Автор: Bernd Nilius; Thomas Gudermann; Reinhard Jahn; Rol Название: Reviews of Physiology, Biochemistry and Pharmacology 166 ISBN: 3319382330 ISBN-13(EAN): 9783319382333 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology.
Автор: K. Dose Название: The Origin of Life and Evolutionary Biochemistry ISBN: 1468421174 ISBN-13(EAN): 9781468421170 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The primary metabolism of protobionts was probably based on the electron transfer reactions regulated by catalysts or photo- sensitizing pigments. The action of photoreceptive pigments was inevitable in the case of electron transfer leading to light energy storage in the reaction products. The primitive tetrapyrrolic pig- ments formed abiogenically (porphin, chlorin) as well as their more complicated biogenic analogs (chlorophylls) are capable of photo- sensitizing electron transfer in systems, having various degrees of molecular complexity. The inorganic photosensitizers (titanium dioxide. zinc oxide. etc.). being excited in the near ultraviolet. are able to perform the same reactions as porphyrins--electron transfer from donor to acceptor molecule (including photoreduction of viologens) or water molecule photooxidation (oxygen liberation). coupled with reduction of ferric compounds and quinones. The in- organic photosensitizers are not used in biological evolution; actually the inorganic ions entered into tetrapyrrolic cycle. form- ing effective photocatalysts. Inclusion of pigments into primary membranes led to elaborated coupling between pigments and enzymatic systems. The involvement of the excited pigments into the biocata- lytic electron transfer chain was prerequisite to effective func- tion of photosynthetic organisms. REFERENCES 1. Oparin. A. I., "Origin of Life on Earth," Izd. AN SSSR. Moscow. 1957. 2. Gaffron, H., in: "Horizons in Biochemistry" (Kasha. M -- and Pullmann, B -- eds.), p. 59. Academic Press, New York. 1962. 3. Calvin. M -- "Chemical Evolution," C1arendon Press, Oxford. 1969. 4. Pasynsky. A. G .- and Pav1ovskaya. T. E .- Uspekhii khimii 33, 1198 (1964).
Автор: G. N. Cohen Название: Microbial Biochemistry ISBN: 9401776261 ISBN-13(EAN): 9789401776264 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Microbial physiology, biochemistry and genetics allowed the formulation of concepts that turned out to be important in the study of higher organisms. In the first section, the principles of bacterial growth are given, as well as the description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from the outside media through different permeability mechanism described in detail. A chapter is devoted to allostery and is indispensable for the comprehension of many regulatory mechanisms described throughout the book. Another section analyses the mechanisms by which cells obtain the energy necessary for their growth, glycolysis, the pentose phosphate pathway, the tricarboxylic and the anaplerotic cycles. Two chapters are devoted to classes of microorganisms rarely dealt with in textbooks, namely the Archaea, mainly the methanogenic bacteria, and the methylotrophs. Eight chapters describe the principles of the regulations at the transcriptional level, with the necessary knowledge of the machineries of transcription and translation. The next fifteen chapters deal with the biosynthesis of the cell building blocks, amino acids, purine and pyrimidine nucleotides and deoxynucleotides, water-soluble vitamins and coenzymes, isoprene and tetrapyrrole derivatives and vitamin B12. The two last chapters are devoted to the study of protein-DNA interactions and to the evolution of biosynthetic pathways. The considerable advances made in the last thirty years in the field by the introduction of gene cloning and sequencing and by the exponential development of physical methods such as X-ray crystallography or nuclear magnetic resonance have helped presenting metabolism under a multidisciplinary attractive angle.
Автор: Bernd Nilius; Thomas Gudermann; Reinhard Jahn; Rol Название: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167 ISBN: 3319364073 ISBN-13(EAN): 9783319364070 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology.
Автор: Swaminathan Название: HB of Clinical Biochemistry.2003 ISBN: 0195652525 ISBN-13(EAN): 9780195652529 Издательство: Oxford Academ Цена: 4117.00 р. Наличие на складе: Поставка под заказ.
Описание: "Handbook of Clinical Biochemistry" provides an understanding of the pathophysiological basis of diseases and gives guidelines about the use of clinical biochemistry laboratories. It aims to bring together physiology, biochemistry and relevant pathology for the proper use of the laboratory and enable interpretation of results.
Автор: L. Jaenicke Название: Biochemistry of Sensory Functions ISBN: 3642660142 ISBN-13(EAN): 9783642660146 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Hans H. Weber Название: Molecular Bioenergetics and Macromolecular Biochemistry ISBN: 3642653111 ISBN-13(EAN): 9783642653117 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Meyerhof Symposium on "Molecular Bioenergetics and Macromolecular Biochemistry" took place in Heidelberg from the 5th to the 8th of July, 1970.
Автор: Jan Barciszewski; Brian F.C. Clark Название: RNA Biochemistry and Biotechnology ISBN: 0792358619 ISBN-13(EAN): 9780792358619 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop, Poznan, Poland, 10-17 October, 1998
Автор: Philip K. Moore; Matt Whiteman Название: Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide ISBN: 3319359096 ISBN-13(EAN): 9783319359090 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.
Автор: David B. Lombard Название: Biochemistry and Genetics of Recq-Helicases ISBN: 0792379845 ISBN-13(EAN): 9780792379843 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The RecQ-family helicases are a group of helicases which have important roles in the maintenance of genomic stability in many organisms. In humans, mutations in three RecQ-family helicases lead to disease. This book examines these helicases. It is intended for the researchers invested in these particular disorders.
Автор: R. H. Adrian; E. Helmreich; H. Holzer; R. Jung; K. Название: Reviews of Physiology, Biochemistry and Experimental Pharmacology ISBN: 3540062386 ISBN-13(EAN): 9783540062387 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: L. V. Pevzner Название: Functional Biochemistry of the Neuroglia ISBN: 1468416375 ISBN-13(EAN): 9781468416374 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The first issue of the Sechenov Journal of Physiology began with an arti'cle by George E. Vladimirov entitled "Functional Bio- chemistry of the Brain - some conclusions and perspectives". Vladimirov wrote (p. 4): While there has been great success in the study of physiological aspects of higher nervous activity, we tend to ignore the physico-chemical nature of such fundamental physiological phenomena as the processes of excitation and inhibition in the nervous system. Elucidation of the chemical bases of these phenomena, and understanding of the spatio-temporal details of their functioning must be the aim of functional biochemistry of the brain, a subject of growing interest in our" country. And later, considering the difficulties of investigation of the brain by conventional biochemical methods, Vladimirov remarked, "In different samples of the brain taken for analysis, variation may occur in such factors as the structure of the cellular layers of the grey matter, the ratio between neuronal glial elements, (emphasis mine, L.P.) and the proportion of intercellular material.
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