Non-coding RNAs and Cancer, Muller Fabbri

Название: Long non-coding rnas in human disease
ISBN: 3319239066 ISBN-13(EAN): 9783319239064
Издательство: Springer
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Цена: 19591.00 р.
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Описание: The role oflncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, pastretroelements integrated within the human genome, as well as the role thesepseudogene-derived lncRNAs play in cancer development are discussed in detail.

Автор: Song
Название: The Long and Short Non-coding RNAs in Cancer Biology
ISBN: 9811014965 ISBN-13(EAN): 9789811014963
Издательство: Springer
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Цена: 23508.00 р.
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Описание: The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

Автор: Slaby
Название: Non-coding RNAs in Colorectal Cancer
ISBN: 3319420577 ISBN-13(EAN): 9783319420578
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.

Автор: Muller Fabbri
Название: Non-coding RNAs and Cancer
ISBN: 146148443X ISBN-13(EAN): 9781461484431
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book provides essential information of the biogenesis, physiology and de-regulation of non-coding RNAs in cancer. It guides the reader to the most widely and effectively used bioinformatic approaches to the study of miRNAs.

Автор: Volker A. Erdmann; Jan Barciszewski
Название: Non Coding RNAs in Plants
ISBN: 3642269990 ISBN-13(EAN): 9783642269998
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Discovered just 20 years ago, ncRNAs have been dubbed the `secret regulators` of cells. Only recently has their function in plants been investigated. In this book leading researchers relate recent discoveries about the role played by small ncRNA in plants.

Автор: ?ur?ica Ugarkovi?
Название: Long Non-Coding RNAs
ISBN: 364226655X ISBN-13(EAN): 9783642266553
Издательство: Springer
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Цена: 23508.00 р.
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Описание: Long Non-Coding RNAs provides an overview of the rapidly advancing field, and describes the epigenetic and non-epigenetic mechanisms by which they regulate various biological functions in model systems. Readers will find a discussion of the role of ncRNAs in sex chromosome dosage compensation, and more.

Автор: Gordon G. Carmichael
Название: Regulatory Non-Coding RNAs
ISBN: 1493913689 ISBN-13(EAN): 9781493913688
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Regulatory Non-Coding RNAs: Methods and Protocols offers a collection of methods for those interested in the discovery, localization, and functional analysis of these non-coding transcripts that have the potential and ability to orchestrate and control gene expression.

Автор: Mathieu Rederstorff
Название: Small Non-Coding RNAs
ISBN: 1493925466 ISBN-13(EAN): 9781493925469
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Small Non-Coding RNAs

Автор: Yi Feng; Lin Zhang
Название: Long Non-Coding RNAs
ISBN: 1493933760 ISBN-13(EAN): 9781493933761
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA.

Автор: Ahmad M. Khalil; Jeff Coller
Название: Molecular Biology of Long Non-coding RNAs
ISBN: 1493945289 ISBN-13(EAN): 9781493945283
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book examines key issues in lncRNA biology, including critical studies that have led to the discovery and annotation of lncRNAs in numerous species and the molecular mechanisms for a few lncRNA that have begun to emerge.

Автор: Gordon G. Carmichael
Название: Regulatory Non-Coding RNAs
ISBN: 1493941844 ISBN-13(EAN): 9781493941841
Издательство: Springer
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Цена: 13275.00 р.
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Описание: Regulatory Non-Coding RNAs: Methods and Protocols offers a collection of methods for those interested in the discovery, localization, and functional analysis of these non-coding transcripts that have the potential and ability to orchestrate and control gene expression.

Автор: Catherine M. Greene
Название: MicroRNAs and Other Non-Coding RNAs in Inflammation
ISBN: 3319382306 ISBN-13(EAN): 9783319382302
Издательство: Springer
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Цена: 18284.00 р.
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Описание: The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e.