund

5. Regulation of Alternative Pre-mRNA Splicing

Miguel B. Coelho and Christopher W.J. Smith

6. Introduction to Co-Transcriptional RNA Splicing

Evan C. Merkhofer, Peter Hu, and Tracy L. Johnson

7. Chromatin and Splicing

Nazmul Haque and Shalini Oberdoerffer

Part II: Methods Chapters

8. Preparation of Splicing Competent Nuclear Extracts

Chiu-Ho T. Webb and Klemens J. Hertel

9. Preparation of Yeast Whole Cell Splicing Extract

Elizabeth A. Dunn and Stephen D. Rader

10. Efficient Splinted Ligation of Synthetic RNA Using RNA Ligase

Martha R. Stark and Stephen D. Rader

11. In Vitro Assay of Pre-mRNA Splicing in Mammalian Nuclear Extract

Maliheh Movassat, William F. Mueller, and Klemens J. Hertel

12. Kinetic Analysis of In Vitro Pre-mRNA Splicing in HeLa Nuclear Extract

William F. Mueller and Klemens J. Hertel

13. In Vitro Systems for Coupling RNAP II Transcription to Splicing and Polyadenylation

Eric G. Folco and Robin Reed

14. Isolation and Accumulation of Spliceosomal Assembly Intermediates

Janine O. Ilagan and Melissa S. Jurica

15. Complementation of U4 snRNA in S. cerevisiae Splicing Extracts for Biochemical Studies of snRNP Assembly and Function

Martha R. Stark and Stephen D. Rader

16. Expression and Purification of Splicing Proteins from Mammalian Cells

Eric Allemand and Michelle L. Hastings

17. Single Molecule Approaches for Studying Spliceosome Assembly and Catalysis

Eric G. Anderson and Aaron A. Hoskins

18. Cell-Based Splicing of Minigenes

Sarah A. Smith and Kristen W. Lynch

19. Quantifying the Ratio of Spliceosome Components Assembled on Pre-mRNA

Noa Neufeld, Yehuda Brody, and Yaron Shav-Tal

20. Antisense Methods to Modulate Pre-mRNA Splicing

Joonbae Seo, Eric W. Ottesen, and Ravindra N. Singh

21. Using Yeast Genetics to Study Splicing Mechanisms

Munshi Azad Hossain and Tracy L. Johnson

22. Medium Throughput Analysis of Alternative Splicing by Fluorescently Labeled RT-PCR

Ryan Percifield, Daniel Murphy, and Peter Stoilov

23. Chromatin Immunoprecipitation Approaches to Determine Co-Transcriptional Nature of Splicing

Nicole I. Bieberstein, Korinna Straube, and Karla M. Neugebauer

24. Computational Approaches to Mine Publicly Available Databases

Rodger B. Voelker, William A. Cresko, and J. Andrew Berglund

25. Approaches to Link RNA Secondary Structures with Splicing Regulation

Mireya Plass and Eduardo Eyras

26. Methods to Study Splicing from High-Throughput RNA Sequencing Data

Gael P. Alamancos, Eneritz Agirre, and Eduardo Eyras

27. Global Protein-RNA Interaction Mapping at Single Nucleotide Resolution by iCLIP-Seq

Chengguo Yao, Lingjie Weng, and Yongsheng Shi

28. Predicting Alternative Splicing

Yoseph Barash and Jorge Vaquero Garcia

Автор: Shi, Yongsheng.
Название: MRNA processing :
ISBN: 1493972030 ISBN-13(EAN): 9781493972036
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This detailed volume assembles a number of the most commonly used and state-of-the-art methodologies in the revolutionary field of mRNA processing in order to aid researchers in choosing the best method for their specific problems.

Автор: Wilfried Weber; Martin Fussenegger
Название: Synthetic Gene Networks
ISBN: 1493962248 ISBN-13(EAN): 9781493962242
Издательство: Springer
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Цена: 20263.00 р.
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Описание: This book shows how to design and build synthetic gene networks in different host backgrounds. Coverage includes concepts for devising synthetic gene networks and application of mathematical models to the predictable engineering of desired network features.

Автор: Michael Krogh Jensen; Jay D Keasling
Название: Synthetic Metabolic Pathways
ISBN: 1493972944 ISBN-13(EAN): 9781493972944
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This volume outlines key steps associated with the design, building, and testing of synthetic metabolic pathways for optimal cell factory performance and robustness, and illustrates how data-driven learning from these steps can be used for rational cost-effective engineering of cell factories with improved performance.

Автор: Klaus Naumann
Название: Synthetic Pyrethroid Insecticides: Chemistry and Patents
ISBN: 3642748546 ISBN-13(EAN): 9783642748547
Издательство: Springer
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Цена: 18167.00 р.
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Автор: Singh
Название: Systems Biology Application in Synthetic Biology
ISBN: 8132228073 ISBN-13(EAN): 9788132228073
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This book introduces students to methods that will help them understand behaviour in terms of cellular components and their interactions in non-intuitive ways, which calls for an interdisciplinary approach combining mathematical, chemical, computational and biological strategies. Tibor Ganti was one of the early pioneers who proposed a theoretical framework to understand living principles in terms of chemical transformation cycles and their coupling. The twenty-first century then brought with it a novel ‘systems’ paradigm, which shone new light on all previous work and was accompanied by numerous implications for the way we conceive of chemical and biological complexity today. This book seeks to equip students to take advantage of any field that investigates living systems. Based on a conceptualisation of science-oriented branches, engineering-oriented branches and biology as astoundingly complex fields, those structures laden with biochemical detail encompass a deeper theory unifying our knowledge of designed systems. Readers will be pleasantly surprised at how lucidly the topics are presented. The book offers an indispensable resource for students and professionals working in systems and synthetic biology or any of the various related fields of research.

