Prolactin, Nelson D. Horseman

Автор: Horst-Dieter Dellmann
Название: Comparative Endocrinology of Prolactin
ISBN: 1461566770 ISBN-13(EAN): 9781461566779
Издательство: Springer
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Описание: The selection of prolactin as the subject of the Midwest Con- ference on Endocrinology was not only dictated by the recent ad- vances in prolactin research but also by the long tradition in that particular area of Endocrinology in the laboratory of C.W.

Автор: E. Fl?ckiger; E. DelPozo; K. v. Werder
Название: Prolactin
ISBN: 3642817238 ISBN-13(EAN): 9783642817236
Издательство: Springer
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Описание: This can partly be explained by the fact that human growth hormone isolated in 1961, is itself a potent lactogen, in contrast to nonprimate growth hormones, and is present in the normal human pituitary in much greater amounts than prolactin.

Автор: Maria Diakonova, PhD
Название: Recent Advances in Prolactin Research
ISBN: 3319352768 ISBN-13(EAN): 9783319352763
Издательство: Springer
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Описание: Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors.

Автор: Maria Diakonova, PhD
Название: Recent Advances in Prolactin Research
ISBN: 3319121138 ISBN-13(EAN): 9783319121130
Издательство: Springer
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Описание: Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged.

Автор: Nelson D. Horseman
Название: Prolactin
ISBN: 1461356768 ISBN-13(EAN): 9781461356769
Издательство: Springer
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Описание: Be- cause of the historical and practical importance of knowledge regarding the hypothala- mus-Iactotroph axis, the first chapters of this volume are dedicated to reviewing the physiology, development, and cell biology of lactotroph regulation.