Chronic Myeloid Leukemia, Shaoguang Li; Haojian Zhang

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493913921 ISBN-13(EAN): 9781493913923
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: W. Hiddemann; R. Mertelsmann
Название: New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia
ISBN: 3540526137 ISBN-13(EAN): 9783540526131
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Provides information about the current status of aclacinomycin A for the treatment of haematologic malignancies. The text includes accounts of the action of aclacinomycin A in myelodysplastic syndromes and of its efficacy in acute myeloid leukemias.

Автор: Chung-Che (Jeff) Chang; Robert S. Ohgami
Название: Precision Molecular Pathology of Myeloid Neoplasms
ISBN: 3319621440 ISBN-13(EAN): 9783319621449
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.

Автор: Masahiro Kizaki
Название: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia
ISBN: 4431562559 ISBN-13(EAN): 9784431562559
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development.

Автор: Paolo Fortina; Eric Londin; Jason Y. Park; Larry J
Название: Acute Myeloid Leukemia
ISBN: 1493971409 ISBN-13(EAN): 9781493971404
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: Carella
Название: Chronic Myeloid Leukaemia
ISBN: 185317890X ISBN-13(EAN): 9781853178900
Издательство: Informa
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Цена: 15886.00 р.
Наличие на складе: Нет в наличии.

Описание: Drawing on the expertise of an international team of experts in chronic myeloid leukemia, this book provides insight into the latest advances and the implications those developments have for management of the disease. The editors and their panel of contributors explore many topics, including a review of molecular and cellular biology, a discussion of conventional chemotherapy and interferon therapy, and recent developments in allografting and autografting. The reader gains not only an incisive view of the biological structure of the disease, but applications of that biology to treatment modalities. The book emphasizes treatment strategies and is a guide to complex treatment options.

Автор: Richard Greil; Lisa Pleyer; Daniel Neureiter; Vikt
Название: Chronic Myeloid Neoplasias and Clonal Overlap Syndromes
ISBN: 3709120039 ISBN-13(EAN): 9783709120033
Издательство: Springer
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Цена: 30745.00 р.
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Описание: Introduction The understanding of the genetic, epigenetic, immuno- well as for practicing hematologists or oncologists. logical and biological causes of myeloproliferative dis- Each chapter follows a similar architecture and leads orders has substantially improved in the last few years. through epidemiology, genetic and molecular causes, Together with refined tools in pathology, the successful hematological and clinical findings, prognostic factors establishment of mouse models mimicking at least some and current treatment approaches of the diseases. of the myeloproliferative disorders, and murine models Effort has been made to point out the evolving field of novel drugs in this arena but simultaneously diff- allowing to carefully dissect the role of mutations and gene dosage effects of, for example JAK2, this has led to entiate between standard and experimental treatment ever increasing numbers of modified classification approaches. schemes. It is therefore important for the heamtologist Together with the co-editors and all the authors of or oncologist to keep up with this rapid change in classi- the various chapters I hope that the readers of the book fication language, the upcoming of new entities or differ- will enjoy reading and benefit from the information entiation between, or subclassification of, rare diseases provided.

Автор: Escors, David Talmadge, James E. Breckpot, Karine Van Ginderachter, Jo A. Kochan, Grazyna
Название: Myeloid-derived suppressor cells and cancer
ISBN: 3319268198 ISBN-13(EAN): 9783319268194
Издательство: Springer
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Цена: 9141.00 р.
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Описание: The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting.

Автор: Grace L.C. Shen-Ong; Michael Potter; Neal G. Copel
Название: Mechanisms in Myeloid Tumorigenesis 1988
ISBN: 364274625X ISBN-13(EAN): 9783642746253
Издательство: Springer
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Цена: 18167.00 р.
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Автор: Sami Malek
Название: Advances in Chronic Lymphocytic Leukemia
ISBN: 1493953893 ISBN-13(EAN): 9781493953899
Издательство: Springer
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Цена: 20896.00 р.
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Описание: In this book, the authors focus on crucial aspects of chronic lymphocytic leukemia (CLL) pathogenesis and delineate the known and unknown in CLL to inform readers and to motivate out of the box thinking in future CLL research.

Автор: Federico Caligaris-Cappio; Riccardo Dalla Favera
Название: Chronic Lymphocytic Leukemia
ISBN: 3642064507 ISBN-13(EAN): 9783642064500
Издательство: Springer
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Цена: 32004.00 р.
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Описание: For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL.