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Malaria Vaccines, Ashley Vaughan


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Автор: Ashley Vaughan
Название:  Malaria Vaccines
ISBN: 9781493949021
Издательство: Springer
Классификация:
ISBN-10: 1493949020
Обложка/Формат: Paperback
Страницы: 305
Вес: 0.61 кг.
Дата издания: 23.08.2016
Серия: Methods in Molecular Biology
Язык: English
Размер: 254 x 178 x 17
Основная тема: Biomedicine
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The chapters within this book talk about interventions concerning all aspects of life cycle progression--measuring antibody responses to blood stage parasite survival, the T Cell responses engendered by attenuated sporozoite vaccinations, and the unique effect on transmission of antibodies that target the mosquito stage of the life cycle.


Novel Strategies in the Design and Production of Vaccines

Автор: Sara Cohen; Avigdor Shafferman
Название: Novel Strategies in the Design and Production of Vaccines
ISBN: 0306452111 ISBN-13(EAN): 9780306452116
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Proceedings of the 39th OHOLO Conference held in Eilat, Israel, May 7-11, 1995.

New Vaccines and Chemotherapy

Автор: Edouard Kurstak; R.G. Marusyk; F.A. Murphy; M.H.V.
Название: New Vaccines and Chemotherapy
ISBN: 0306426595 ISBN-13(EAN): 9780306426599
Издательство: Springer
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Цена: 34799.00 р.
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Описание: Viral Vaccines Joseph L. These reports, plus a third on Vaccine Supply and Innovation (1985a), should be required reading for all those in both the public and the private sector who have a responsibility or interest in vaccines for the prevention of human disease.

Genomics,Proteomics & Vaccines.2004

Автор: Grandi
Название: Genomics,Proteomics & Vaccines.2004
ISBN: 0470856165 ISBN-13(EAN): 9780470856161
Издательство: Wiley
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Цена: 29296.00 р.
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Описание: The complete genome sequences of many bacteria are available, and comparisons of pathogenic strains with non pathogenic relatives are becoming more common. This will enable researchers to target vaccine development towards specific gene products that traditional approaches of vaccine research failed to discover.

Vaccines: Are they Worth a Shot?

Автор: Andrea Grignolio; Joan Rundo
Название: Vaccines: Are they Worth a Shot?
ISBN: 3319681052 ISBN-13(EAN): 9783319681054
Издательство: Springer
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Цена: 4191.00 р.
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Описание: 1. The parents of unvaccinated children

1.1. The 80s, the beginning of the crisis (or resistance)

1.2. Education about risk

1.3. Social changes: The doctor-patient relationship in jeopardy

1.4. Unexpected impact of late fecundity

2. A brief history of the anti-vaccination movements

2.1. The anti-vaccination movements between 1700 and 1800: Roots of obligation and objection

2.2. The anti-vaccination movements in 1900: Media and politics

3. Web alarms: autism, mercury and immune overload

3.1. Conspiracy on the Internet: separating fact from fiction

3.2. Economic criticism: Big Pharma and the allure of patents

3.3. Logic errors: the precautionary principle and the equal balance mistake

3.4. False or manipulated data: Autism

3.5. Prejudices and ideologies: Purported overload and weakening of the immune system

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4. The antivax "experts" five ways to recognize them

4.1. Alternative philosophies: homeopathy, anthroposophy and Waldarf -Steiner schools

4.2. The "alternative therapies" Five clues that reveal a charlatan

5. Past, present, and future of vaccines

5.1. Evolutionary history of naturally acquired immunity

5.2. Artificially acquired immunity: success and safety of vaccines

5.3. Therapeutic vaccines of the future: cancer and neurodegenerative diseases

6. Conclusions

6.1. A new alliance between scientists and citizens for a "knowledge society"

6.2. Some tools for good communication strategies to combat anti-vaccination resistance
Vaccines and Autoimmunity

Автор: Yehuda Shoenfeld,Nancy Agmon–Levin
Название: Vaccines and Autoimmunity
ISBN: 1118663438 ISBN-13(EAN): 9781118663431
Издательство: Wiley
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Цена: 22485.00 р.
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Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.

