Описание: In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest: the release of exosomes. In cancer, tumor exosomes are involved in various aspects of pathogenesis, including proliferation, immunosuppression, and metastasis. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. They are also being studied as prognostic markers for cancer.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Описание: This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.
Описание: This book explores recent findings on vesicle-based information transfer by exosomes. It provides an overview of exosomes biology and function and discusses the role of exosomal tetraspanins in tumor progression.
Автор: Swathi Arur Название: Signaling-Mediated Control of Cell Division ISBN: 3319448196 ISBN-13(EAN): 9783319448190 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. Role of chromatin modifications in germline stem cell differentiationPooja Flora, Maitreyi Upadhyay, Alicia McCarthy, Prashanth Rangan Prashanth Rangan prangan@albany.edu 2. Regulation of the balance between proliferation and differentiation in germline stem cells.Ramya Singh and David HansenDavid Donald Hansen dhansen@ucalgary.ca 3. Control of germ line stem cell lineages by diet and physiologyKaitlyn Laws and Daniela Drummond-BarbosaDaniela Barbosa dbarbosa@jhu.edu 4. Signal-mediated regulation of meiotic prophase I during oogenesisKenneth Trimmer and Swathi ArurSwathi Arur sarur@mdanderson.org 5. Prophase I: preparing chromosomes for segregation in the developing oocyteRachel Harney, Benjamin Alleva, Sarit SmolikovSarit Smolikov saritsmol@gmail.com 6. Translational control of germ cell decisionsKumari Pushpa, Amaresh Chaturbedi, Ganga Anil Kumar and Kuppuswamy SubramaniamK Subramaniam subbu@iitm.ac.in 7. Prostagladin signaling from oocyte to spermHieu Dinh Hoang and Michael MillerMichael Miller mamiller@uab.edu 8. Cell fate maintenance and reprogramming during the oocyte-to-embryotransition'Christina Fassnacht and Rafal CioskRafal Ciosk rafal.ciosk@fmi.ch 9. Maternal to zygotic transitions across evolutionRueyling Lin rueyling.lin@utsouthwestern.edu 10 Cell cycle regulation in oocytesKubiak JZ and Borsuk EUniversity of Rennes, FranceJacek Kubiak. jacek.kubiak@univ-rennes1.fr 11 Oocyte activation and fertilization: crucial sperm and oocyte factorsMarc Yeste, Celine Jones, Siti N. Amdani, Kevin CowardUniversity of OxfordMarc Yeste. marc.yeste@obs-gyn.ox.ac.uk
Автор: Wolf H. Fridman Название: Cell-Mediated Effects of Immunoglobulins ISBN: 1461285011 ISBN-13(EAN): 9781461285014 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Shedding light on the relationship between violence and contemporary society, this volume explores the distinctive but little-known theories of violence in the work of Georges Bataille and Jean Baudrillard, applying these to a range of violent events - events often labelled `inexplicable` - in order to show how even the most extreme of acts can be seen as socially meaningful.
Автор: Wolf H. Fridman Название: Cell-Mediated Effects of Immunoglobulins ISBN: 0412118211 ISBN-13(EAN): 9780412118210 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: All coordination between cells, organs, and organisms depends on successful biocommunicative processes.
Автор: Daniel G.S. Capelluto Название: Lipid-mediated Protein Signaling ISBN: 9400763301 ISBN-13(EAN): 9789400763302 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells.
Автор: Benjamin Bonavida; Salem Chouaib Название: Resistance of Cancer Cells to CTL-Mediated Immunotherapy ISBN: 3319178067 ISBN-13(EAN): 9783319178066 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.
Автор: Devendra K. Choudhary; Ajit Varma Название: Microbial-mediated Induced Systemic Resistance in Plants ISBN: 9811003874 ISBN-13(EAN): 9789811003875 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. Changes in phytochemicals in response to rhizospheric microorganisms infection Mehrnaz Hatami, Mansour Ghorbanpour 2. Bacillus-mediated induced systemic resistance (ISR) against Fusarium corm rot Shanu Magotra, Deepika Trakroo, Sneha Ganjoo and Jyoti Vakhlu 3. Plant growth-promoting rhizobacteria: key mechanisms of action Mбrcia do Vale Barreto Figueiredo, Aurenнvia Bonifacio, Artenisa Cerqueira Rodrigues, Fabio Fernando de Araujo 4. Priming of plant defense and plant growth in disease challenged crops using microbial consortia Murugan Kumar, Nanjappan Karthikeyan, and Radha Prasanna 5. Seed priming mediated induced disease resistance in arid zone plants Rakesh Pathak, Praveen Gehlot and S.K. Singh 6. Trichoderma secondary metabolites: their biochemistry and possible role in disease management Anita Surendra Patil, Surendra Rajaram Patil and Hariprasad Madhukarrao Paikrao 7. Induced systemic resistance in rice Kalaivani K. Nadarajah 8. Plant growth promoting rhizobacteria mediated acquired systemic resistance in plants against pests and diseases S.K. Singh, Rakesh Pathak and Vipin Chaudhary 9. Acyl homoserine lactone producing rhizobacteria-elicit systemic resistance in plants Ganga Viswanath, Jegan Sekar, and V.R. Prabhavathy 10. Biological Control of chickpea Fusarium wilt using rhizobacteria "PGPR" Souad Zaim, Lakhdar Belabid, Bassam Bayaa 11. AM fungal effect on the growth of selective dicot and monocot plants B. Sadhana*, P. K. Monica and S. Siva Sankari 12. Trichoderma spp.: Efficient Inducers of Systemic Resistance in Plants Kartikay Bisen, Chetan Keswani, J. S. Patel, B. K. Sarma, H. B. Singh 13. Induced systemic resistance by rhizospehric microbes Manoj Kumar, Priyanku Teotia, Ajit Varma, Narendra Tuteja, and Vivek Kumar 14. Combinations of plant growth-promoting rhizobacteria (PGPR) for initiation of systemic resistance against tree diseases Vivek Kumar, Ajit Varma Narendra Tuteja and Manoj Kumar 15. Plant growth promoting microbial-mediated induced systemic resistance in plants: induction, mechanism and expression Shekhar Jain, Ajit Varma, Narendra Tuteja, D.K. Choudhary
Автор: JOSE ISAGANI B. JANAIRO Название: Peptide-Mediated Biomineralization ISBN: 9811008574 ISBN-13(EAN): 9789811008573 Издательство: Springer Рейтинг: Цена: 7836.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes recent advances in peptide-mediated biomineralization and how this method was able to create improved catalysts through minor tweaks in the system.
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