Insulin-like Growth Factor Receptor Signalling, Derek Leroith; Walter Zumkeller; Robert C. Baxter

Автор: Maria P. Abracchio; Michael Williams
Название: Purinergic and Pyrimidinergic Signalling II
ISBN: 3642632238 ISBN-13(EAN): 9783642632235
Издательство: Springer
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Цена: 39130.00 р.
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Описание: With contributions by numerous experts

Автор: Maria P. Abracchio; Michael Williams
Название: Purinergic and Pyrimidinergic Signalling
ISBN: 3642087426 ISBN-13(EAN): 9783642087424
Издательство: Springer
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Цена: 62888.00 р.
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Описание: With contributions by numerous experts

Автор: Isabel Varela-Nieto; Julie Ann Chowen
Название: The Growth Hormone/Insulin-Like Growth Factor Axis during Development
ISBN: 1461498112 ISBN-13(EAN): 9781461498117
Издательство: Springer
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Цена: 30745.00 р.
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Описание: Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.

Автор: Jordan V Craig
Название: Estrogen Action, Selective Estrogen Receptor Modulators and
ISBN: 1848169574 ISBN-13(EAN): 9781848169579
Издательство: World Scientific Publishing
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Цена: 26928.00 р.
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Описание: Presents the evolution of the authors` ideas about estrogen action and its modulation by a fresh group of drugs called SERMs (Selective Estrogen Receptor Modulators). This title presents a journey over years of discovery and success in advancing women`s health, with the prospect of improved medicinal chemistry for the future.

Автор: A. Cato; H. Schaecke; K. Asadullah
Название: Recent Advances in Glucocorticoid Receptor Action
ISBN: 3662046628 ISBN-13(EAN): 9783662046623
Издательство: Springer
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Цена: 26122.00 р.
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Автор: Antonio Cano; Joacquim Calaf i Alsina; Jose Luis D
Название: Selective Estrogen Receptor Modulators
ISBN: 3642445527 ISBN-13(EAN): 9783642445521
Издательство: Springer
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Цена: 19564.00 р.
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Описание: The increasing awareness on the varied consequences of hypogonadism in distinct organs and systems has supported the notion of estrogens as systemic agents. This observation is congruent with the variety of tissues affected by - trogens when used in hormone therapy formulations on hypogonadic women. Apart from the genital tract and the breast, recognized as traditional targets for estrogens, the skeleton, the vascular tree, or the central nervous system, are good examples of territories that have demonstrated sensitivity to estrogens. This evidence has created great interest, as shown by the great amount of lit- ature that has been produced on the bene?ts and risks associated with the use of estrogens. In parallel to the clinical interest, basic research has improved our kno- edge on the complexities involved in estrogen action at the molecular level. Together with effects mediated through speci?c receptors, a concept that has been the mainstay of the interpretation of estrogen action for years, there is enough evidence to hold the notion of receptor-independent effects. The substantial advances in modern technology applied to research have helped in enlightening the particulars of this versatile action of estrogens. This more detailed knowledge on the sophisticated mechanism of action of estrogens has nourished the emergence of multiple hypotheses speculating with the p- sibility of manipulating estrogen action. The notion that a widely extended regulatory system of cell function, as it is the estrogen receptor machinery, might be modulated at wish has arisen as an attractive, although still elusive postulate.

Автор: Gerald Litwack
Название: Receptor Purification
ISBN: 1461267714 ISBN-13(EAN): 9781461267713
Издательство: Springer
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Цена: 20962.00 р.
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Автор: Gerald Litwack
Название: Receptor Purification
ISBN: 146126779X ISBN-13(EAN): 9781461267799
Издательство: Springer
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Цена: 20962.00 р.
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Автор: Andrea Manni; Michael Verderame
Название: Selective Estrogen Receptor Modulators
ISBN: 1468496654 ISBN-13(EAN): 9781468496659
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs.

Автор: Evanthia Diamanti-Kandarakis; John E. Nestler; Dim
Название: Insulin Resistance and Polycystic Ovarian Syndrome
ISBN: 1617377635 ISBN-13(EAN): 9781617377631
Издательство: Springer
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Цена: 34799.00 р.
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Описание: Polycystic Ovarian Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. Providing a state-of-the-art analysis of the connection between insulin resistance and PCOS, this book comprehensively covers a range of topics.