Автор: Alexey Melkikh; Maria Sutormina
Название: Developing Synthetic Transport Systems
ISBN: 9400758928 ISBN-13(EAN): 9789400758926
Издательство: Springer
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Цена: 10448.00 р.
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Описание: Understanding the general laws of an effective system for transport of substances in cells is an important goal of systems and synthetic biology, this book helps us to answer why transport subsystem of a cell is arranged as it is. It describes linear and nonlinear programming, game theory for models of ion transport in different types of cells.

Автор: Atala
Название: Synthetic Biodegradable Polymer Scafolds
ISBN: 0817639195 ISBN-13(EAN): 9780817639198
Издательство: Springer
Цена: 26120.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Brings together articles from leading researchers in the field of the synthesis and properties of biodegradable polymers utilized in tissue engineering. It should provide guidance on potential new materials or applications in the tissue engineering field.

Автор: Klemens J. Hertel
Название: Spliceosomal Pre-mRNA Splicing
ISBN: 1627039791 ISBN-13(EAN): 9781627039796
Издательство: Springer
Рейтинг:
Цена: 16769.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Part I: Introductory Chapters

1. The Pre-mRNA Splicing Reaction

Somsakul Wongpalee and Shalini Sharma

2. Diversity and Evolution of Spliceosomal Systems

Scott William Roy and Manuel Irimia

3. Mechanisms of Spliceosomal Assembly

Ni-ting Chiou and Kristen W. Lynch

4. Alternative Pre-mRNA Splicing

Stacey D. Wagner and J. Andrew Berglund

5. Regulation of Alternative Pre-mRNA Splicing

Miguel B. Coelho and Christopher W.J. Smith

6. Introduction to Co-Transcriptional RNA Splicing

Evan C. Merkhofer, Peter Hu, and Tracy L. Johnson

7. Chromatin and Splicing

Nazmul Haque and Shalini Oberdoerffer

Part II: Methods Chapters

8. Preparation of Splicing Competent Nuclear Extracts

Chiu-Ho T. Webb and Klemens J. Hertel

9. Preparation of Yeast Whole Cell Splicing Extract

Elizabeth A. Dunn and Stephen D. Rader

10. Efficient Splinted Ligation of Synthetic RNA Using RNA Ligase

Martha R. Stark and Stephen D. Rader

11. In Vitro Assay of Pre-mRNA Splicing in Mammalian Nuclear Extract

Maliheh Movassat, William F. Mueller, and Klemens J. Hertel

12. Kinetic Analysis of In Vitro Pre-mRNA Splicing in HeLa Nuclear Extract

William F. Mueller and Klemens J. Hertel

13. In Vitro Systems for Coupling RNAP II Transcription to Splicing and Polyadenylation

Eric G. Folco and Robin Reed

14. Isolation and Accumulation of Spliceosomal Assembly Intermediates

Janine O. Ilagan and Melissa S. Jurica

15. Complementation of U4 snRNA in S. cerevisiae Splicing Extracts for Biochemical Studies of snRNP Assembly and Function

Martha R. Stark and Stephen D. Rader

16. Expression and Purification of Splicing Proteins from Mammalian Cells

Eric Allemand and Michelle L. Hastings

17. Single Molecule Approaches for Studying Spliceosome Assembly and Catalysis

Eric G. Anderson and Aaron A. Hoskins

18. Cell-Based Splicing of Minigenes

Sarah A. Smith and Kristen W. Lynch

19. Quantifying the Ratio of Spliceosome Components Assembled on Pre-mRNA

Noa Neufeld, Yehuda Brody, and Yaron Shav-Tal

20. Antisense Methods to Modulate Pre-mRNA Splicing

Joonbae Seo, Eric W. Ottesen, and Ravindra N. Singh

21. Using Yeast Genetics to Study Splicing Mechanisms

Munshi Azad Hossain and Tracy L. Johnson

22. Medium Throughput Analysis of Alternative Splicing by Fluorescently Labeled RT-PCR

Ryan Percifield, Daniel Murphy, and Peter Stoilov

23. Chromatin Immunoprecipitation Approaches to Determine Co-Transcriptional Nature of Splicing

Nicole I. Bieberstein, Korinna Straube, and Karla M. Neugebauer

24. Computational Approaches to Mine Publicly Available Databases

Rodger B. Voelker, William A. Cresko, and J. Andrew Berglund

25. Approaches to Link RNA Secondary Structures with Splicing Regulation

Mireya Plass and Eduardo Eyras

26. Methods to Study Splicing from High-Throughput RNA Sequencing Data

Gael P. Alamancos, Eneritz Agirre, and Eduardo Eyras

27. Global Protein-RNA Interaction Mapping at Single Nucleotide Resolution by iCLIP-Seq

Chengguo Yao, Lingjie Weng, and Yongsheng Shi

28. Predicting Alternative Splicing

Yoseph Barash and Jorge Vaquero Garcia