Àâòîð: Guido Massi Íàçâàíèå: Histological Diagnosis of Nevi and Melanoma ISBN: 3642373100 ISBN-13(EAN): 9783642373107 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 41925.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå: The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.
Àâòîð: Champney W. Scott Íàçâàíèå: New Antibiotic Targets ISBN: 1588299155 ISBN-13(EAN): 9781588299154 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 16769.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå: Examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. This volume features drug targets including peptide deformylase, ribosome formation, lipopolysaccharide and fatty acid biosynthesis and signal transduction pathways.
Cutaneous Melanoma: A Pocket Guide for Diagnosis and Management serves as an easy-to-consult, short, and schematic reference providing guidelines for diagnosing and managing melanoma in the context of various clinical scenarios. In the daily routine of a busy clinician, there is a need for schematic reference tools that allow quick consultation for immediate decisions. Melanoma is a deadly disease that should be promptly managed following precise and evidence-based guidelines.
The guide contains many schematics and figures, vastly outnumbering the pages dedicated to text. This guide follows the sequence of a real clinical setting, going from the first screening visit to the final stages of terminal patients.
Îïèñàíèå: This pocket book provides up-to-date guidance on the use of PET/CT in patients with melanoma, which is of rapidly growing importance due to the emergence of immunotherapy. The role of PET/CT in diagnostic workup, staging, treatment selection, prognostication, and follow-up is clearly explained. Imaging features are described and illustrated with the aid of a series of teaching cases, and attention is drawn to normal variants, artifacts, and pitfalls.
Readers will also find explanation of the relation of the clinical and pathological background to imaging and the value of PET/CT compared with conventional radiological imaging. The book is published within the Springer series Clinicians' Guides to Radionuclide Hybrid Imaging (compiled under the auspices of the British Nuclear Medicine Society) and will be an excellent asset for referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings.
Îïèñàíèå: Featuring advances in the field of melanoma pathology, this book contains sections on the genetics and cytogenetics of melanoma, the sentinel lymph node procedure, the AJCC TNM staging system for melanoma and the mechanisms of melanoma metastasis. It illustrates each lesion and diagnosis with digitally enhanced color photomicrographs and tables.
Àâòîð: Ryan J. Sullivan Íàçâàíèå: BRAF Targets in Melanoma ISBN: 1493921428 ISBN-13(EAN): 9781493921423 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 20962.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå: This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF inhibitors are effective for a short period of time, but there is little hope that this drugs as single agents will lead to durable benefit in a majority of patients. Among scientists and researchers who work in drug discovery, there is a lot of interest in the development of molecularly targeted cancer agents. Namely, the identification of a molecular target, the selection of molecules which effectively inhibit this target. What is starkly different about the development of this class of compounds, however, is that the mechanism of action of these agents are not as straightforward as was once previously assumed and the mechanisms of resistance that tumor cells employ to evade complete destruction are unlike any that have been described before. These discoveries in addition to utilization of modern molecular biology techniques have led to a series of hypotheses regarding which other types of molecules could be used in combination with BRAF-inhibitors in hopes of revolutionizing the potential of therapeutics in melanoma.
Îïèñàíèå: This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics.
Îïèñàíèå: Introducing metastatic melanomas, this book details diagnosis, clinical symptoms, types and AJCC staging, followed by a discussion of treatment problems and how immunotherapy provided the solution. The immune system, approved drugs and their molecular action are discussed, with the most promising candidates from ongoing clinical trials.
