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Opioid Peptides and Blood Pressure Control, K.O. Stumpe; Karin Kraft; Alan I. Faden


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Автор: K.O. Stumpe; Karin Kraft; Alan I. Faden
Название:  Opioid Peptides and Blood Pressure Control
ISBN: 9783540189350
Издательство: Springer
Классификация:




ISBN-10: 3540189351
Обложка/Формат: Paperback
Страницы: 300
Вес: 0.50 кг.
Дата издания: 22.06.1988
Язык: English
Размер: 244 x 170 x 17
Основная тема: Biomedicine
Подзаголовок: 11th Scientific Meeting of the International Society of Hypertension Satellite Symposium · Bonn · September 6–7, 1986
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: A. , FADEN, K. KRAFr, and K. O. STUMPE Following the discovery of the pentapeptide enkephalins in 1975, a number of endogenous opioid peptides and opiate receptors have been identified. Endogenous opioids and opiate-receptor mechanisms have been implicated in a variety of regulat- ory and dysregulatory functions including analgesia, cardiovascular regulation, shock, hypertension, traumatic spinal cord and brain injury, stroke, immune func- tion, feeding behavior, diuresis, gastrointestinal motility, and respiratory control, among others. Over the past 10 years, many studies have demonstrated a relationship between endogenous opioids and the cardiovascular system under both homeostatic and pathophysiological conditions. Opioids and opiate receptors have been found in various cardioregulatory sites within the brain and spinal cord, as well as in peripheral tissues such as sympathetic ganglia, adrenal gland, and heart. Both endogenous opioids and exogenous opiates have been shown to produce potent cardiovascular effects following central nervous system or systemic administration. Opiate-receptor antagonists have been demonstrated to reverse hypotension from sepsis, hypo- volemia, and anaphylaxis; such studies have been used to infer activity of endogenous opioid systems in shock. Changes in tissue concentrations of endogenous opioids and or opiate receptors have been found after shock and hypertension, further implying a role for opioid systems in the etiology of these conditions. In addition, modification of opiate receptor regulation, receptor binding, or opioid metabolism has also been used to establish a potential role for endogenous opioid systems in cardiovascular control and dyscontrol.


Opioid Therapy in the 21st Century

Автор: Smith Howard S.
Название: Opioid Therapy in the 21st Century
ISBN: 0199844976 ISBN-13(EAN): 9780199844975
Издательство: Oxford Academ
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Цена: 7522.00 р.
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Описание: Opioid Therapy in the 21st Century, Second Edition provides clinicians with up-to-date, evidence-based information about appropriate opioid use, including the potential benefits and adverse affects of the therapy.

Opioid Receptors

Автор: Santi M. Spampinato
Название: Opioid Receptors
ISBN: 1493917072 ISBN-13(EAN): 9781493917075
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Opioid Receptors: Methods and Protocols serves as a comprehensive guide to both key new techniques and established methods for the investigation of genetics, structural biology, transcription, and post-transcriptional events of opioid receptors.

Expert Decision Making on Opioid Treatment

Автор: Ballantyne, Jane; Tauben, David J.
Название: Expert Decision Making on Opioid Treatment
ISBN: 0199768889 ISBN-13(EAN): 9780199768882
Издательство: Oxford Academ
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Цена: 9662.00 р.
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Описание: This book offers expert, balanced, concise guidance on how clinicians can navigate a number of complex considerations to formulate a treatment plan for chronic pain that either includes or advisedly excludes opioids.

Neural Functions of the Delta-Opioid Receptor

Автор: Ying Xia
Название: Neural Functions of the Delta-Opioid Receptor
ISBN: 3319254936 ISBN-13(EAN): 9783319254937
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This book is the first to summarize the progress of research on neural functions of the the delta opioid receptor (DOR) to date. The book will provide a comprehensive overview of the current state of DOR research and provide a blueprint for future directions.ГЇВїВЅ

Opioid Analgesics

Автор: A.F. Casy; R.T. Parfitt
Название: Opioid Analgesics
ISBN: 1489905871 ISBN-13(EAN): 9781489905871
Издательство: Springer
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Цена: 27950.00 р.
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Описание: The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal­ gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono­ logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability.

