Автор: Ballanyi Название: Isolated Central Nervous System Circuits ISBN: 1627030190 ISBN-13(EAN): 9781627030199 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Advances in methodologies and experimental models are pivotal to furthering our understanding of central nervous system (CNS) functions in mammals. Isolated Central Nervous System Circuits examines the application a variety of technologies to mostly active in vitro preparations from basically different CNS regions with a diversity of functions. From patch-clamp, multiphoton imaging, live fluorescent protein expression, or immunohistochemistry techniques to acute or 'organotypic' slices and en bloc preparations, this detailed volume features key protocols and examples for exciting results from the labs of renowned experts. Written for the popular Neuromethods series, chapters include the kind of thorough implementation advice that is vital for achieving successful results. Comprehensive and cutting-edge, Isolated Central Nervous System Circuits will greatly aid scientists to further improve models and to develop corresponding models of not yet intensively studied structures such as nucleus ruber, superior colliculus, or basal ganglia.
Автор: David R. Brown; A. Alemayehu; B. Amiranoff; D.L. B Название: Gastrointestinal Regulatory Peptides ISBN: 364277816X ISBN-13(EAN): 9783642778162 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Authored by an array of internationally distinguished scientists, it deals with issues of peptide localization and biosynthesis in gastrointestinal cells, mechanisms of peptide release and inactivation and the nature of peptide receptors.
Автор: Martin C. Michel Название: Neuropeptide Y and Related Peptides ISBN: 3642622828 ISBN-13(EAN): 9783642622823 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: with contributions by numerous experts
Автор: Johann C. R?egg Название: Peptides as Probes in Muscle Research ISBN: 3642764118 ISBN-13(EAN): 9783642764110 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein-protein interactions are involved in muscle contraction and signal transduction. These timely contributions by several experts will appeal to the researchers in muscle physiology, cardiovascular pharmacology and cell biology who are interested in this new approach.
Автор: K.O. Stumpe; Karin Kraft; Alan I. Faden Название: Opioid Peptides and Blood Pressure Control ISBN: 3540189351 ISBN-13(EAN): 9783540189350 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A. , FADEN, K. KRAFr, and K. O. STUMPE Following the discovery of the pentapeptide enkephalins in 1975, a number of endogenous opioid peptides and opiate receptors have been identified. Endogenous opioids and opiate-receptor mechanisms have been implicated in a variety of regulat- ory and dysregulatory functions including analgesia, cardiovascular regulation, shock, hypertension, traumatic spinal cord and brain injury, stroke, immune func- tion, feeding behavior, diuresis, gastrointestinal motility, and respiratory control, among others. Over the past 10 years, many studies have demonstrated a relationship between endogenous opioids and the cardiovascular system under both homeostatic and pathophysiological conditions. Opioids and opiate receptors have been found in various cardioregulatory sites within the brain and spinal cord, as well as in peripheral tissues such as sympathetic ganglia, adrenal gland, and heart. Both endogenous opioids and exogenous opiates have been shown to produce potent cardiovascular effects following central nervous system or systemic administration. Opiate-receptor antagonists have been demonstrated to reverse hypotension from sepsis, hypo- volemia, and anaphylaxis; such studies have been used to infer activity of endogenous opioid systems in shock. Changes in tissue concentrations of endogenous opioids and or opiate receptors have been found after shock and hypertension, further implying a role for opioid systems in the etiology of these conditions. In addition, modification of opiate receptor regulation, receptor binding, or opioid metabolism has also been used to establish a potential role for endogenous opioid systems in cardiovascular control and dyscontrol.
Автор: Brodal Название: The Central Nervous System.2003 ISBN: 0195165608 ISBN-13(EAN): 9780195165609 Издательство: Oxford Academ Цена: 8712.00 р. Наличие на складе: Поставка под заказ.
Описание: A major goal of this well-established textbook is to provide knowledge and understanding of neuroscience as a basis for clinical thinking. The strong emphasis on linking basic sciences with their clinical application has implications for the choices of which topics to treat in depth and which to treat more summarily - making this different from most other neuroscience textbooks. For example, topics of great practical importance like the cranial nerves, the autonomic nervous system, and pain are treated in depth.
Автор: Dietmar Richter Название: Regulatory Peptides and Cognate Receptors ISBN: 3662129086 ISBN-13(EAN): 9783662129081 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix "neuro". Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a family of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g. CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as "reverse physiology" to uncover new peptides and orphan receptors.
Автор: J. Cheronis; Repine Название: Proteases, Protease Inhibitors and Protease-Derived Peptides ISBN: 3034873999 ISBN-13(EAN): 9783034873994 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Klaus Ballanyi Название: Isolated Central Nervous System Circuits ISBN: 1493961837 ISBN-13(EAN): 9781493961832 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Neuromethods series volume offers protocols and examples for exciting results from the labs of renowned experts. Covers patch-clamp, multiphoton imaging, live fluorescent protein expression, immunohistochemistry techniques, `organotypic` slices and more.
Описание: The present volume covers the physiology of the visual system beyond the optic nerve. These investigations began in the periphery: HARTLINE`S pioneering experiments on single visual elements of Limulus in 1932 started a successful period of neuronal recordings which ascended from the retina to the highest centres in the visual brain.
Описание: Over the past decade, the study of microglial cells has gained increasing importance, in particular for those working in the fields of degeneration and regeneration. Microglia in the Regenerating and Degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, currently the most widely studied disorder of the central nervous system. In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the vitally important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and also reviews microglial cell function and physiology. Cellular neurobiologists will find that this is a valuable guide to the importance and role of microglia in the CNS.
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