Brain Tumor Immunotherapy, Linda M. Liau; Donald P. Becker; Timothy F. Clough
Автор: Yotnda Название: Immunotherapy of Cancer ISBN: 1607617854 ISBN-13(EAN): 9781607617853 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. It includes coverage of pre-clinical models for cancer immunotherapy.
Автор: Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642141358 ISBN-13(EAN): 9783642141355 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Автор: George C. Prendergast Название: Cancer Immunotherapy, ISBN: 0123942969 ISBN-13(EAN): 9780123942968 Издательство: Elsevier Science Рейтинг: Цена: 16169.00 р. Наличие на складе: Поставка под заказ.
Описание: There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles.
Автор: Rees Robert C. Название: Tumor Immunology and Immunotherapy ISBN: 0199676860 ISBN-13(EAN): 9780199676866 Издательство: Oxford Academ Рейтинг: Цена: 36036.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Автор: Joseph D. Rosenblatt; Eckhard R. Podack; Glen N. B Название: Advances in Tumor Immunology and Immunotherapy ISBN: 1461488087 ISBN-13(EAN): 9781461488088 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines evolving paradigms in antigen presentation, dendritic cell biology, innate response and immunosuppressive mechanisms and strategies for manipulation of the immune system to treat neuroblastoma, leukemia, melanoma, lung cancer and more.
Название: Immunotherapy of cancer ISBN: 4431550305 ISBN-13(EAN): 9784431550303 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments of surgery, chemotherapy, and radiotherapy. The progress in fundamental understanding of tumor immunology and the recent advances in clinical trials have opened new avenues with a cancer vaccine in 2010 and immunocheckpoint modulation in 2011, with their approval already granted in the United States. Today, there are no doubts, even among experts in cancer chemotherapy and radiotherapy, that the immune system plays a vital role in tumor eradication. Following American approval, many clinical trials of cancer immunotherapy are being conducted. With this book the reader will readily understand the paradigm shift in cancer treatment and will realize the importance of cancer immunotherapy. The great value of immunotherapy will be obvious, not only for tumor shrinkage but for prolonging patient survival.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Автор: Xiang-Yang Wang Название: Immunotherapy of Cancer,128 ISBN: 0128023163 ISBN-13(EAN): 9780128023167 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology.
Автор: Sampson, John H. Название: Translational Immunotherapy of Brain Tumors ISBN: 0128024208 ISBN-13(EAN): 9780128024201 Издательство: Elsevier Science Рейтинг: Цена: 15917.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Besides the Privacy & Data Protection Foundation Courseware - English (ISBN: 9789401803595) publication you are advised to obtain the publication EU GDPR, A pocket guide (ISBN: 978 1 849 2855 5).Privacy & Data Protection Foundation covers the main subjects related to the protection of personal data. Candidates benefit from a certification that is designed to impart all the required knowledge to help ensure compliancy to the General Data Protection Regulation.Within the European Union regulations and standards regarding the protection of data are stringent. The General Data Protection Regulation (GDPR) went into force in May 2016 and organizations have until May 2018 to change their policies and processes to ensure they fully comply. Companies outside Europe will also need to comply when doing business in Europe. One of the solutions to comply in time is to qualify staff. Having certified professionals with the right level of knowledge can help prepare your organization to face these opportunities. The EXIN Privacy & Data Protection program covers the required knowledge of legislation and regulations relating to data protection and how this knowledge should be used to be compliant.
Автор: Howard L. Kaufman; Jedd D. Wolchok Название: General Principles of Tumor Immunotherapy ISBN: 9400787146 ISBN-13(EAN): 9789400787148 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book brings together the world`s leading authorities on tumor immunology. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated.
Автор: David W. Weiss Название: Tumor Antigenicity and Approaches to Tumor Immunotherapy ISBN: 3642674992 ISBN-13(EAN): 9783642674990 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The references brought in support of a given point are often intentionally varied,including both reports of original work and reviews, very recent observa- tions and contributions that gave initial impetus to investigations, in an attempt to exemplify the pertinent literature;
Автор: Zhang Название: Progress in Cancer Immunotherapy ISBN: 9401775532 ISBN-13(EAN): 9789401775533 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thisbook provides readers an extensive overview of recent progress in basicand clinical research on cancer immunotherapy. Thanks to rapid advances inmolecular biology and immunology, it has become increasingly evident thatcancer growth is influenced by host immune responses. With the success of anumber of clinical trials, immunotherapy has become a promising treatmentmodality of cancer. This book covers five major topics, including monoclonalantibodies, biological response modifiers, cancer vaccines, adoptive cellulartherapy and oncolytic viruses. It also examines the combination of differentimmune strategies as well as the combination of immunotherapy with othertreatments to increase anti-tumor effects. Throughthecomprehensive discussion of the topic, the book sheds valuable new light on thetreatment of tumors.
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