Описание: Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease.
Автор: Yehuda Shoenfeld,Nancy Agmon–Levin Название: Vaccines and Autoimmunity ISBN: 1118663438 ISBN-13(EAN): 9781118663431 Издательство: Wiley Рейтинг: Цена: 22485.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.
Автор: C. Jane Welsh; Mary Meagher; Esther Sternberg Название: Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity ISBN: 1489997237 ISBN-13(EAN): 9781489997234 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a lucid summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense.
Описание: Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to "molecules and cells that negatively regulate T-cell activation".
Описание: In a fully revised second edition, this comprehensive review of clinical and experimental aspects of IL-17 and IL-22 and the cells that produce them covers the latest scientific advances, with additional chapters on processes such as receptor family signaling.
Автор: Andreas Radbruch; Peter E. Lipsky Название: Current Concepts in Autoimmunity and Chronic Inflammation ISBN: 364206745X ISBN-13(EAN): 9783642067457 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions.
Описание: Explains how immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none manner. This book also explains why vaccines fail.
Автор: A.G. Dalgleish; A. Albertini; Rodolfo Paoletti Название: The Impact of Biotechnology on Autoimmunity ISBN: 9401044848 ISBN-13(EAN): 9789401044844 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The association with infectious diseases and autoimmunity is comprehensively covered by David Isenberg who reviews major issues, such as the association of autoantibodies appearing after infectious disease and antibacterial antibodies associated with autoimmune disease.
Автор: Moncef Zouali Название: Molecular Autoimmunity ISBN: 1461498945 ISBN-13(EAN): 9781461498940 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: - Preface -Contributors -Innate Immunity in Experimental Autoimmune Myocarditis -Toll-Like Receptor 9 and Autoimmunity -C-Reactive Protein as a Regulator of Autoimmune Disease -NKT Cells and Autoimmune Type 1 Diabetes -The Genetics of Human Autoimmune Diseases -Failure to Maintain T cell DNA Methylation and Chromatin Structure Contributes to Human Lupus -Complement Components C4A and C4B in Human Lupus -Non-MHC Genetic Polymorphisms with Functional Importance for Human Myasthenia Gravis -Rheumatic Heart Disease: Molecular Basis of Autoimmune Reactions Leading to Valvular Lesions -Autoimmunity Against Desmogleins in Pemphigus Vulgaris -The Molecular Basis of Celiac Disease -Intrathymic Expression of Neuromuscular Acetylcholine Receptors and the Immunopathogenesis of Myasthenia Gravis -Autoantiboties and Nephritis: Different Roads May Lead to Rome -Estrogen, Interferon-gamma, and Lupus -Extent of Regulatory T cell Influence on Major Histocompatibility Complex Class II Gene Control of Susceptibility in Murine Autoimmune Thyroiditis -The Role of Autoimmunity in Multiple Sclerosis -Crippled B Lymphocyte Signaling Checkpoints in Systemic Autoimmunity -Disrupted T cell Receptor Signaling Pathways in Systemic Autoimmunity -Immune cell Signaling and Gene Transcription in Human Systemic Lupus Erythematosus -Accumulation of Self-Antigens in Systemic Lupus Erythematosus -B Lymphocyte Depletion Therapy in Autoimmune Disorders: Chasing Trojan Horse? -B Lymphocyte Stimulator (BLyS) and Autoimmune Rheumatic Diseases -Control and Induction of Autoimmunity by Cytokine and Anti-Cytokine Treatments -Hematopoietic Stem Cell Transplantation for the Treatment of Severe Autoimmune Diseases -Molecular Mimicry in Autoimmune Uveitis: From Pathogenesis to Therapy -Molecular Pathogenesis of the Antiphospholipid Syndrome: Towards Novel Therapeutic Targets -A Novel Approach to the Prevention of Atherosclerosis -Antigen-SpecificRegulation of Autoimmunity -Index
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