Описание: A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.
Описание: This book systematically integrates essentials, advances, and clinical correlations for cardiovascular drugs. The author covers both fundamentals and pharmacology of cardiovascular drugs, as well as their applications to treat cardiovascular diseases.
Автор: Francesco Clementi,Guido Fumagalli Название: General and Molecular Pharmacology: Principles of Drug Action ISBN: 1118768574 ISBN-13(EAN): 9781118768570 Издательство: Wiley Рейтинг: Цена: 20109.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with a particular attention to the mechanisms of drug action the fundamental basis for proper clinical use without neglecting toxicology and pharmacokinetics.
Автор: R.B. Barlow Название: Quantitative Aspects of Chemical Pharmacology ISBN: 0709903006 ISBN-13(EAN): 9780709903000 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Stephen M. Roberts; James P. Kehrer; Lars-Oliver K Название: Studies on Experimental Toxicology and Pharmacology ISBN: 331934708X ISBN-13(EAN): 9783319347080 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research.
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