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Gene Vaccines, Josef Thalhamer; Richard Weiss; Sandra Scheiblhofe


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Автор: Josef Thalhamer; Richard Weiss; Sandra Scheiblhofe
Название:  Gene Vaccines
ISBN: 9783709119297
Издательство: Springer
Классификация:

ISBN-10: 3709119294
Обложка/Формат: Paperback
Страницы: 330
Вес: 0.48 кг.
Дата издания: 23.08.2016
Язык: English
Издание: Softcover reprint of
Иллюстрации: Xi, 330 p.; xi, 330 p.
Размер: 234 x 156 x 18
Читательская аудитория: General (us: trade)
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.
Дополнительное описание: Preface.- 1 General mechanisms of gene vaccines.- 2 Strategies to Improve DNA Vaccine Potency: HPV-associated Cervical Cancer as a Model System.- 3 Immune-activating mechanisms of replicase-based DNA and RNA vaccines and their role in immune-apoptosis.- 4



Vaccines and Autoimmunity

Автор: Yehuda Shoenfeld,Nancy Agmon–Levin
Название: Vaccines and Autoimmunity
ISBN: 1118663438 ISBN-13(EAN): 9781118663431
Издательство: Wiley
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Цена: 22485.00 р.
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Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.

New Trends and Developments in Vaccines

Автор: A. Voller; C.M. Abraham
Название: New Trends and Developments in Vaccines
ISBN: 9401166323 ISBN-13(EAN): 9789401166324
Издательство: Springer
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Цена: 6986.00 р.
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Описание: It was not too long ago that many physicians and biomedical scientists felt that the era of `vaccines` for protecting mankind against infectious disease was coming to an end.

Vaccines

Автор: Gregory Gregoriadis; Brenda McCormack; Anthony C.
Название: Vaccines
ISBN: 0306452839 ISBN-13(EAN): 9780306452833
Издательство: Springer
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Цена: 15672.00 р.
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Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1994.

DNA Vaccines

Автор: Monica Rinaldi; Daniela Fioretti; Sandra Iurescia
Название: DNA Vaccines
ISBN: 1493946536 ISBN-13(EAN): 9781493946532
Издательство: Springer
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Цена: 16769.00 р.
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Описание: DNA Vaccines: Methods and Protocols, Third Edition explores innovative approaches and technologies used to design, deliver, and enhance the efficacy of DNA vaccines.

Molecular Vaccines

Автор: Giese Matthias
Название: Molecular Vaccines
ISBN: 331900977X ISBN-13(EAN): 9783319009773
Издательство: Springer
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Цена: 26122.00 р.
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Описание: This book examines all aspects of global molecular vaccine research and development. It describes the development of new vaccines from bench to preclinical to clinical studies and launch to the market under EMA and FDA guidelines.

Genomics,Proteomics & Vaccines.2004

Автор: Grandi
Название: Genomics,Proteomics & Vaccines.2004
ISBN: 0470856165 ISBN-13(EAN): 9780470856161
Издательство: Wiley
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Цена: 29296.00 р.
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Описание: The complete genome sequences of many bacteria are available, and comparisons of pathogenic strains with non pathogenic relatives are becoming more common. This will enable researchers to target vaccine development towards specific gene products that traditional approaches of vaccine research failed to discover.

DNA Vaccines

Автор: Monica Rinaldi; Daniela Fioretti; Sandra Iurescia
Название: DNA Vaccines
ISBN: 1493904094 ISBN-13(EAN): 9781493904099
Издательство: Springer
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Цена: 23757.00 р.
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Описание: DNA Vaccines: Methods and Protocols, Third Edition explores innovative approaches and technologies used to design, deliver, and enhance the efficacy of DNA vaccines.

Vaccines: Are they Worth a Shot?

Автор: Andrea Grignolio; Joan Rundo
Название: Vaccines: Are they Worth a Shot?
ISBN: 3319681052 ISBN-13(EAN): 9783319681054
Издательство: Springer
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Цена: 4191.00 р.
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Описание: 1. The parents of unvaccinated children

1.1. The 80s, the beginning of the crisis (or resistance)

1.2. Education about risk

1.3. Social changes: The doctor-patient relationship in jeopardy

1.4. Unexpected impact of late fecundity

2. A brief history of the anti-vaccination movements

2.1. The anti-vaccination movements between 1700 and 1800: Roots of obligation and objection

2.2. The anti-vaccination movements in 1900: Media and politics

3. Web alarms: autism, mercury and immune overload

3.1. Conspiracy on the Internet: separating fact from fiction

3.2. Economic criticism: Big Pharma and the allure of patents

3.3. Logic errors: the precautionary principle and the equal balance mistake

3.4. False or manipulated data: Autism

3.5. Prejudices and ideologies: Purported overload and weakening of the immune system

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4. The antivax "experts" five ways to recognize them

4.1. Alternative philosophies: homeopathy, anthroposophy and Waldarf -Steiner schools

4.2. The "alternative therapies" Five clues that reveal a charlatan

5. Past, present, and future of vaccines

5.1. Evolutionary history of naturally acquired immunity

5.2. Artificially acquired immunity: success and safety of vaccines

5.3. Therapeutic vaccines of the future: cancer and neurodegenerative diseases

6. Conclusions

6.1. A new alliance between scientists and citizens for a "knowledge society"

6.2. Some tools for good communication strategies to combat anti-vaccination resistance
RNA Vaccines

Автор: Kramps
Название: RNA Vaccines
ISBN: 1493964798 ISBN-13(EAN): 9781493964796
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume provides an overview of the field and practical hints for vaccinologists in academia and industry. Chapters provide protocols on self-replicating RNA vectors, non-replication mRNA vectors, adjuvantation and delivery, and preclinical and clinical development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA Vaccines: Methods and Protocols aims to increased collaboration on RNA vaccines between basic and applied scientists in academia, government, and industry to develop future solutions for today’s challenges.

Cancer Vaccines

Автор: Lawman
Название: Cancer Vaccines
ISBN: 1493903446 ISBN-13(EAN): 9781493903443
Издательство: Springer
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Цена: 30745.00 р.
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Development of Novel Vaccines

Автор: Alexander von Gabain; Christoph Klade
Название: Development of Novel Vaccines
ISBN: 3709117046 ISBN-13(EAN): 9783709117040
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Covering the entire process of developing a vaccine-from early, basic research right up to the final product itself, and approaching the subject from a variety of perspectives, this volume will be required reading for researchers engaged in vaccine creation.

Veterinary Vaccines

Автор: R. Pandey; S. H?glund; G. Prasad
Название: Veterinary Vaccines
ISBN: 1461392284 ISBN-13(EAN): 9781461392286
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out.


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