Treatment of Asthma: The long-acting beta-2-agonists, Friedrich Kummer

Автор: Freye Enno
Название: Opioids in Medicine / A systematic and comprehensive review of agonists, partial agonists, agonists/antagonists and antagonist in pain therapy
ISBN: 1402059469 ISBN-13(EAN): 9781402059469
Издательство: Springer
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Цена: 33401.00 р.
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Описание: This book fills the void to provide a comprehensive review of the theoretical knowledge and scope of opioid pharmacotherapy in pain medicine.

Автор: George Poste; Stanley T. Crooke
Название: Dopamine Receptor Agonists
ISBN: 1475703120 ISBN-13(EAN): 9781475703122
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Dopamine, in addition to its importance as a precursor of norepinephrine, is now known to be an important neurotransmitter in regulating functional activities in a number of major organ systems, including the central ner- vous system.

Автор: Bimal K. Banik
Название: Beta-Lactams
ISBN: 3319556207 ISBN-13(EAN): 9783319556208
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds.

Автор: A. Fleckenstein; C. Van Breemen; R. Gro?; F. Hoffm
Название: Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists
ISBN: 3642705014 ISBN-13(EAN): 9783642705014
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Held at Boppard, Germany, October 3-6, 1984

Автор: John P. Perkins
Название: The Beta-Adrenergic Receptors
ISBN: 1461267722 ISBN-13(EAN): 9781461267720
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Prior to 1974, the adrenergic receptors were known only in- directly as entities that responded to drugs in a selective manner to mediate a variety of physiologically important responses. During the intervening years, our view of adrenergic receptors has changed dramatically. The availability of high affinity 125I-labeled radioligands selective for these receptors presaged an explosion of experimenta- tion utilizing direct binding assays to establish the biochemical properties of the receptor protein. In the opening chapter, Stadel and Lefkowitz describe this development and its impact on our under- standing of the molecular basis of adrenergic receptor function. The availability of well-characterized receptor ligands, coupled with the development of efficient methods for detergent solubilization, formed the basis of receptor purification using affinity chromatography. The related technique of photoaffinity labeling provided a means to estimate the molecular mass of these receptors. The availability of substantial amounts of purified 2-adrenergic receptor allowed determination of segments of its amino acid se- quence. This information led to the production of polynucleotide probes and eventually to cloning of the receptor gene and determi- nation of the complete primary sequence of the receptor protein. Caron and Lefkowitz review the investigations leading to this major development and discuss the methods involved. They analyze our current perception of the relation of receptor function to its structure and discuss the general features of the G protein-interacting receptor family, of which the -adrenergic receptors are prototypes.

Автор: M.B. Sporn; Sonia B. Jakowlew
Название: Transforming Growth Factor-Beta in Cancer Therapy, Volume I
ISBN: 161737735X ISBN-13(EAN): 9781617377358
Издательство: Springer
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Цена: 36197.00 р.
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Описание: Transforming Growth Factor- ss in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ss (TGF- ss) in cancer treatment and therapy.