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Intrinsically Disordered Proteins Studied by NMR Spectroscopy, Isabella C. Felli; Roberta Pierattelli


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Автор: Isabella C. Felli; Roberta Pierattelli
Название:  Intrinsically Disordered Proteins Studied by NMR Spectroscopy
ISBN: 9783319371177
Издательство: Springer
Классификация:




ISBN-10: 3319371177
Обложка/Формат: Paperback
Страницы: 421
Вес: 0.61 кг.
Дата издания: 29.10.2016
Серия: Advances in Experimental Medicine and Biology
Язык: English
Размер: 234 x 156 x 23
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

Nuclear Magnetic Resonance and Bioinformatics Studies on Intrinsically Disordered Proteins.- Structure and Dynamics of Intrinsically Disordered Proteins.- NMR methods for the study of IDP structure, dynamics and interactions: general overview and practical guidelines.- Ensemble Calculation for IDPs Using NMR Parameters.- NMR Spectroscopic Studies of the Conformational Ensembles of Intrinsically Disordered Proteins.- Recombinant IDPs for NMR: Tips and Tricks.- Biophysical Methods to Investigate Intrinsically Disordered Proteins: Avoiding an Elephant and Blind Men Situation.- Application of SAXS for the Structural Characterization of IDPs.- Bioinformatics Approaches for Predicting Disordered Protein Motifs.- Towards Understanding Protein Disorder In-Cell.- The Protein Ensemble Database.- Order and Disorder in the Replicative Complex of Paramyxoviruses.- Druggability of Intrinsically Disordered Proteins.- Beta Amyloid Hallmarks: From Intrinsically Disordered Proteins to Alzheimers Disease.




Modified Au-Based Nanomaterials Studied by Surface Plasmon Resonance Spectroscopy

Автор: A?da Serrano Rubio
Название: Modified Au-Based Nanomaterials Studied by Surface Plasmon Resonance Spectroscopy
ISBN: 3319370162 ISBN-13(EAN): 9783319370163
Издательство: Springer
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Цена: 13059.00 р.
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Описание: SPR spectroscopy is employed to study Au-based plasmonic nanostructures fabricated by novel methods, and a new experimental device is developed combining SPR with X-ray absorption spectroscopy at a synchrotron beamline.

Intrinsically Disordered Proteins Studied by NMR Spectroscopy

Автор: Isabella C. Felli; Roberta Pierattelli
Название: Intrinsically Disordered Proteins Studied by NMR Spectroscopy
ISBN: 3319201638 ISBN-13(EAN): 9783319201634
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrinsic protein disorder is now recognized as one of the key features for a large variety of cellular functions, where structural flexibility presents a functional advantage in terms of binding plasticity and promiscuity and this volume explores this exciting new research. Recent progress in the field has radically changed our perspective to study IDPs through NMR: increasingly complex IDPs can now be characterized, a wide range of observables can be determined reporting on the structural and dynamic properties, computational methods to describe the structure and dynamics are in continuous development and IDPs can be studied in environments as complex as whole cells. This volume communicates the new exciting possibilities offered by NMR and presents open questions to foster further developments. Intrinsically Disordered Proteins Studied by NMR Spectroscopy provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.

Intrinsically Disordered Proteins

Автор: Vladimir N. Uversky
Название: Intrinsically Disordered Proteins
ISBN: 331908920X ISBN-13(EAN): 9783319089201
Издательство: Springer
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Цена: 9141.00 р.
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Описание: In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs).

Intrinsically Disordered Protein Analysis

Автор: Vladimir N. Uversky; A. Keith Dunker
Название: Intrinsically Disordered Protein Analysis
ISBN: 1493962302 ISBN-13(EAN): 9781493962303
Издательство: Springer
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Цена: 23058.00 р.
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Описание: Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions. In Intrinsically Disordered Protein Analysis :Methods and Experimental Tools, expert researchers explore the high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases. Volume 1 includes sections on assessing IDPs in the living cell,NMR based techniques, vibrational spectroscopy, and other spectroscopic techniques. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Intrinsically Disordered Protein Analysis: Methods and Experimental Tools helps scientists further their investigations of these fascinating and dynamic molecules.

Intrinsically Disordered Protein Analysis

Автор: Vladimir N. Uversky; A. Keith Dunker
Название: Intrinsically Disordered Protein Analysis
ISBN: 1493944843 ISBN-13(EAN): 9781493944842
Издательство: Springer
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Цена: 20263.00 р.
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Описание: The second volume in the series on the experimental methods used to identify IDPs and analyze their structure, this publication includes reproducible protocols for single molecule techniques and methods to assess protein size and shape, among many others.

Modified Au-Based Nanomaterials Studied by Surface Plasmon Resonance Spectroscopy

Автор: A?da Serrano Rubio
Название: Modified Au-Based Nanomaterials Studied by Surface Plasmon Resonance Spectroscopy
ISBN: 3319194011 ISBN-13(EAN): 9783319194011
Издательство: Springer
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Цена: 15672.00 р.
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Описание: SPR spectroscopy is employed to study Au-based plasmonic nanostructures fabricated by novel methods, and a new experimental device is developed combining SPR with X-ray absorption spectroscopy at a synchrotron beamline.

Physics of Structurally Disordered Solids

Автор: Shashanka Mitra
Название: Physics of Structurally Disordered Solids
ISBN: 1468408526 ISBN-13(EAN): 9781468408522
Издательство: Springer
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Цена: 6986.00 р.
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Описание: It is generally believed that the amorphous state is a metastable one with respect to the crystal- line ordered state, and the conversion to the crystal- line state may or may not be easy depending on the na- ture of the material, e.

Time-Dependent Effects in Disordered Materials

Автор: Roger Pynn
Название: Time-Dependent Effects in Disordered Materials
ISBN: 1468474782 ISBN-13(EAN): 9781468474787
Издательство: Springer
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Цена: 12157.00 р.
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Описание: This volume comprised the proceedings of a NATO Advanced Study Institute held in Geilo, Norway between 29 March and 9 April 1987.

Physics of Disordered Materials

Автор: David Adler
Название: Physics of Disordered Materials
ISBN: 146129519X ISBN-13(EAN): 9781461295198
Издательство: Springer
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Цена: 16979.00 р.
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Описание: This volume and its two companion volumes, entitled Tetrahedrally-Bonded Amorphous Semiconductors and Localization and Metal-Insulator Transitions, are our way of paying special tribute to Sir Nevill Mott and to express our heartfelt wishes to him on the occasion of his eightieth birthday.

Disordered Semiconductors

Автор: Marc A. Kastner; Stadford R. Ovshinsky; Gordon A.
Название: Disordered Semiconductors
ISBN: 1461290287 ISBN-13(EAN): 9781461290285
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Twenty-four years ago, Hellmut Fritzsche came to our laboratory to evaluate our work in amorphous materials.

Atomic Diffusion in Glasses Studied with Coherent X-Rays

Автор: Manuel Ross
Название: Atomic Diffusion in Glasses Studied with Coherent X-Rays
ISBN: 3319286447 ISBN-13(EAN): 9783319286440
Издательство: Springer
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Цена: 14365.00 р.
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Описание: Introduction.- Theory.- Experimental.- Data Analysis.- Proof of Concept: Direct Observation of Atomic Diffusion in Glasses.- Practical Application: Tailoring Fast Ionic Diffusion.- Conclusion.


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