Opioid Receptors

Автор: Santi M. Spampinato
Название: Opioid Receptors
ISBN: 1493955500 ISBN-13(EAN): 9781493955503
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Opioid Receptors: Methods and Protocols serves as a comprehensive guide to both key new techniques and established methods for the investigation of genetics, structural biology, transcription, and post-transcriptional events of opioid receptors. Other methods cover the cellular detection and trafficking of opioid receptors in vitro and in vivo. Procedures aimed to investigate signaling pathways modulated by opioid receptors and model systems to study opioid receptor-mediated functions are also included. Finally, methods to assay behavioral effects mediated by opioid receptors are described. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective introductions, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Wide-ranging and authoritative, Opioid Receptors: Methods and Protocols will help both experienced and new entrants in this field to carry out their experiments successfully and with new inspiration.

Opioid Analgesics

Автор: A.F. Casy; R.T. Parfitt
Название: Opioid Analgesics
ISBN: 0306421305 ISBN-13(EAN): 9780306421303
Издательство: Springer
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Цена: 36570.00 р.
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Описание: The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal- gesics particularly relevant and timely.

Treating Comorbid Opioid Use Disorder in Chronic Pain

Автор: Annette M. Matthews; Jonathan C. Fellers
Название: Treating Comorbid Opioid Use Disorder in Chronic Pain
ISBN: 3319298615 ISBN-13(EAN): 9783319298610
Издательство: Springer
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Цена: 12577.00 р.
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Описание: ГЇВїВЅ This in-depth text addresseshow to approach and treat the chronic pain patient struggling with problematicopioid use. The last part of the book addressestreating comorbid pain and opioid use disorder in different medical settings and thetreatment of co-occurring mental illnesses and substance abuse.

Brain-gut Peptides and Reproductive Function

Автор: Barnes
Название: Brain-gut Peptides and Reproductive Function
ISBN: 0849388481 ISBN-13(EAN): 9780849388484
Издательство: Taylor&Francis
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Цена: 33686.00 р.
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Описание: This book elucidates the role of brain-gut peptides in neuroendocrine regulation for understanding how these peptides interact with the reproductive neuroendocrine axis and for developing novel therapeutic agents for fertility or contraceptive therapies.

Centrally Acting Peptides

Автор: John Hughes
Название: Centrally Acting Peptides
ISBN: 1349036706 ISBN-13(EAN): 9781349036707
Издательство: Springer
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Цена: 6986.00 р.
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The Blood-Brain Barrier, Amino Acids and Peptides

Автор: M. Segal; Berislav V. Zlokovic
Название: The Blood-Brain Barrier, Amino Acids and Peptides
ISBN: 0746201222 ISBN-13(EAN): 9780746201220
Издательство: Springer
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Цена: 28734.00 р.
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Описание: Definition of the barrier The interstitial fluid (rSF) of the brain is separated from the blood by the blood-brain barrier (BBB). This barrier must not be thought of as a single entity or as an absolute restriction to all molecules, but as a multiple structure located at several sites within the brain.

The Blood-Brain Barrier, Amino Acids and Peptides

Автор: M. Segal; Berislav V. Zlokovic
Название: The Blood-Brain Barrier, Amino Acids and Peptides
ISBN: 940107500X ISBN-13(EAN): 9789401075008
Издательство: Springer
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Цена: 22201.00 р.
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Описание: Definition of the barrier The interstitial fluid (rSF) of the brain is separated from the blood by the blood-brain barrier (BBB). This barrier must not be thought of as a single entity or as an absolute restriction to all molecules, but as a multiple structure located at several sites within the brain.


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