Anti-Idiotypic Vaccines

Автор: Pierre-Andre Cazenave
Название: Anti-Idiotypic Vaccines
ISBN: 1461277507 ISBN-13(EAN): 9781461277507
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out.

Lyophilized Biologics and Vaccines

Автор: Dushyant Varshney; Manmohan Singh
Название: Lyophilized Biologics and Vaccines
ISBN: 1493955683 ISBN-13(EAN): 9781493955688
Издательство: Springer
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Цена: 16070.00 р.
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Описание: This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide the reader through all crucial aspects, from biophysical and chemical stability considerations of proteins, analytical methods, advances in controlled ice nucleation and quality-by-design approaches, alternate drying technology, to latest regulatory, packaging and technology transfer considerations to develop a stable, safe and effective therapeutic protein, vaccine and biotechnology products. Lyophilized Biologics and Vaccines: Modality-Based Approaches is composed of four sections with a total of 17 chapters. It serves as a reference to all critical assessments and steps from early pre-formulation stages to product launch: * Provides recent understanding of heterogeneity of protein environment and selection of appropriate buffer for stabilization of lyophilized formulations * Details the latest developments in instrumental analysis and controlled ice nucleation technology * Explains in-depth lyophilized (or dehydrated) formulation strategies considering diverse modalities of biologics and vaccines, including plasmid DNA and lipid-based therapeutics * Details an exhaustive update on quality-by-design and process analytical technology approaches, illustrated superbly by case studies and FDA perspective * Provides the latest detailed account of alternate drying technologies including spray drying, bulk freeze-drying and crystallization, supported exceptionally by case studies * Provides a step-by-step guide through critical considerations during process scale-up, technology transfer, packaging and drug delivery device selection, for a successful lyophilization process validation, regulatory submission and product launch Chapters are written by one or more world-renowned leading authorities from academia, industry or regulatory agencies, whose expertise cover lyophilization of the diverse modalities of biopharmaceuticals. Their contributions are based on the exhaustive review of literature coupled with excellent hands-on experiences in laboratory or GMP setup, making this an exceptional guide to all stages of lyophilized or dehydrated product development.

DNA Vaccines

Автор: Douglas B. Lowrie; Robert Whalen
Название: DNA Vaccines
ISBN: 0896035808 ISBN-13(EAN): 9780896035805
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This collection of review articles summarize how to develop and employ DNA vaccines, what can be expected from their clinical development, and what is known about how they work. Topics include immunostimulatory sequences, cytokines, and practical advice for general and specific applications.

Vaccines

Автор: Gregory Gregoriadis; Brenda McCormack; Anthony C.
Название: Vaccines
ISBN: 0306452839 ISBN-13(EAN): 9780306452833
Издательство: Springer
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Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1994.

Cancer Vaccines

Автор: Michael J.P. Lawman; Patricia D. Lawman
Название: Cancer Vaccines
ISBN: 1493951955 ISBN-13(EAN): 9781493951956
Издательство: Springer
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Цена: 21661.00 р.
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Описание:

Part I: Manipulation and Modification of Immune Cells: Dendritic Cells

1. Single Step Antigen Loading and Maturation of Dendritic Cells Through mRNA Electroporation of a Tumor-Associated Antigen and a TriMix of Costimulatory Molecules

Daphnй Benteyn, An M.T. Van Nuffel, Sofie Wilgenhof, and Aude Bonehill

2. Generation of Multiple Peptide Cocktail-Pulsed Dendritic Cells as a Cancer Vaccine

Hyun-Ju Lee, Nu-Ri Choi, Manh-Cuong Vo, My-Dung Hoang, Youn-Kyung Lee, and Je-Jung Lee

