Lipid-mediated Protein Signaling, Daniel G.S. Capelluto
Автор: Daniel G.S. Capelluto Название: Lipid-mediated Protein Signaling ISBN: 9400763301 ISBN-13(EAN): 9789400763302 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Автор: Amita Pandey; Girdhar K. Pandey Название: The UNC-53-mediated Interactome ISBN: 3319078267 ISBN-13(EAN): 9783319078267 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles.
Автор: Devendra K. Choudhary; Ajit Varma Название: Microbial-mediated Induced Systemic Resistance in Plants ISBN: 9811003874 ISBN-13(EAN): 9789811003875 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. Changes in phytochemicals in response to rhizospheric microorganisms infection Mehrnaz Hatami, Mansour Ghorbanpour 2. Bacillus-mediated induced systemic resistance (ISR) against Fusarium corm rot Shanu Magotra, Deepika Trakroo, Sneha Ganjoo and Jyoti Vakhlu 3. Plant growth-promoting rhizobacteria: key mechanisms of action Mбrcia do Vale Barreto Figueiredo, Aurenнvia Bonifacio, Artenisa Cerqueira Rodrigues, Fabio Fernando de Araujo 4. Priming of plant defense and plant growth in disease challenged crops using microbial consortia Murugan Kumar, Nanjappan Karthikeyan, and Radha Prasanna 5. Seed priming mediated induced disease resistance in arid zone plants Rakesh Pathak, Praveen Gehlot and S.K. Singh 6. Trichoderma secondary metabolites: their biochemistry and possible role in disease management Anita Surendra Patil, Surendra Rajaram Patil and Hariprasad Madhukarrao Paikrao 7. Induced systemic resistance in rice Kalaivani K. Nadarajah 8. Plant growth promoting rhizobacteria mediated acquired systemic resistance in plants against pests and diseases S.K. Singh, Rakesh Pathak and Vipin Chaudhary 9. Acyl homoserine lactone producing rhizobacteria-elicit systemic resistance in plants Ganga Viswanath, Jegan Sekar, and V.R. Prabhavathy 10. Biological Control of chickpea Fusarium wilt using rhizobacteria "PGPR" Souad Zaim, Lakhdar Belabid, Bassam Bayaa 11. AM fungal effect on the growth of selective dicot and monocot plants B. Sadhana*, P. K. Monica and S. Siva Sankari 12. Trichoderma spp.: Efficient Inducers of Systemic Resistance in Plants Kartikay Bisen, Chetan Keswani, J. S. Patel, B. K. Sarma, H. B. Singh 13. Induced systemic resistance by rhizospehric microbes Manoj Kumar, Priyanku Teotia, Ajit Varma, Narendra Tuteja, and Vivek Kumar 14. Combinations of plant growth-promoting rhizobacteria (PGPR) for initiation of systemic resistance against tree diseases Vivek Kumar, Ajit Varma Narendra Tuteja and Manoj Kumar 15. Plant growth promoting microbial-mediated induced systemic resistance in plants: induction, mechanism and expression Shekhar Jain, Ajit Varma, Narendra Tuteja, D.K. Choudhary
Автор: Jean-Francois Jeannin Название: Lipid A in Cancer Therapy ISBN: 1441916024 ISBN-13(EAN): 9781441916020 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The work needed to develop lipid A as an effective anti-cancer agent lies ahead in the near future. This volume is a timely contribution and provides a much needed up-to-date overview of the chemical, biological and physiological aspects of lipid A.
Автор: Gianvito Martino; Luciano Adorini Название: From Basic Immunology to Immune-Mediated Demyelination ISBN: 8847000548 ISBN-13(EAN): 9788847000544 Издательство: Springer Рейтинг: Цена: 32651.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Morphological, physiological and pathological evidence demonstrates that ner- vous and immune systems interact not only in maintaining brain homeostasis, but also in causing neurological diseases. The studyofthese interactions repre- sents the basis on which neuroimmunologyhas grown during the years. At pre- sent, several neurological diseases are recognized to be caused by a derange- ment of the immune system in either its regulatory or effector functions. The main scope ofthis book, to discuss how an unbalanced immune system maylead to immune-mediated neurological diseases, is achieved in three parts. The first part provides an overview on how the immune system works. This is propaedeutical to understanding interactions between the immune and ner- vous systems, which are discussed in the second part. The third part of the book focuses on one particular area of neuroimmunology, the immune disor- ders leading to the damage of central and peripheral myelin. Given the opportunity to review first the immune system in itself and then how it operates during immune-mediated demyelinating disorders, we have tried to provide the reader with a basis for clearly understanding how interac- tions between the immune and nervous systems can be protective or pathoge- nic. This knowledge is a prerequisite for a rationale immune intervention tar- geting these disorders.
