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Chronic Myeloid Neoplasias and Clonal Overlap Syndromes, Richard Greil; Lisa Pleyer; Daniel Neureiter; Vikt


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Автор: Richard Greil; Lisa Pleyer; Daniel Neureiter; Vikt
Название:  Chronic Myeloid Neoplasias and Clonal Overlap Syndromes
ISBN: 9783709120033
Издательство: Springer
Классификация:

ISBN-10: 3709120039
Обложка/Формат: Paperback
Страницы: 295
Вес: 0.76 кг.
Дата издания: 23.08.2016
Язык: English
Издание: Softcover reprint of
Иллюстрации: Xi, 295 p.; xi, 295 p.
Размер: 279 x 210 x 17
Читательская аудитория: General (us: trade)
Основная тема: Medicine & Public Health
Подзаголовок: Epidemiology, Pathophysiology and Treatment Options
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Introduction The understanding of the genetic, epigenetic, immuno- well as for practicing hematologists or oncologists. logical and biological causes of myeloproliferative dis- Each chapter follows a similar architecture and leads orders has substantially improved in the last few years. through epidemiology, genetic and molecular causes, Together with refined tools in pathology, the successful hematological and clinical findings, prognostic factors establishment of mouse models mimicking at least some and current treatment approaches of the diseases. of the myeloproliferative disorders, and murine models Effort has been made to point out the evolving field of novel drugs in this arena but simultaneously diff- allowing to carefully dissect the role of mutations and gene dosage effects of, for example JAK2, this has led to entiate between standard and experimental treatment ever increasing numbers of modified classification approaches. schemes. It is therefore important for the heamtologist Together with the co-editors and all the authors of or oncologist to keep up with this rapid change in classi- the various chapters I hope that the readers of the book fication language, the upcoming of new entities or differ- will enjoy reading and benefit from the information entiation between, or subclassification of, rare diseases provided.
Дополнительное описание: to “Classic” Chronic Myeloproliferative Disorders (CMPDs) — Molecular and Cellular Biology.- Essential Thrombocythemia (ET).- Polycythemia Vera (PV).- Primary Myelofibrosis (PMF) [Previously Chronic Idiopathic Myelofibrosid (CIMF), Myelofibrosis with Myel



The Myelodysplastic Syndromes

Автор: V?rkonyi
Название: The Myelodysplastic Syndromes
ISBN: 9400704399 ISBN-13(EAN): 9789400704398
Издательство: Springer
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Цена: 28734.00 р.
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Описание: Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias.MDS was previously named as  “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia.According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged  70  or older. It is believed that the true incidence of MDS have been underestimated however it seems to be comparable to that for multiple myeloma and chronic lymphocytic leukemia.  In the past decade much progress had been made; we know more on the disease pathology, there is more emphasis on the care and more targeted therapy had been invested. Athors provide updated knowledge in this book on all clinically important aspects of the disease. Hot topics of our days are discussed in chapters by outstanding and well known scientists from all over the world. We would offer this product both for medical students and postgraduates as well as for all who are interested in this very exciting and fast progressing field of hematology.With this work authors should call attention on the disease for decision makers in healt care systems as well. 

Precision Molecular Pathology of Myeloid Neoplasms

Автор: Chung-Che (Jeff) Chang; Robert S. Ohgami
Название: Precision Molecular Pathology of Myeloid Neoplasms
ISBN: 3319621440 ISBN-13(EAN): 9783319621449
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.

Targeted Therapy of Acute Myeloid Leukemia

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Lymphoid Neoplasias I

Автор: G. Mathe; M. Seligmann; M. Tubiana
Название: Lymphoid Neoplasias I
ISBN: 3642812481 ISBN-13(EAN): 9783642812484
Издательство: Springer
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Цена: 18167.00 р.
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Описание: CNRS International Colloquium, Held in Paris on June 22-24, 1977

Lymphoid Neoplasias II

Автор: G. Mathe; M. Seligmann; M. Tubiana
Название: Lymphoid Neoplasias II
ISBN: 3642812511 ISBN-13(EAN): 9783642812514
Издательство: Springer
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Цена: 18167.00 р.
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Описание: CNRS International Colloquium, Held in Paris on June 22-24, 1977

AIDS-Related Neoplasias

Автор: Luzius Schmid; Hans-J?rg Senn
Название: AIDS-Related Neoplasias
ISBN: 3642834728 ISBN-13(EAN): 9783642834721
Издательство: Springer
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Цена: 6986.00 р.
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Chronic Myeloid Leukaemia

Автор: Carella
Название: Chronic Myeloid Leukaemia
ISBN: 185317890X ISBN-13(EAN): 9781853178900
Издательство: Informa
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Цена: 15886.00 р.
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Описание: Drawing on the expertise of an international team of experts in chronic myeloid leukemia, this book provides insight into the latest advances and the implications those developments have for management of the disease. The editors and their panel of contributors explore many topics, including a review of molecular and cellular biology, a discussion of conventional chemotherapy and interferon therapy, and recent developments in allografting and autografting. The reader gains not only an incisive view of the biological structure of the disease, but applications of that biology to treatment modalities. The book emphasizes treatment strategies and is a guide to complex treatment options.

