Modern Trends in Human Leukemia IV, R. Neth; R. C. Gallo; T. Graf; K. Mannweiler; K. W

Автор: Shaoguang Li; Haojian Zhang
Название: Chronic Myeloid Leukemia
ISBN: 1493940090 ISBN-13(EAN): 9781493940097
Издательство: Springer
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Цена: 18167.00 р.
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Описание:

1. Molecular Detection of BCR-ABL in Chronic Myeloid Leukemia

Автор: Anjali S. Advani; Hillard M. Lazarus
Название: Adult Acute Lymphocytic Leukemia
ISBN: 149395766X ISBN-13(EAN): 9781493957668
Издательство: Springer
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Цена: 30745.00 р.
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Описание: The current explosion of new areas of controversy in the treatment of acute lymphocytic leukemia in adults and young adults makes this comprehensive book a much needed reference for hematologists and oncologists. This book assembles leading authorities from around the globe to cover the full spectrum of ALL subtypes and their treatments. Specific topics of discussion include indications for allogeneic bone marrow transplant in first complete remission, the role of minimal residual disease in making treatment decisions, the treatment of young adults, and the treatment of Philadelphia chromosome positive ALL with the advent of the tyrosine kinase inhibitors. This is the first book to focus exclusively on the adult ALL patient. It provides a complete overview of diagnosis, molecular pathogenesis, evaluation, and treatment for this important patient population.

Автор: R. Neth; R. C. Gallo; M. F. Greaves; M. A. S. Moor
Название: Modern Trends in Human Leukemia V
ISBN: 3540118586 ISBN-13(EAN): 9783540118589
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Organized on behalf of the Deutsche Gesellschaft fur Hamatologie und Onkologie, Wilsede, June 21-23, 1982

Автор: Rolf Neth; Robert C. Gallo; Melvyn F. Greaves; Gri
Название: Modern Trends in Human Leukemia VI
ISBN: 3540153292 ISBN-13(EAN): 9783540153290
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Organized on behalf of the Deutsche Gesellschaft fur Hamatologie und Onkologie. Wilsede, June 17-20, 1984 Wilsede Joint Meeting on Pediatric Oncology III. Hamburg, June 21/22, 1984.

Автор: Rolf Neth; Robert C. Gallo; Melvyn F. Greaves; Ger
Название: Modern Trends in Human Leukemia VIII
ISBN: 3540509674 ISBN-13(EAN): 9783540509677
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Organized on behalf of the Deutsche Gesellschaft fur Hamatologie und Onkologie, Hamburg, June 18, 1988 and Wilsede, June 19-23, 1988. Wilsede Joint Meeting on Pediatric Oncology V, Hamburg, June 17, 1988

Автор: Rolf Neth; Elena Frolova; Robert C. Gallo; Melvyn
Название: Modern Trends in Human Leukemia IX
ISBN: 3540543600 ISBN-13(EAN): 9783540543602
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Organized on behalf of the Deutsche Gesellschaft fur Hamatologie und Onkologie,Wilsede, June 17-21, 1990

Автор: P.K. Vogt
Название: Human T-Cell Leukemia Virus
ISBN: 3642701159 ISBN-13(EAN): 9783642701153
Издательство: Springer
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Цена: 18167.00 р.
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Описание: characteristic features in common with the genome of other retroviruses: long terminal repeats (L TR), and coding regions for internal proteins (gag), for re- verse transcriptase (pol), and for glycosylated virion surface proteins (env) , ar- ranged in the sequence gag, pol, env from the 5` to the 3` end of the genome.

Автор: G.J.L. Kaspers; R. Pieters; A.J.P. Veerman
Название: Drug Resistance in Leukemia and Lymphoma III
ISBN: 0306460556 ISBN-13(EAN): 9780306460555
Издательство: Springer
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Цена: 38992.00 р.
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Описание: This volume covers all important aspects of drug resistance in leukemia and lymphoma. General mechanisms of resistance are discussed, including the drug resistance related proteins, MRP (multi drug resistance protein) and LRP (lung resistance protein), and the role of glutathione.

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: Sami Malek
Название: Advances in Chronic Lymphocytic Leukemia
ISBN: 1493953893 ISBN-13(EAN): 9781493953899
Издательство: Springer
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Цена: 20896.00 р.
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Описание: In this book, the authors focus on crucial aspects of chronic lymphocytic leukemia (CLL) pathogenesis and delineate the known and unknown in CLL to inform readers and to motivate out of the box thinking in future CLL research.

Автор: Masahiro Kizaki
Название: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia
ISBN: 4431562559 ISBN-13(EAN): 9784431562559
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development.

Автор: Reaman
Название: Childhood leukemia
ISBN: 3642137806 ISBN-13(EAN): 9783642137808
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book is a comprehensive and up-to-date compendium on all aspects of childhood leukemia. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.