Systems Biology of Metabolic and Signaling Networks, Miguel A. Aon; Valdur Saks; Uwe Schlattner
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Aik-Choon Tan; Paul H. Huang Название: Kinase Signaling Networks ISBN: 1493971522 ISBN-13(EAN): 9781493971527 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Beginning with a section on synthetic biology, chemical biology, and screening approaches to kinase signaling networks, the book continues with sections on mass spectrometry and metabolic analysis of kinase signaling as well as computational analysis of kinase signaling networks.
Автор: Xuedong Liu; Meredith D. Betterton Название: Computational Modeling of Signaling Networks ISBN: 1493958437 ISBN-13(EAN): 9781493958436 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focusing on Systems of ODEs, parameterization of signaling models, signaling pathways, mass-action kinetics and ODEs and how to use modeling to plan experiments, this Methods in Molecular Biology (TM) book details steps for getting optimal laboratory results.
Автор: Kauffman Alexander S Название: Kisspeptin Signaling in Reproductive Biology ISBN: 1461461987 ISBN-13(EAN): 9781461461982 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on kisspeptin and its role in reproductive biology. It looks at interactions between Kisspeptin and Neurokinin B and reviews model systems for studying kisspeptin signaling.
Автор: Miguel A. Aon; Valdur Saks; Uwe Schlattner Название: Systems Biology of Metabolic and Signaling Networks ISBN: 3642385044 ISBN-13(EAN): 9783642385049 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Starting with historical roots, this work explores the systems biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.
Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A," the new volume in the "Methods in Enzymology" series, " "continues the legacy of this premier serial with quality chapters authored by leaders in the field.
This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Contains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbesPresents sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways
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