Chronic Myeloid Leukemia

Автор: Shaoguang Li; Haojian Zhang
Название: Chronic Myeloid Leukemia
ISBN: 1493940090 ISBN-13(EAN): 9781493940097
Издательство: Springer
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Цена: 18167.00 р.
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Описание:

1. Molecular Detection of BCR-ABL in Chronic Myeloid Leukemia

Ya-Zhen Qin and Xiao-Jun Huang

2. Induction of Chronic Myeloid Leukemia in Mice

Haojian Zhang and Shaoguang Li

3. CML Mouse Model Generated from Leukemia Stem Cells

Yiguo Hu

4. Immunological Analyses of Leukemia Stem Cells

Kazuhito Naka and Yoshihiro Takihara

5. Cell Cycle Analysis of CML Stem Cells using Hoechst33342 and Propidium Iodide

Ngoc DeSouza, Megan Zhou, and Yi Shan

6. Histological and In Vivo Microscopic Analysis of the Bone Marrow Microenvironment in a Murine Model of Chronic Myelogenous Leukemia

Eva S. Weissenberger and Daniela S. Krause

7. The Culture Repopulation Ability (CRA) Assay and Incubation in Low Oxygen to Test Anti-Leukemic Drugs on Imatinib-resistant CML Stem-like Cells

Giulia Cheloni and Michele Tanturli

8. Tumor Suppressor Analysis in CML

Oliver Herrmann and Mirle Schemionek

9. Detecting Autophagy and Autophagy Flux in Chronic Myeloid Leukemia Cells Using a Cyto ID Fluorescence Spectrophotometric Assay

Sujuan Guo, Kevin Pridham, and Zhi Sheng

10. DREAM, A Simple Method for DNA Methylation Profiling by High Throughput Sequencing

Jaroslav Jelinek and Jozef Madzo

11. ChIP-seq Analysis of Human Chronic Myeloid Leukemia Cells

Lars Anders and Zhaodong Li

12. Quantitative Proteomics Analysis of Leukemia Cells

Sebastian Halbach, Jцrn Dengjel, and Tilman Brummer

13. A Convenient Cell Culture Model for CML Acquired Resistance through BCR-ABL Mutations

Zhiqiang Wang and WenYong Chen

14. High Throughput Screening of Tyrosine Kinase Inhibitor Resistant Genes in CML

Leyuan Ma, Justine Roderick, Michelle A. Kelliher, and Michael R. Green

15. Biological Analysis of Human CML Stem Cells; Xenograft Model of Chronic Phase Human Chronic Myeloid Leukemia

Sheela A. Abraham

16. New Mouse Models to Investigate the Efficacy of Drug Combinations in Human Chronic Myeloid Leukemia

Hanyang Lin, Adrian Woolfson, and Xiaoyan Jiang

17. miRNome Analysis of CML Cells

Yadong Yang, Nan Ding, Xunong Dong, Xiangdong Fang

18. An Integrative Analysis of microRNA and mRNA Profiling in CML Stem Cells

Farah Nassar, Rabab El Eit, and Rihab Nasr

19. Single Cell Cytokine Profiling to Investigate Cellular Functional Diversity in Hematopoietic Malignancies

Jonathan J. Chen, Minsuk Kwak, and Rong Fan

Myeloid-derived suppressor cells and cancer

Автор: Escors, David Talmadge, James E. Breckpot, Karine Van Ginderachter, Jo A. Kochan, Grazyna
Название: Myeloid-derived suppressor cells and cancer
ISBN: 3319268198 ISBN-13(EAN): 9783319268194
Издательство: Springer
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Цена: 9141.00 р.
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Описание: The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting.

Acute Myeloid Leukemia

Автор: Paolo Fortina; Eric Londin; Jason Y. Park; Larry J
Название: Acute Myeloid Leukemia
ISBN: 1493971409 ISBN-13(EAN): 9781493971404
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.

New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia

Автор: W. Hiddemann; R. Mertelsmann
Название: New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia
ISBN: 3540526137 ISBN-13(EAN): 9783540526131
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Provides information about the current status of aclacinomycin A for the treatment of haematologic malignancies. The text includes accounts of the action of aclacinomycin A in myelodysplastic syndromes and of its efficacy in acute myeloid leukemias.

Mechanisms in Myeloid Tumorigenesis 1988

Автор: Grace L.C. Shen-Ong; Michael Potter; Neal G. Copel
Название: Mechanisms in Myeloid Tumorigenesis 1988
ISBN: 364274625X ISBN-13(EAN): 9783642746253
Издательство: Springer
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Цена: 18167.00 р.
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