The Blood-Brain Barrier, Amino Acids and Peptides, M. Segal; Berislav V. Zlokovic
Автор: M. Segal; Berislav V. Zlokovic Название: The Blood-Brain Barrier, Amino Acids and Peptides ISBN: 940107500X ISBN-13(EAN): 9789401075008 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Definition of the barrier The interstitial fluid (rSF) of the brain is separated from the blood by the blood-brain barrier (BBB). This barrier must not be thought of as a single entity or as an absolute restriction to all molecules, but as a multiple structure located at several sites within the brain.
Автор: Barnes Название: Brain-gut Peptides and Reproductive Function ISBN: 0849388481 ISBN-13(EAN): 9780849388484 Издательство: Taylor&Francis Рейтинг: Цена: 33686.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book elucidates the role of brain-gut peptides in neuroendocrine regulation for understanding how these peptides interact with the reproductive neuroendocrine axis and for developing novel therapeutic agents for fertility or contraceptive therapies.
Автор: K.O. Stumpe; Karin Kraft; Alan I. Faden Название: Opioid Peptides and Blood Pressure Control ISBN: 3540189351 ISBN-13(EAN): 9783540189350 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A. , FADEN, K. KRAFr, and K. O. STUMPE Following the discovery of the pentapeptide enkephalins in 1975, a number of endogenous opioid peptides and opiate receptors have been identified. Endogenous opioids and opiate-receptor mechanisms have been implicated in a variety of regulat- ory and dysregulatory functions including analgesia, cardiovascular regulation, shock, hypertension, traumatic spinal cord and brain injury, stroke, immune func- tion, feeding behavior, diuresis, gastrointestinal motility, and respiratory control, among others. Over the past 10 years, many studies have demonstrated a relationship between endogenous opioids and the cardiovascular system under both homeostatic and pathophysiological conditions. Opioids and opiate receptors have been found in various cardioregulatory sites within the brain and spinal cord, as well as in peripheral tissues such as sympathetic ganglia, adrenal gland, and heart. Both endogenous opioids and exogenous opiates have been shown to produce potent cardiovascular effects following central nervous system or systemic administration. Opiate-receptor antagonists have been demonstrated to reverse hypotension from sepsis, hypo- volemia, and anaphylaxis; such studies have been used to infer activity of endogenous opioid systems in shock. Changes in tissue concentrations of endogenous opioids and or opiate receptors have been found after shock and hypertension, further implying a role for opioid systems in the etiology of these conditions. In addition, modification of opiate receptor regulation, receptor binding, or opioid metabolism has also been used to establish a potential role for endogenous opioid systems in cardiovascular control and dyscontrol.
Описание: This volume is a collection of a variety of brain proteins and peptides whose structures and functions are relatively well known. The volume explores the progress that has been made in the field over the past few years and provides insight into the field today.
Автор: Franco Fraschini; Russel J. Reiter Название: Role of Melatonin and Pineal Peptides in Neuroimmunomodulation ISBN: 1461366739 ISBN-13(EAN): 9781461366737 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ARW held in Erice, Sicily, Italy, June 3-9, 1990
Автор: E.A. Neuwelt Название: Implications of the Blood-Brain Barrier and Its Manipulation ISBN: 1461280397 ISBN-13(EAN): 9781461280392 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Finally, the 1967 paper by Reese and Kamovsky, 11 entitled "Fine structural localization of a blood-brain barrier to exogenous peroxidase," sited the barrier at the continuous layer of cerebrovascular endothelial cells, which are connected by tight junctions.
Автор: E.A. Neuwelt Название: Implications of the Blood-Brain Barrier and Its Manipulation ISBN: 1461572576 ISBN-13(EAN): 9781461572572 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Future brain treatments with regulatory peptides, immune mediators, and gene components will require selective methods to deliver these agents to specific brain regions.
Автор: Harold Gainer Название: Peptides in Neurobiology ISBN: 1461341329 ISBN-13(EAN): 9781461341321 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Elucidation of the important roles played by peptides as hypothalamic-adenohypo- physeal releasing factors, or regulatory hormones, has in recent years led to the recognition that peptides may also be of significance as intercellular messengers in other regions of the nervous system. In this regard, it is interesting that Sub- stance P, which has been proposed as a putative neurotransmitter in the spinal cord, was rediscovered by Leeman and her co-workers during their search for the corticotropin-releasing factor in the hypothalamus. Indeed, with the wide- spread availability and use of radioimmunoassay techniques, it has become ap- parent that various "hypothalamic releasing factors" are localized in extrahypo- thalamic areas of the central nervous system as well. This book represents an expression of the belief that the impact on neurobiology of research into neuro- peptides will be comparable to, if not greater than, the recent achievements obtained with the biogenic amines. As already appears to be the case, future inves- tigations on brain pep tides will undoubtedly uncover a host of new transmitter candidates, with obvious implications for neuropharmacology. Perhaps the most dramatic developments in this field have been the discoveries of the endogenous opiate peptides (enkephalin and endorphin), and the profound physiological and behavioral effects of specific peptides.
Автор: Xiao-Yu Hu; Rui Wang; James P. Tam Название: Peptides ISBN: 9401738750 ISBN-13(EAN): 9789401738750 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 5th International Chinese Peptide Symposium 1998
Автор: Luis Olivares-Quiroz; Orlando Guzm?n-L?pez; Hector Название: Physical Biology of Proteins and Peptides ISBN: 331937284X ISBN-13(EAN): 9783319372846 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Chapter 1 The structural determinants of the immunoglobulin light chain amyloid aggregation.- Chapter 2 Thermodynamics and kinetics of amyloid aggregation from atomistic simulations.- Chapter 3 Determination of the size of the primary and secondary folding nuclei of protofibrils from the concentration dependence of the rate and the lag-time of their formation.- Chapter 4 Modulation of cholera toxin structure/function by Hsp90.- Chapter 5 Function, structure and stability of human gamma D crystallins: A review.- Chapter 6 Protein motions, dynamic effects and thermal stability in dihydrofolate reductase from the hyperthermophile Thermotoga maritime.- Chapter 7 Ab initio folding of glycophorin A and acetylcholine M2 transmembrane segments via simplified environment molecular simulations.- Chapter 8 Multi-scale approaches to dynamical transmission of protein allostery.- Chapter 9 Dynamics of membrane proteins and lipid bilayers.- Chapter 10 What makes a transcriptional master regulator? A systems biology approach.
Автор: David Kobiler; Shlomo Lustig; Shlomo Shapira Название: Blood-Brain Barrier ISBN: 1461351413 ISBN-13(EAN): 9781461351412 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 44th OHOLO Conference on Blood-Brain Barrier: Drug Delivery and Brain Pathology, held September 10-14, 2000, Dead Sea, Israel
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