Описание: The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.
Автор: Terrell L. Hill Название: Linear Aggregation Theory in Cell Biology ISBN: 1461291348 ISBN-13(EAN): 9781461291343 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known ofthe chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis oflife is unified.
This thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own work. Amyloid proteins are highly complex, and this research provides unparalleled insights, especially with regard to the origin of cytotoxicity and to developing technologies for early detection, revealing in detail the molecular mechanisms behind hIAPP behavior. Several studies within the thesis answer difficult questions which promote future research into the properties of amyloid proteins.
Автор: Sandal, Massimo Название: Early Stage Protein Misfolding and Amyloid Aggregation ISBN: 012812251X ISBN-13(EAN): 9780128122518 Издательство: Elsevier Science Рейтинг: Цена: 29476.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.
The series has a worldwide readership and maintains a high standard by publishing invited articles on important and timely topics as authored by prominent cell and molecular biologists.
Автор: T. Isobe Название: Amyloid and Amyloidosis ISBN: 1475703007 ISBN-13(EAN): 9781475703009 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
This book reviews current research on the important processes involved in neurodegenerative diseases (e.g. Alzheimer's disease) and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors, and gives readers a fundamental understanding of the underlying oligomerization and aggregation processes of these diseases from both computational and experimental points of view.
Автор: Vladimir N. Uversky; Anthony Fink Название: Protein Misfolding, Aggregation and Conformational Diseases ISBN: 1441938516 ISBN-13(EAN): 9781441938510 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.
Описание: Focuses on the aggregation of recombinant proteins in bacterial cells in the form of inclusion bodies and on their use in biotechnological and medical applications. This title provides a large overview of protein folding and aggregation, including cell biology and methodological aspects.
Автор: Einar M. Sigurdsson; Miguel Calero; Mar?a Gasset Название: Amyloid Proteins ISBN: 149395623X ISBN-13(EAN): 9781493956234 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In its new edition, this Methods in Molecular Biology (TM) book offers protocols for preparing amyloid and its precursors, cell culture models, extraction from tissue, detection in vitro and in vivo and nontransgenic methods for developing amyloid mouse models.
Автор: J. Robin Harris; Falk Fahrenholz Название: Alzheimer`s Disease: Cellular and Molecular Aspects of Amyloid beta ISBN: 1461498414 ISBN-13(EAN): 9781461498414 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: To understand Alzheimer's disease (AD) is one of the major thrusts of present-day clinical research, strongly supported by more fimdamental cellular, biochemical, immunological and structural studies. It is these latter that receive attention within this book. This compilation of 20 chapters indicates the diversity of work currently in progress and summarizes the current state of knowledge. Experienced authors who are scientifically active in their fields of study have been selected as contributors to this book, in an attempt to present a reasonably complete survey of the field. Inevitably, some exciting topics for one reason or another have not been included, for which we can only apologize. Standardization of terminology is often a problem in science, not least in the Alzheimer field; editorial effort has been made to achieve standardization between the Chapters, but some minor yet acceptable personal / author variation is still present, i. e. P-amyloid/amyloid-P; Ap42/Apl-42/APi. 42! The book commences with a broad survey of the contribution that the range of available microscopical techniques has made to the study of Alzheimer's amyloid plaques and amyloid fibrillogenesis. This chapter also serves as an Introduction to the book, since several of the topics introduced here are expanded upon in later chapters. Also, it is significant to the presence of this chapter that the initial discovery of brain plaques, by Alois Alzheimer, utilized light microscopy, a technique that continues to be extremely valuable in present-day AD research.
Автор: Jacob B Natvig; ?ystein F?rre; Gunnar Husby; Anne Название: Amyloid and Amyloidosis 1990 ISBN: 9401054509 ISBN-13(EAN): 9789401054508 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the VIth International Symposium on Amyloidosis, held in Oslo, Norway, 5-8 August 1990.
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