T Helper Cell Differentiation and Their Function, Bing Sun
Автор: Bing Sun Название: T Helper Cell Differentiation and Their Function ISBN: 9401794863 ISBN-13(EAN): 9789401794862 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book will focus on the differentiation and regulation of subsets of CD4+ T cells. It will also cover other aspects of research on these cells, which has made great advances in recent years, such as subsets’ plasticity and their role in healthy and disease conditions. The book provides researchers and graduate students with a cutting-edge and comprehensive overview of essential research on CD4+ T cells.
Автор: L. Nover; W. Berg; G. Butschak; M. Luckner; B. Par Название: Cell Differentiation ISBN: 3642680224 ISBN-13(EAN): 9783642680229 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cell differentiation comprises five main aspects: (1) signal reception and transformation, (2) selective rearrangements of the genetic material, (3) differen- tial gene expression, (4) organization of gene expression programs and (5) intercellular coordination of cell differentiation within the developmental programs of multicellular organisms.
Автор: Lugli Название: T-Cell Differentiation ISBN: 1493965468 ISBN-13(EAN): 9781493965465 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides protocols to successfully apply cutting-edge technologies to characterize the biology of T cells at an unprecedented level of complexity. Chapters guide readers through flow cytometry and fluorescence-activated cell sorting, the behaviour of single T cells after adoptive cell transfer (ACT), single cell gene expression by multiplex PCR, lentiviral transduction approaches, protocols to derive large numbers of early-differentiated memory T cells by using dedicated cytokines cocktails, approaches to measure telomerase activity in terminally differentiated T cells, and approaches to define Treg cells at the phenotypic and functional level. The final part of the book is dedicated to the analysis of the differentiation and effector functions of innate T cells, namely the well-known ?/? T cells, and the recently identified CD8+ mucosal associated invariant T (MAIT) cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T-Cell Differentiation: Methods and Protocols aims to provide protocols that are fundamental to monitor the T cell compartment at the level of single cells in pathological and immunotherapy conditions.
Описание: Apoptosis is currently one of the fastest moving fields in biology with spectacular progress made over the past few years in delineating the molecular It is now indisputable that apoptosis mechanisms which underlie this process.
Описание: Present trends in biological research show that it is necessary to know the structures thoroughly, from the ultrastructural cytological scale to the scale of tissue and organ arrangement, even for physiological research on either cells, tissues, or whole organs.
Автор: Jean-Pierre Tassan; Jacek Z. Kubiak Название: Asymmetric Cell Division in Development, Differentiation and Cancer ISBN: 3319531492 ISBN-13(EAN): 9783319531496 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer.To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth.
Автор: J. M. Ashworth Название: Cell Differentiation ISBN: 0412117606 ISBN-13(EAN): 9780412117602 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The restrictions on base pairing- A pairing with T (U), and G pairing with C - in nature assures the fidelity of replication of DNA in cell division, and of transcription.
Описание: This series was established to create comprehensive treatises on specific topics in developmental biology. The specialist in any aspect of developmental biology should understand the experimental back- ground of the specialty and be able to place that body of information in context, in order to ascertain where additional research would be fruitful.
Описание: This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
Автор: J. Reinert; H. Holtzer Название: Cell Cycle and Cell Differentiation ISBN: 3662216930 ISBN-13(EAN): 9783662216934 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: One of the ways in which this situation might be improved would be to find a broader experimental basis, including a better understanding of the relationship between the cell cycle and cell differentiation.
Автор: W. J. Gehring Название: Genetic Mosaics and Cell Differentiation ISBN: 3662219522 ISBN-13(EAN): 9783662219522 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
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