Molecular Pathogenesis of Colorectal Cancer, Kevin M. Haigis, Ph.D.
Автор: Kevin M. Haigis, Ph.D. Название: Molecular Pathogenesis of Colorectal Cancer ISBN: 1461484111 ISBN-13(EAN): 9781461484110 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book identifies and characterizes targetable oncogenic pathways in colorectal cancer. It explores the current and future prospects for targeting these pathways therapeutically and presents emerging technologies for identifying new cancer related genes.
Автор: Rudolf Rott; Werner Goebel Название: Molecular Basis of Viral and Microbial Pathogenesis ISBN: 364273216X ISBN-13(EAN): 9783642732164 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The avail- ability of new genetic and immunological techniques, especially recom- binant DNA methods and monoclonal antibody technology, has provided powerful tools for unravelling the genetic, biochemical and immunologi- cal basis of viral and microbial pathogenesis.
Автор: Beauchemin Название: Metastasis of Colorectal Cancer ISBN: 9048188326 ISBN-13(EAN): 9789048188321 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers colon cancer metastasis from fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, and more.
Автор: Gregory Название: Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy ISBN: 3319394045 ISBN-13(EAN): 9783319394046 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews.
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
Описание: Large-section histopathology widens your perspectives...Correct diagnosis and staging are essential in determining the appropriate therapy of colorectal carcinoma, one of the most common malignancies in America and Europe. As medical science continues to develop rapidly, histopathology remains an essential part of diagnosis in most malignant diseases. In this era of interdisciplinary medicine, the role of pathology has expanded to provide images that easily correlate with endoscopic, radiological, or operative findings.In this remarkable atlas, Tibor Tot presents colon pathology in large histological sections, with cross-sections of entire tumors in their anatomic environments and their circumferential surgical margins. These unique images form a guide to diagnosis, tumor typing and staging according to TNM criteria. They help to assess the completeness of a surgical excision and to understand the heterogeneity of colorectal carcinomas. Features:- Cases illustrated in two-page spreads with clinical information, conventional histopathology, and large-section histology images enlarged to almost a full page. - Pathology seen in the context of surrounding tissues- The margins of malignant tumors visible in their entirety- Schematic guides to interpretation of the large-section images - Emphasis on diagnostic advantages of using large section technique- Technical guidelines for obtaining large-section histopathology specimensThis atlas is the result of seven years of studying almost 2,000 cases of colorectal carcinoma and other intestinal lesions and is highly recommended for pathologists, radiologists, surgeons, and oncologists alike.
Автор: Hilbi Название: Molecular Mechanisms in Legionella Pathogenesis ISBN: 3642405908 ISBN-13(EAN): 9783642405907 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines different facets of Legionnaires` disease, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses.
Описание: This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide.
Описание: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development.
Part 1. Introduction.- 1. History of Research on Pathogenesis of Idiopathic Nephrotic Syndrome.- Part 2. Minimal-change nephrotic syndrome (MCNS).- 2. Hemopexin in Minimal Change Nephrotic Syndrome.- 3. Angiopoietin-like-4 (Angptl4) in MCNS.- 4. Co-stimulatory molecule CD80 (B7.1) in MCNS.- 5. Energy and Mammalian target of rapamycin complex 1 (mTORC1) in minimal change nephrotic syndrome.- 6. The role of c-mip in the pathogenesis of Minimal Change Nephrotic Syndrome.- 7. REGULATORY T-CELLS AND OXIDATIVE STRESS IN MINIMAL CHANGE NEPHROPATHY.- 8. CYTOKINES AS ACTIVE FACTORS IN MINIMAL CHANGE NEPHROTIC SYNDROME.- Part 3. Focal segmental glomerulosclerosis (FSGS).- 9. Soluble urokinase-type plasminogen activator receptor (suPAR) in Focal Segmental Glomerulosclerosis.- 10. CYTOKINES AS ACTIVE FACTORS IN FOCAL SEGMENTAL GLOMERULOSCLEROSIS.- Part 4. Idiopathic Membranous Nephropathy (IMN).- 11. M-Type Phospholipase A2 Receptor (PLA2R) and Thrombospondin Type-1 Domain-Containing 7A (THSD7A) in Membranous Nephropathy.- 12. Cationic Bovine Serum Albumin as Cause of Membranous Nephropathy: From Mice to Men.- Part 5. Treatment in Idiopathic Nephrotic Syndrome.- 13. Podocytes as a direct target of drugs used in Idiopathic Nephrotic Syndrome.
Автор: J.E. Vanderplank Название: Genetic and Molecular Basis of Plant Pathogenesis ISBN: 3642669670 ISBN-13(EAN): 9783642669675 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As befits a volume in the Advanced Series in Agricultural Sciences, this book was written with problems of practical agriculture in mind. Half the book could not have been written 20 years ago, even if there had then been available all the literature that has since accumulated on the genetics and chemistry of plant disease.
Автор: Benjamin Bonavida Название: Nitric Oxide and Cancer: Pathogenesis and Therapy ISBN: 3319136100 ISBN-13(EAN): 9783319136103 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.
Автор: Isabelle Mercier; Jean-Fran?ois Jasmin; Michael P. Название: Caveolins in Cancer Pathogenesis, Prevention and Therapy ISBN: 1493901346 ISBN-13(EAN): 9781493901340 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Caveolins play an important role in the pathogenesis of multiple cancers. This volume focuses mainly on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers. It also studies the role of Caveolin-3 in breast cancer.
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