Multiscale Modeling in Biomechanics and Mechanobiology, Suvranu De; Wonmuk Hwang; Ellen Kuhl
Автор: Suvranu De; Wonmuk Hwang; Ellen Kuhl Название: Multiscale Modeling in Biomechanics and Mechanobiology ISBN: 1447165985 ISBN-13(EAN): 9781447165989 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.
Автор: Amit Gefen; Dafna Benayahu Название: The Mechanobiology of Obesity and Related Diseases ISBN: 3319376268 ISBN-13(EAN): 9783319376264 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mechanical behavior and properties of adipose tissue.- Mathematical models of adipose tissue dynamics.- Mechanical stretching and signaling pathways in adipogenesis- Role of mechanical stimulations in directing mesenchymal stem cell adipogenesis.- The vicious cycle of estrogen consumption and obesity: The role of mechanotransduction.- Extracellular matrix remodeling and mechanical stresses as modulators of adipose tissue metabolism and inflammation.- The Impact of Obesity and Weight Loss on Gait in Adults.- Excessive Weight Bearing Compromises Foot Structure and Function across the Lifespan.- Obesity, Osteoarthritis and Aging: The Biomechanical Links.- Impaired neutrophil mechanoregulation by fluid flow: A potential contributing factor for microvascular dysfunction in obesity.- Mechanotransduction and the myogenic response in diabetes.- Role of adipose cells in tumor microenvironment.
Автор: Suvranu De; Farshid Guilak; Mohammad Mofrad Название: Computational Modeling in Biomechanics ISBN: 9400790988 ISBN-13(EAN): 9789400790988 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a glimpse of the diverse and important roles that modern computational technology is playing in various areas of biomechanics. It includes unique chapters on ab initio quantum mechanical, molecular dynamic and scale coupling methods.
Автор: Tim McGloughlin Название: Biomechanics and Mechanobiology of Aneurysms ISBN: 3642270751 ISBN-13(EAN): 9783642270758 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. It details key factors influencing aneurysm behavior and treatment.
Автор: Peter Pivonka Название: Multiscale Mechanobiology of Bone Remodeling and Adaptation ISBN: 3319588435 ISBN-13(EAN): 9783319588438 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
Автор: Gefen Amit Название: Multiscale Computer Modeling in Biomechanics and Biomedical ISBN: 3642364810 ISBN-13(EAN): 9783642364815 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the state-of-the-art in multiscale computer modeling, examining both its accomplishments and its challenges. Helps connect traditional biomedical engineering at the organ and tissue scale with cellular and molecular bioengineering.
Описание: This book reviews the state-of-the-art in multiscale computer modeling, examining both its accomplishments and its challenges. Helps connect traditional biomedical engineering at the organ and tissue scale with cellular and molecular bioengineering.
Автор: Tzung K Hsiai Название: Hemodynamics And Mechanobiology Of Endothelium ISBN: 9814280410 ISBN-13(EAN): 9789814280419 Издательство: World Scientific Publishing Рейтинг: Цена: 19008.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The investigation of vascular biology and cardiovascular medicine is made possible by the use of tissue engineering, nanotechnology and stem cell research. This book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress.
The Mechanophysiololgy of Stress Fractures in Military Recruits.- Traumatic Brain Injury in the Military: Biomechanics and Finite Element Modelling.- Modeling Skeletal Injuries in Military Scenarios.- Biomechanics of Eye Injury in the Military.- The Biomechanical Basis for Increased Risk of Overuse Musculoskeletal Injuries in Female Soldiers.
Автор: A. Wagoner Johnson; Brendan Harley Название: Mechanobiology of Cell-Cell and Cell-Matrix Interactions ISBN: 1489973796 ISBN-13(EAN): 9781489973795 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines interactions between cells and their local extracellular environment, exploring how these may mediate cell behavior. Topics include integrin-ligand interactions; cooperative mechanisms of cell-matrix interactions and quantitative methods.
Автор: Amit Gefen; Dafna Benayahu Название: The Mechanobiology of Obesity and Related Diseases ISBN: 3319093355 ISBN-13(EAN): 9783319093352 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mechanical behavior and properties of adipose tissue.- Mathematical models of adipose tissue dynamics.- Mechanical stretching and signaling pathways in adipogenesis- Role of mechanical stimulations in directing mesenchymal stem cell adipogenesis.- The vicious cycle of estrogen consumption and obesity: The role of mechanotransduction.- Extracellular matrix remodeling and mechanical stresses as modulators of adipose tissue metabolism and inflammation.- The Impact of Obesity and Weight Loss on Gait in Adults.- Excessive Weight Bearing Compromises Foot Structure and Function across the Lifespan.- Obesity, Osteoarthritis and Aging: The Biomechanical Links.- Impaired neutrophil mechanoregulation by fluid flow: A potential contributing factor for microvascular dysfunction in obesity.- Mechanotransduction and the myogenic response in diabetes.- Role of adipose cells in tumor microenvironment.
Автор: A. Holzapfel Название: Biomechanics: Trends in Modeling and Simulation ISBN: 3319414739 ISBN-13(EAN): 9783319414737 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues.The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
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