Автор: Swathi Arur Название: Signaling-Mediated Control of Cell Division ISBN: 3319448196 ISBN-13(EAN): 9783319448190 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. Role of chromatin modifications in germline stem cell differentiationPooja Flora, Maitreyi Upadhyay, Alicia McCarthy, Prashanth Rangan Prashanth Rangan prangan@albany.edu 2. Regulation of the balance between proliferation and differentiation in germline stem cells.Ramya Singh and David HansenDavid Donald Hansen dhansen@ucalgary.ca 3. Control of germ line stem cell lineages by diet and physiologyKaitlyn Laws and Daniela Drummond-BarbosaDaniela Barbosa dbarbosa@jhu.edu 4. Signal-mediated regulation of meiotic prophase I during oogenesisKenneth Trimmer and Swathi ArurSwathi Arur sarur@mdanderson.org 5. Prophase I: preparing chromosomes for segregation in the developing oocyteRachel Harney, Benjamin Alleva, Sarit SmolikovSarit Smolikov saritsmol@gmail.com 6. Translational control of germ cell decisionsKumari Pushpa, Amaresh Chaturbedi, Ganga Anil Kumar and Kuppuswamy SubramaniamK Subramaniam subbu@iitm.ac.in 7. Prostagladin signaling from oocyte to spermHieu Dinh Hoang and Michael MillerMichael Miller mamiller@uab.edu 8. Cell fate maintenance and reprogramming during the oocyte-to-embryotransition'Christina Fassnacht and Rafal CioskRafal Ciosk rafal.ciosk@fmi.ch 9. Maternal to zygotic transitions across evolutionRueyling Lin rueyling.lin@utsouthwestern.edu 10 Cell cycle regulation in oocytesKubiak JZ and Borsuk EUniversity of Rennes, FranceJacek Kubiak. jacek.kubiak@univ-rennes1.fr 11 Oocyte activation and fertilization: crucial sperm and oocyte factorsMarc Yeste, Celine Jones, Siti N. Amdani, Kevin CowardUniversity of OxfordMarc Yeste. marc.yeste@obs-gyn.ox.ac.uk
Автор: Benjamin Bonavida; Salem Chouaib Название: Resistance of Cancer Cells to CTL-Mediated Immunotherapy ISBN: 3319178067 ISBN-13(EAN): 9783319178066 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.
Описание: This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.
Автор: T. Zollner; Harald Renz; Khusru Asadullah Название: Animal Models of T Cell-Mediated Skin Diseases ISBN: 3642422055 ISBN-13(EAN): 9783642422058 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character.
Автор: Jean-Francois Jeannin Название: Lipid A in Cancer Therapy ISBN: 1461424976 ISBN-13(EAN): 9781461424970 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The work needed to develop lipid A as an effective anti-cancer agent lies ahead in the near future. This volume is a timely contribution and provides a much needed up-to-date overview of the chemical, biological and physiological aspects of lipid A.
Автор: Baohong Zhang; Edmund J. Stellwag Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 149395749X ISBN-13(EAN): 9781493957491 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent stem cell research has revealed that miRNA and RNAi-mediated gene regulation is one of the vital determinates controlling the state of cell differentiation, with the small RNAs serving as key elements involved in regulatory network control of pluripotent cell fate determination. In RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications, expert authors from laboratories across the globe contribute an accessible compendium of up-to-date, proven methods focused on the study of the titular topic. Divided into three sections, the book first gives a brief introduction to RNAi and miRNAs in stem cells, with a focus on the current status of research and future perspectives, then it continues with detailed methods and protocols for RNAi screening, transfection, and the knockdown of specific genes and pathways in several animal species, including humans and mice, concluding with a section on recently developed methods for identification of miRNAs, including a general protocol for preparation and analysis of miRNA libraries for deep sequencing, knock down of a specific gene using miRNA-based shRNA, and miRNA expression analysis using qRT-PCR. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes highlighting tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications serves as a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and the exciting areas of medicine, including regenerative medicine, aging, cancer, and neurological disorders, that can be advanced through this expanding area of research.
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