3. Pulsing Dendritic Cells with Whole Tumor Cell Lysates

Laura Alaniz, Manglio M. Rizzo, and Guillermo Mazzolini

4. Antigen Trapping by Dendritic Cells for Anti-Tumor Therapy

Chiranjib Pal

5. Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens

Manglio M. Rizzo, Laura Alaniz, and Guillermo Mazzolini

6. Tumor Antigen/Cytokine-Pulsed Dendritic Cells in Therapy Against Lymphoma

Sumit K. Hira, Deepak Verma, and Partha P. Manna

7. Dendritic Cells Primed with Protein-Protein Fusion Adjuvant

Liying Wang and Yongli Yu

8. Antigen-Specific mRNA Transfection of Autologous Dendritic Cells

Fabian Benencia

9. Electroporation of Dendritic Cells with Autologous Total RNA from Tumor Material

Francesca Milano and K.K. Krishnadath

10. Dendritic Cells Transfected with Adenoviral Vectors as Vaccines

Joseph Senesac, Dmitry Gabrilovich, Samuel Pirruccello, and James E. Talmadge

11. Genetic Modification of Dendritic Cells with RNAi

Xiao-Tong Song

12. Fast Monocyte-Derived Dendritic Cells-Based Immunotherapy

Gamal Ramadan

13. Intratumoral Injection of BCG-CWS Pretreated Dendritic Cells Following Tumor Cryoablation

Naoshi Kawamura, Masaru Udagawa, Tomonobu Fujita, Toshiharu Sakurai, Tomonori Yaguchi, and Yutaka Kawakami

14. Exploiting the CD1d-iNKT Cell Axis for Potentiation of DC-Based Cancer Vaccines

Roeland Lameris, Famke L. Schneiders, Tanja D. de Gruijl, and Hans J. van der Vliet

Part II: Manipulation and Modification of Immune Cells: T Lymphocytes and NK Cells

15. Modification of T Lymphocytes to Express Tumor Antigens

Aaron E. Foster and Xiao-Tong Song

16. Genetic Modification of Mouse Effector and Helper T Lymphocytes Expressing a Chimeric Antigen Receptor

Liza B. John, Tess M. Chee, David E. Gilham, and Phillip K. Darcy

17. Genetic Modification of Cytotoxic T Lymphocytes to Express Cytokine Receptors

Serena K. Perna, Barbara Savoldo, and Gianpietro Dotti

18. Monitoring the Frequency and Function of Regulatory T Cells and Summary of the Approaches Currently Used to Inhibit Regulatory T Cells in Cancer Patients

Chiara Camisaschi, Marcella Tazzari, Licia Rivoltini, and Chiara Castelli

19. Cytokine Activation of Natural Killer Cells

Syh-Jae Lin, Pei-Tzu Lee, and Ming-Ling Kuo

Part III: Manipulation and Modification of Tumor Cells

20. Loading of Acute Myeloid Leukemia Cells with Poly(I: C) by Electroporation

Eva Lion, Charlotte M. de Winde, Viggo F.I. Van Tendeloo, and Evelien L.J.M. Smits

21. Autologous Tumor Cells Engineered to Express Bacterial Antigens

Vijayakumar K. Ramiya, Maya M. Jerald, Patricia D. Lawman, and Michael J.P. Lawman

22. Tumor Cell Transformation Using Antisense Oligonucleotide

Mohamed R. Akl and Nehad M. Ayoub

23. The Direct Display of Costimulatory Proteins on Tumor Cells as a Means of Vaccination for Cancer Immunotherapy

Haval Shirwan, Esma S. Yolcu, Rajesh K. Sharma, Hong Zaho, and Orlando Grimany-Nuno

Part IV: Manipulation of Immune/Tumor Interactions

24. Cloning Variable

Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines

Автор: Darren R. Flower; Yvonne Perrie
Название: Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines
ISBN: 1489997954 ISBN-13(EAN): 9781489997951
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book details the discovery of antigens and adjuvants within the context of reverse vaccinology. It explores ways to make vaccines more effective.

Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines

Автор: Manmohan Singh
Название: Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines
ISBN: 1489992286 ISBN-13(EAN): 9781489992284
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This book outlines the critical steps that need to be considered for successful development of various types of nanoparticulate delivery systems for vaccine antigens. Coverage includes clinical evaluations with these novel vaccine technologies.


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