Genetic Toxicology, James M. Parry; Elizabeth M. Parry
Автор: Harper Joyce C. Название: Preimplantation genetic diagnosis ISBN: 0521884713 ISBN-13(EAN): 9780521884716 Издательство: Cambridge Academ Рейтинг: Цена: 12862.00 р. 18374.00-30% Наличие на складе: Есть (1 шт.) Описание: Preimplantation genetic diagnosis (PGD) is a key technique in modern reproductive medicine. Originally developed to help couples who were at risk of transmitting single-gene genetic abnormalities to their children, the development of the FISH technique broadened chromosome analysis to include detection of more complex inherited abnormalities. The last decade has seen the development of aneuploidy screening (PGS) for infertile couples, using the same techniques as PGD but screening for as many chromosomes as possible. PGD has always been a controversial procedure and embryo manipulation and selection is still illegal in some countries. The second edition of this leading textbook describes all aspects of PGD, with chapters written by key international experts in the field. A must for anyone interested in learning more about PGD, it will be of interest to everyone working in the fields of IVF, genetic diagnosis, genetic counselling, and prenatal diagnosis - including clinicians, embryologists, nurses, and clinical scientists.
Автор: Fumio Matusmura Название: Toxicology of Insecticides ISBN: 1461295084 ISBN-13(EAN): 9781461295082 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The most rewarding aspect of writing a book is receiving encouraging comments from one`s colleagues, since one always wonders whether fair coverage was made of the work of others or whether some omissions were made.
Автор: Proudlock, Ray Название: Genetic Toxicology Testing ISBN: 0128007648 ISBN-13(EAN): 9780128007648 Издательство: Elsevier Science Рейтинг: Цена: 12462.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "
Genetic Toxicology Testing: A Laboratory Manual" presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory ad test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria.
An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. "Genetic Toxicology Testing: A Laboratory Manual" is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own. Offers practical and consistent guidance on the most commonly-performed tests and procedures in a genetic toxicology labDescribes standard genetic toxicology assays, their methodology, reagents, suppliers, and analysis of their resultsIncludes guidance on general approaches: formulation for in vitro assays, study monitoring, and Good Laboratory Practice (GLP)Serves as an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own lab
Автор: David Brusick Название: Principles of Genetic Toxicology ISBN: 1461576636 ISBN-13(EAN): 9781461576631 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field of genetic toxicology is a relatively new one which grew out of the studies of chemical mutagenesis and modern toxicology. Considering that systematic practices to detect chemical mutagenesis are only a little over thirty years old, this field has evolved very rapidly with an abundance of methods for identifying chemical mutagens.
Автор: D. Brusick Название: Principles of Genetic Toxicology ISBN: 0306425327 ISBN-13(EAN): 9780306425325 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field of genetic toxicology has gone through remarkable development in the seven years since the appearance of the first edition of Principles of Genetic Toxicology.
Автор: Michael D. Waters; F.Bernhard Daniel; Joellen Lewt Название: Genetic Toxicology of Complex Mixtures ISBN: 1468458523 ISBN-13(EAN): 9781468458527 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a symposium held in Washington, DC, July 4-7, 1989
Автор: D. Brusick Название: Principles of Genetic Toxicology ISBN: 1489919821 ISBN-13(EAN): 9781489919823 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field of genetic toxicology has gone through remarkable development in the seven years since the appearance of the first edition of Principles of Genetic Toxicology.
Автор: Mike Clements; Liz Roquemore Название: Stem Cell-Derived Models in Toxicology ISBN: 1493966596 ISBN-13(EAN): 9781493966592 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume brings together a diverse collection of stem cell-derived model-based toxicity assays, from those routinely used to those deemed to have considerable potential. With a focus on differentiated tissues, the chapters explore numerous cardiotoxicity applications as well as coverage of neurotoxicity, hepatotoxicity, and more. Written for the Methods in Pharmacology and Toxicology series, the contents of this book aim to enable adoption of these protocols in laboratories that are interested in entering the field as well as to facilitate the transfer of best practices between laboratories that are already actively pursuing these technologies.
Authoritative and cutting-edge, Stem Cell-Derived Models in Toxicology serves as a vital resource for researchers aiming to improve risk assessment in drug discovery and design.
Автор: George Parker Название: Immunopathology in Toxicology and Drug Development ISBN: 3319473840 ISBN-13(EAN): 9783319473840 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies, offers an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Автор: Zhu Название: High-Throughput Screening Assays in Toxicology ISBN: 1493963449 ISBN-13(EAN): 9781493963447 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on recently developed High Throughput Screening (HTS) assay protocols, many involved in the ToxCast and/or Tox21 initiatives, and the relevant HTS data analysis techniques. Divided into three sections, in vitro assays, in vivo assays, and computational techniques to analyze HTS data are all examined. Written for the highly successful Methods in Molecular Biology series, most chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, High Throughput Screening Assays in Toxicology serves as a valuable reference resource for translating new HTS techniques into standardized chemical toxicity assessment tools in order to advance modern toxicology research to a new era where HTS techniques can partially replace the prevailing animal models.
Автор: Xu Название: Predictive Toxicology in Drug Safety ISBN: 0521763649 ISBN-13(EAN): 9780521763646 Издательство: Cambridge Academ Рейтинг: Цена: 19800.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a handbook on drug discovery toxicology for scientists working in this field dedicated to the development of safe drugs. It provides information on the present knowledge of drug side effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology.
Автор: K.L. Kaiser Название: QSAR in Environmental Toxicology - II ISBN: 9401082464 ISBN-13(EAN): 9789401082464 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 2nd International Workshop on QSAR in Environmental Toxicology, held at McMaster University, Hamilton, Ontario, Canada, June 9-13, 1986
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